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Application of an aqueous extract of pine nut shells in blood lipid-lowering drugs

A blood lipid-lowering drug and pine nut shell technology, applied in the field of medicine, can solve problems such as waste of resources, achieve the effects of increasing the content of cholesterol, reducing the content of total cholesterol, and enhancing the body's immunity

Active Publication Date: 2022-02-08
INNER MONGOLIA UNIVERSITY
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  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

Due to insufficient attention, these wastes are only used as firewood except for a very small amount of dyes and activated carbon, resulting in a great waste of resources

Method used

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  • Application of an aqueous extract of pine nut shells in blood lipid-lowering drugs
  • Application of an aqueous extract of pine nut shells in blood lipid-lowering drugs
  • Application of an aqueous extract of pine nut shells in blood lipid-lowering drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0021] 1. Blood lipid-lowering efficacy experiment of Korean pine pine nut shell water extract

[0022] (1) Experimental materials

[0023] Experimental drugs and reagents:

[0024] The pine nut shells of Korean pine were purchased in Changchun, Jilin.

[0025] Simvastatin, produced by Guangdong Bidi Pharmaceutical Co., Ltd.; approval number: Guoyao Zhunzi 20066221

[0026] Total cholesterol kit, produced by Zhongsheng Beikong Biotechnology Co., Ltd.; product batch number: 141741, product registration number: Beijing Drug Administration (Zhun) No. 2011 No. 2400202

[0027] Triglyceride kit, produced by Zhongsheng Beikong Biotechnology Co., Ltd.; production batch number: 136331, product registration number: Beijing Drug Administration (Quasi) Word 2011 No. 2400202

[0028] High-density lipoprotein cholesterol kit, produced by Zhongsheng Beikong Biotechnology Co., Ltd.; production batch number: 140551, product registration number: Beijing Drug Administration (Quasi) Word 2011...

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Abstract

The invention provides an application of an aqueous extract of Korean pine pine nut shells in the preparation of blood lipid-lowering medicines or blood fat-lowering health care products, and belongs to the technical field of medicine. Crushing the pine nut shells of Korean pine, adding water to reflux, and concentrating the filtrate can obtain the water extract of the pine nut shells. The aqueous extract of pine nut shells administered to high-fat model rats by intragastric administration can significantly reduce serum total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) in high-fat model rats, and It can significantly increase the serum high-density lipoprotein cholesterol (HDL-C) of high-fat model rats. The above-mentioned Korean pine pine nut shell aqueous extract has the effect of regulating blood lipids, and the pine nut shell is the waste of Korean pine pine nuts, and the raw material is easy to obtain, cheap and simple, and can be used in the preparation of drugs for preventing and treating hyperlipidemia and lipid-lowering health food .

Description

technical field [0001] The application relates to the technical field of medicine, in particular, to the application of the aqueous extract of pine nut shells of Korean pine in the preparation of blood lipid-lowering drugs. Background technique [0002] Blood lipid is the general term for neutral fat and lipid substances in plasma. The main components are triglyceride (triglyceride, TG), total cholesterol (total cholesterol, TC), low-density lipoprotein cholesterol (low-density lipoprotein cholesterol, LDL-C) And high-density lipoprotein cholesterol (high-density lipoprotein cholesterol, HDL-C) and so on. When the level of one or several lipids in the blood increases (HDL-C decreases), and the content exceeds the normal value, it is called hyperlipidemia (hyperlipidemia), referred to as hyperlipidemia. Dyslipidemia generally has no abnormal manifestations in the body, but persistent hyperlipidemia, lipids in the blood are deposited on the arterial wall to form atherosclerot...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/15A23L33/105A61P3/06A61P1/16A61K131/00
CPCA61K36/15A61P3/06A61P1/16A23L33/105A61K2236/331A61K2236/39A61K2236/53A61K2236/51A23V2002/00A23V2200/3262A23V2200/32A23V2250/21
Inventor 领小鲍明明苏雅拉图孟和昭日格图
Owner INNER MONGOLIA UNIVERSITY
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