Bacteriostatic toothpaste containing bamboo shavings triterpenes, and preparation method thereof

A bamboo toothpaste technology, applied in dentistry, pharmaceutical formulations, local antibacterial agents, etc., can solve problems such as flora imbalance, ulcers, and oral micro-ecological damage, achieve fresh breath, improve oral health, and solve solubility problems. Effect

Inactive Publication Date: 2020-07-10
上海绿瑞生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although the existing broad-spectrum antibiotics and chemical synthetic drugs can effectively kill oral pathogenic bacter

Method used

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  • Bacteriostatic toothpaste containing bamboo shavings triterpenes, and preparation method thereof
  • Bacteriostatic toothpaste containing bamboo shavings triterpenes, and preparation method thereof
  • Bacteriostatic toothpaste containing bamboo shavings triterpenes, and preparation method thereof

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Experimental program
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preparation example Construction

[0101] In a preferred embodiment, the antibacterial toothpaste containing bamboo triterpenes is aqueous toothpaste, and the preparation method of the aqueous toothpaste comprises the following steps:

[0102] (1) Add the thickener into the humectant, stir and mix evenly to obtain mixture 1, and set aside;

[0103] (2) Add bamboo triterpene into the solubilizer, heat to 50-80°C, start stirring, mix and dissolve to obtain mixture 2, and set aside;

[0104] (3) Add the mixture 1 into the humectant under stirring condition, stir and mix evenly to obtain the mixture 3;

[0105] (4) Add mixture 2 to mixture 3 under stirring conditions, stir and mix evenly to obtain mixture 4;

[0106] (5) Add sweetener, pyrophosphate, anti-caries agent and preservative to mixture 4 under stirring condition, stir and mix evenly to obtain mixture 5;

[0107] (6) Add friction agent into mixture 5 under stirring condition, stir and mix evenly to obtain mixture 6;

[0108] (7) Under the condition of s...

Embodiment 1

[0134] Embodiment 1 of the present invention provides a kind of bacteriostasis toothpaste containing triterpenoid, comprising the following ingredients in parts by weight: 0.1 part of triterpenoid, 1 part of solubilizer, 20 parts of friction agent, 12.86 parts of pyrophosphate 1 part of thickener, 0.24 part of anti-caries agent, 3 parts of foaming agent, 60 parts of moisturizing agent, 0.3 part of sweetener, 0.5 part of preservative, and 1 part of essence.

[0135] The solubilizer is polyglyceryl-10 laurate.

[0136] The friction agent is hydrated silica.

[0137] The hydrated silica is spherical silica with a particle size of 20 μm.

[0138] The pyrophosphate is tetrasodium pyrophosphate.

[0139] The thickener is xanthan gum and sodium cellulose.

[0140] The thickener contains 0.5 parts by weight of xanthan gum and 0.5 parts by weight of sodium cellulose.

[0141] The anti-caries agent is sodium fluoride.

[0142] The foaming agent is sodium lauryl sulfate and cocamido...

Embodiment 2

[0157] Embodiment 2 of the present invention provides a kind of antibacterial toothpaste containing triterpenoids, comprising the following ingredients in parts by weight: 0.01 part of triterpenoids, 1 part of solubilizer, 20 parts of friction agent, 12.86 parts of pyrophosphate 1 part of thickener, 0.24 part of anti-caries agent, 3 parts of foaming agent, 60 parts of moisturizing agent, 0.3 part of sweetener, 0.5 part of preservative, and 1 part of essence.

[0158] The solubilizer is polyglyceryl-10 laurate.

[0159] The friction agent is hydrated silica.

[0160] The hydrated silica is spherical silica with a particle size of 20 μm.

[0161] The pyrophosphate is tetrasodium pyrophosphate.

[0162] The thickener is xanthan gum and carbomer.

[0163] The thickener contains 0.1 parts by weight of xanthan gum and 0.9 parts by weight of carbomer.

[0164] The anti-caries agent is sodium fluoride.

[0165] The foaming agent is sodium methyl cocoyl taurate and cocamidopropyl ...

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Abstract

The invention relates to the technical field of daily chemicals, and more specifically, the invention relates to a bacteriostatic toothpaste containing bamboo shavings triterpenes, and a preparation method thereof. A natural, healthy, green and safe botanical drug ''bamboo shavings triterpenes'' is used as a raw material, and a friction agent, a phosphate, a solubilizer and the like in the systemare synergized to prepare the natural bacteriostatic toothpaste. The prepared bacteriostatic toothpaste can effectively inhibit the growth of common oral pathogenic bacteria such as Porphyromonas gingivalis, Streptococcus mutans, Candida albicans, Helicobacter pylori, Staphylococcus aureus, and Escherichia coli, can remove some odor-causing bacteria and oral residual odor-causing substrates, and inhibits the increase of cariogenic bacteria, periodontal pathogens, and oral lichen planus pathogens. In the bacteriostatic toothpaste containing bamboo shavings triterpenes of the invention, the friction agent hydrated silica with a special type and tetrasodium pyrophosphate are added, and thereby a biofilm on the tooth surface is removed by mechanical friction and dissociation. The synergy of hydrated silica and tetrasodium pyrophosphate solves the barrier of the prior art.

Description

technical field [0001] The invention relates to the technical field of daily chemical products, and more specifically, the invention relates to a bacteriostatic toothpaste containing bamboo triterpenes and a preparation method thereof. Background technique [0002] The oral health status of the Chinese population is not optimistic, the caries rate is increasing year by year, and oral problems such as bleeding gums and periodontitis are common. The oral cavity is one of the main entrances for the human body to directly contact with the external environment. Its internal environment is warm and humid, which is suitable for the survival and proliferation of various bacterial flora. Therefore, various external intrusions and internal bacterial flora are densely distributed in the oral cavity. Oral diseases such as periarthritis and halitosis are mainly caused by pathogenic bacteria. Streptococcus mutans and Streptococcus sobrinus are the main cariogenic bacteria, which decompose...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/25A61K8/24A61K8/21A61P1/02A61P31/02A61Q11/00
CPCA61K8/21A61K8/24A61K8/25A61K8/9794A61P1/02A61P31/02A61Q11/00
Inventor 姜春鹏张英张明磊
Owner 上海绿瑞生物科技有限公司
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