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Female lower genital tract mucosa protection and regeneration spray and preparation method thereof

A mucosal protection and reproductive tract technology, applied in diseases, antiviral agents, pharmaceutical formulations, etc., can solve the problems of female lower reproductive tract mucosal protection and mucosal regeneration repair, and achieve the goal of preventing diseased microorganisms Effect

Pending Publication Date: 2020-10-09
HEILONGJIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem that the existing gynecological care products only focus on covering the peculiar smell and treating the surface symptoms of itching, but fail to protect and regenerate the female lower reproductive tract mucosa, and provide a female lower reproductive tract Road mucous membrane protection, regeneration spray and preparation method thereof

Method used

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  • Female lower genital tract mucosa protection and regeneration spray and preparation method thereof
  • Female lower genital tract mucosa protection and regeneration spray and preparation method thereof
  • Female lower genital tract mucosa protection and regeneration spray and preparation method thereof

Examples

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specific Embodiment approach 1

[0028] Embodiment 1: This embodiment is a female lower reproductive tract mucosal protection and regeneration spray consisting of lactic acid, Aloe barbadensis leaf extract, butylene glycol, glycerin, PDGF-AB, TGF-B, 1,25- Prepared from dihydroxyvitamin D3, 1640 medium, albumin, polyvinylpyrrolidone, sodium carboxymethylcellulose, carbomer, poloxamer 407 and purified water.

specific Embodiment approach 2

[0029] Specific embodiment two: the difference between this embodiment and specific embodiment one is: a kind of women's lower genital tract mucosa protection, regeneration spray consists of 0.5~1.5% lactic acid, 0.4~1.4% aloe vera leaf extract by mass fraction , 1.2~3.1% butanediol, 2~4% glycerin, 3~8×10 -4 %PDGF-AB, 1~3×10 -4 %TGF-B, 100-300IU 1,25-dihydroxyvitamin D3, 40-50% 1640 medium, 0.5-1.1% albumin, 2-3% polyvinylpyrrolidone, 0.6-1.2% sodium carboxymethylcellulose , 0.3-0.5% carbomer, 0.1-0.2% poloxamer 407 and the balance purified water. Other steps are the same as in the first embodiment.

specific Embodiment approach 3

[0030] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is that a kind of female lower reproductive tract mucosal protection and regeneration spray consists of 0.5-1% lactic acid and 0.4-1% curacao by mass fraction Aloe leaf extract, 1.2~2.1% butanediol, 2~3% glycerin, 3~5×10 -4 %PDGF-AB, 1~2×10 -4%TGF-B, 100~200IU1,25-dihydroxyvitamin D3, 40~45% 1640 medium, 0.5~0.8% albumin, 2~2.5% polyvinylpyrrolidone, 0.6~0.9% sodium carboxymethylcellulose, It is prepared by 0.3-0.4% carbomer, 0.1-0.15% poloxamer 407 and the rest purified water. Other steps are the same as those in Embodiment 1 or 2.

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Abstract

The invention discloses a female lower genital tract mucosa protection and regeneration spray and a preparation method thereof, relates to a regeneration spray and a preparation method thereof, and belongs to the field of biotechnology. The invention aims to solve the problems that the existing gynecological nursing product only pays attention to covering peculiar smell, treats pruritus surface symptoms and does not have the effects of protecting female lower genital tract mucous membranes and regenerating and repairing the mucous membranes. The product is prepared from lactic acid, aloe veraleaf extract, butanediol, glycerol, PDGF-AB, TGF-B, 1, 25-dihydroxy vitamin D3, a 1640 culture medium, albumin, polyvinylpyrrolidone, sodium carboxymethyl cellulose, carbomer, poloxamer 407 and purified water. The prepared female lower genital tract mucosa protection and regeneration spray is suitable for protecting, regenerating and repairing female lower genital tract mucosa.

Description

technical field [0001] The invention relates to a regeneration spray and a preparation method thereof, belonging to the field of biotechnology. Background technique [0002] Humans have an innate natural defense system to fight against pathogens, which is used to resist and eliminate invading pathogens, and at the same time achieve a symbiotic balance with the body's normal microbiota. The first natural defense line of the human body is the skin and mucous membrane defense line. The human respiratory tract, digestive tract, urinary tract, and reproductive tract are all covered with mucous membranes, and there are ciliary movements on the surface of the mucous membranes. For example, the nasal hairs in the nasal cavity can block part of the droplets and dust. Sexual immunity can produce immune tolerance to symbiotic bacteria and generate immune response to pathogenic bacteria, and the symbiotic bacteria on the mucosal surface can regulate the host's systemic immune system. ...

Claims

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Application Information

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IPC IPC(8): A61K38/38A61K9/12A61K47/32A61K47/38A61K47/10A61P15/00A61P15/02A61P15/08A61P31/02A61P31/04A61P31/20A61K38/18A61K36/896A61K36/886A61K31/78A61K31/4172A61K31/405A61K31/401A61K31/198A61K31/196A61K31/19A61K31/047A61K31/593
CPCA61K38/38A61K38/1858A61K38/1841A61K36/896A61K36/886A61K31/78A61K31/4172A61K31/405A61K31/401A61K31/198A61K31/196A61K31/19A61K31/047A61K31/593A61K9/12A61K9/0034A61K47/32A61K47/38A61K47/10A61P15/00A61P15/02A61P15/08A61P31/02A61P31/04A61P31/20A61K2300/00
Inventor 马关保李剑平刘悦
Owner HEILONGJIANG PHARMA
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