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Paper diaper and preparation method thereof

A technology of diapers and hyaluronic acid, applied in the field of hygiene products, can solve the problems of skin microecological disorders, harmful skin, irritation of baby skin, etc., and achieve the effects of inhibiting growth, promoting growth and moisturizing skin

Active Publication Date: 2020-12-04
SHANDONG BLOOMAGE HYINC BIOPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent application CN107899063 A "A bacteriostatic agent and its preparation method, bacteriostatic diapers and its preparation method" provides a bacteriostatic agent and its preparation method, bacteriostatic diapers and its preparation method. Embedded in the gel carrier, cross-linked and solidified to obtain antibacterial microgel with good antibacterial effect; spray the antibacterial microgel evenly on the surface of the diaper to slowly release the antibacterial agent to avoid antibacterial The agent is diluted too quickly to achieve a long-lasting antibacterial effect. In this patent, a cross-linking agent needs to be added, and there is a risk of cross-linking agent residue. The residual cross-linking agent will cause serious irritation to the baby's skin. All microorganisms will have an effect, including skin probiotics, which will lead to human skin microecological imbalance, and long-term use is harmful to the skin
On the one hand, the residues of chemical substances in this process can irritate the immature baby's skin. On the other hand, long-term use will affect the colonization and growth of the skin's own probiotics, making the skin lose the first protective barrier. Once the use is stopped, the invasion of foreign pathogens Without resistance, the skin is more prone to lesions

Method used

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  • Paper diaper and preparation method thereof
  • Paper diaper and preparation method thereof

Examples

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preparation example Construction

[0092] In the present application, the preparation method of the powder comprises:

[0093] Dissolving hyaluronic acid, ectoine, mannitol, and Sclerotinia gelatin in lactic acid bacteria fermentation filtrate to obtain a mixed solution;

[0094] The mixed solution is filtered and sterilized and then dried to obtain powder. In this application, filter sterilization is to use 0.22 μm pore size filter membrane to filter.

[0095] Specifically, one of the lactic acid bacteria fermentation filtrates in this application is: plantarum lactobacillus preserved on a slant is inoculated into a liquid MRS medium for cultivation, cultured at 37°C for 24 hours, and the activated seeds are inoculated with 5% inoculum In the fermentation medium, ferment at 37°C for 48 hours. After the residual sugar is exhausted, sterilize with a 0.22 μm filter membrane to obtain a lactic acid bacteria fermentation filtrate.

[0096] The fermentation medium is as follows: the carbon source is one or more of...

Embodiment 1

[0138] Lactic acid bacteria fermentation filtrate is:

[0139] The Lactobacillus plantarum preserved on the slant was inoculated into the liquid MRS medium for cultivation, cultured at 37°C for 24 hours, the activated seeds were inoculated into the fermentation medium with 5% inoculum, left to ferment at 37°C for 48 hours, and the residual sugar consumption After exhaustion, filter and sterilize to obtain the lactic acid bacteria fermentation filtrate.

[0140] The fermentation medium is: carbon source is glucose 25g / L; nitrogen source is yeast powder 5g / L, peptone 10g / L; inorganic salt is disodium hydrogen phosphate 1g / L, sodium dihydrogen phosphate 1g / L, sodium acetate 5g / L L; the trace element is vitamin B2 10mg / L, and the pH is natural.

[0141] The solid product of sclerotinium gelatin is produced by Bloomage Biotechnology Co., Ltd., with a molecular weight of >2 million.

[0142] The superabsorbent resin is prepared from starch grafted with sodium polyacrylate, which i...

experiment example 1

[0158] Microbial Distribution Experiment

[0159] 105 infants were recruited, aged between 12 and 24 months, divided into 21 groups, respectively 1-21 groups, 5 people in each group, 21 groups of volunteers respectively used examples 1 to 17, and comparative examples 1 to 1 every day. For the diapers of 4, use them for 0 days, 7 days, and 14 days, and stop using them for 7 days. Use a sterile cotton swab to take samples from the skin that touches the diapers, place the samples in sterile water after mixing, and apply 100 μL each on the In Staphylococcus aureus selective screening medium, Escherichia coli selective medium, and lactic acid bacteria selective medium, the total number of colonies after cultivation, and the average test results of the total number of colonies are shown in the table below. The more colonies, the more microorganisms on the skin more.

[0160] Staphylococcus aureus differential medium:

[0161] High Salt Mannitol Agar (g / L)

[0162] Peptone 10, bee...

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Abstract

The invention discloses a paper diaper and a preparation method thereof. The prepared paper diaper comprises super absorbent resin which is arranged in a paper diaper core layer, and powder is adsorbed to the surface of the super absorbent resin; and the powder comprises hyaluronic acid, ectoin, mannitol, sclerotium gum and a lactobacillus fermentation product. After the paper diaper prepared by the method is in contact with urine on skin, when the urine is diffused into the whole core layer through the capillary action to be in contact with the super absorbent resin, the powder attached to the surface of the super absorbent resin is firstly dissolved and impregnated by liquid to permeate into a coating layer on the surface of the paper diaper to be in contact with the skin, the effects ofmoistening the skin, adjusting the skin micro-ecological environment of the skin surface of an infant, inhibiting the growth of residual pathogenic bacteria in excrement of the infant and promoting the growth of probiotics on the skin surface can be achieved, and thus the paper diaper has important application value.

Description

technical field [0001] The present application relates to the technical field of sanitary products, in particular to a paper diaper and a preparation method thereof. Background technique [0002] In recent years, with the liberalization of the two-child policy, more and more families have chosen the two-child system. As a result, infant products have received more and more attention. High-quality feeding has gradually become the basic goal pursued by parents. Among them, baby diaper products show a sharp upward trend year by year. There are many types of diapers in the market, but the quality level is uneven. Due to the poor quality of diapers, there are many skin problems in infants and young children, such as "red buttocks", "eczema", " Diaper rash" and other problems occur frequently. This kind of problem is mainly due to the fact that feces will inevitably remain in the diapers during the metabolic process after wearing them, and various pathogenic bacteria in the feces...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/40A61L15/20A61L15/60A61L15/46A61L15/44A61F13/496
CPCA61L15/28A61L15/40A61L15/20A61L15/60A61L15/46A61L15/44A61F13/496A61L2300/30A61L2300/404C08L5/08C08L5/02
Inventor 陆震魏玉洁孙元军杜冉冉李杰郭学平
Owner SHANDONG BLOOMAGE HYINC BIOPHARM CORP LTD
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