Microporous composite biological ceramic bone repair scaffold as well as preparation method and device thereof

Abstract

The invention discloses a microporous composite biological ceramic bone repair scaffold and a preparation method and device thereof. The repair scaffold comprises a repair scaffold body made of a composite material, the repair scaffold body comprises a plurality of scaffold layers which are overlapped, a plurality of micron-sized micropores are formed in each scaffold layer, and a plurality of micropores among the layers form a plurality of polyhedrons. The composite material comprises the following components in percentage by weight: 1%-5% of graphene, 50%-60% of zirconium oxide and 20%-40% of hydroxyapatite and beta-tricalcium phosphate. The polyhedrons are connected by the micropores, the conductivity and the high toughness of the graphene are utilized, the high strength and the wear resistance of the zirconium oxide are utilized, and the good bone induction activity of the hydroxyapatite and beta-tricalcium phosphate is utilized, so that the physical properties such as compressivestrength, elastic modulus, fracture toughness and other indexes of the new material are close to natural bone tissue, the new material can bear the large stress deformation without fracture, the wearcondition between the material and the adjacent tissue is reduced, and the new material has high osteogenesis induction activity at the same time.

Description

technical field [0001] The invention relates to the field of oral and maxillofacial bone defect repair, in particular to a microporous composite bioceramic bone repair bracket and a preparation method and device thereof. Background technique [0002] The current bone defect repair techniques are as follows: [0003] Repair methods for jaw defects: such as Figure 8 As shown, diseases such as oral and maxillofacial trauma, tumors, congenital deformities, and infections often lead to partial or even overall defects of maxillofacial bone tissue. At present, there are a series of difficult problems in the treatment of patients with bone tissue defects in the oral and maxillofacial region, especially those with large-scale bone defects. Accompanied by facial tissue displacement, deformity, poor bone union, nonunion, bone exposure and other problems. In current clinical practice, such as Figure 9 In (a) and (b), Figure 10 As shown, large maxillofacial bone tissue defects are...

AI Technical Summary

Problems solved by technology

[0007] It can be seen from Table 1 that the current single-component ceramic materials are quite different from human natural bone in terms of biomechanical properties, such as the index elastic modulus, fracture toughness, compressive strength and tensile strength in the table.

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