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Preparation method for preparing peptide molecules by applying enzymolysis technology

A technology using enzymes and technologies, applied in the field of preparing peptide molecules by using enzymolysis technology, can solve the problems of insufficient separation of enzymolysis products, low yield of peptide molecules, large molecular weight of peptides, etc. Enhanced enzymatic hydrolysis and small molecular weight peptides

Inactive Publication Date: 2021-01-19
SHANTOU PEIZHI FOOD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] When the existing enzymatic hydrolysis technology is in use, due to inaccurate pH and temperature control, the yield of peptide molecules is low, and the separation of enzymatic hydrolysis products is not thorough enough, so the molecular weight of the peptide is relatively large, which is not easy for human body to absorb. Therefore, We propose a method for the preparation of peptide molecules using enzymatic hydrolysis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A method for preparing peptide molecules using enzymolysis technology, comprising the steps of:

[0023] S1. Select one or more of soybeans, black beans, red beans, mung beans, peas, wheat, rice, sorghum and oats to prepare vegetable protein powder;

[0024] S2. Preparation of protein solution: Dissolve protein powder in small molecule activated water, mix evenly at a ratio of 1:3, and prepare a protein solution; preheat the protein solution in a constant temperature water bath at 90°C for 10 minutes and then cool it to 40~ 50°C;

[0025] S2. Enzymatic hydrolysis of protein: adjust the cooled protein solution with 1mol / L sodium hydroxide to keep the pH value at 5.5-6.0, then add protease, vitamin B1, vitamin E and poria cocos, and put it in a water bath at 40-50°C Underwater hydrolysis for 18-24 hours, continuously add 1mol / L sodium hydroxide during the reaction process to keep the pH value of the solution constant, adjust the pH value to 7.0 after the hydrolysis is co...

Embodiment 2

[0030] A method for preparing peptide molecules using enzymolysis technology, comprising the steps of:

[0031] S1. Select one or more of soybeans, black beans, red beans, mung beans, peas, wheat, rice, sorghum and oats to prepare vegetable protein powder;

[0032] S2. Preparation of protein solution: dissolve protein powder in small molecule activated water, mix evenly at a ratio of 1:4, and prepare protein solution; preheat the protein solution in a constant temperature water bath at 90°C for 10 minutes and then cool it to 40~ 50°C;

[0033] S2. Enzymatic hydrolysis of protein: adjust the cooled protein solution with 1mol / L sodium hydroxide to keep the pH value at 6.0-6.5, then add protease, vitamin B1, vitamin E and poria cocos, and put it in a water bath at 40-50°C Underwater hydrolysis for 18-24 hours, continuously add 1mol / L sodium hydroxide during the reaction process to keep the pH value of the solution constant, adjust the pH value to 7.0 after the hydrolysis is comp...

Embodiment 3

[0038] A method for preparing peptide molecules using enzymolysis technology, comprising the steps of:

[0039] S1. Select one or more of pigs, ducks, fish, meat, eggs, cattle, and sheep to prepare animal protein powder.

[0040] S2. Preparation of protein solution: dissolve protein powder in small molecule activated water, mix evenly at a ratio of 1:5, and prepare protein solution; preheat the protein solution in a constant temperature water bath at 90°C for 15 minutes and then cool it to 40~ 50°C;

[0041] S2. Enzymatic hydrolysis of protein: adjust the cooled protein solution with 1mol / L sodium hydroxide to keep the pH value at 5.5-6.0, then add protease, vitamin B1, vitamin E and poria cocos, and put it in a water bath at 40-50°C Underwater hydrolysis for 18-24 hours, continuously add 1mol / L sodium hydroxide during the reaction process to keep the pH value of the solution constant, adjust the pH value to 7.0 after the hydrolysis is completed, and then use ultrasonic assis...

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Abstract

The invention discloses a preparation method for preparing peptide molecules by applying an enzymolysis technology. The preparation method comprises the following steps: S1, hydrolyzing protein in small molecule activated water, carrying out uniform mixing according to a ratio of 1: (3-7), and preparing the mixture into a protein solution; preheating the protein solution in a constant-temperaturewater bath pot at the temperature of 90 DEG C for 10-15 minutes, and then cooling the protein solution to 40-50 DEG C; and S2, regulating the cooled protein solution by using 1 mol / L sodium hydroxide,enabling the pH value to be 5.5-6.5, adding protease, vitamin B1, vitamin E and poria cocos, carrying out hydrolyzing for 18-24 hours in a water bath at 40-50 DEG C, continuously adding 1 mol / L sodium hydroxide in the reaction process, enabling the pH value of the solution to be kept constant, and regulating the pH value to be 7.0 after hydrolysis is ended. According to the preparation method disclosed by the invention, ultrasonic waves are utilized to assist in enzymolysis in the enzymolysis process, so that the peptide molecules can be effectively released, the utilization rate of the raw materials is improved, and the whole process is environment-friendly.

Description

technical field [0001] The present invention relates to the technical field of peptide molecule preparation, and more specifically, relates to a method for preparing peptide molecules using enzymatic hydrolysis technology. Background technique [0002] Peptides can be chemically hydrolyzed from dietary proteins, or can be obtained artificially. They are composed of two or more amino acids and are very important in the regulation of cell physiology and metabolic functions. Active peptides are closely related to nutrition, hormones, enzyme inhibition, immune regulation, antibacterial, antiviral, and antioxidative. Peptide molecules are easily absorbed by the human body, and are suitable for people with poor protein digestion and absorption, such as middle-aged and elderly people, patients in the recovery period after surgery, patients with tumors, radiotherapy and chemotherapy, and those with poor gastrointestinal function. In addition, peptides also have the effects of impro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P21/06C07K1/36C07K1/34C07K1/16C07K1/14
CPCC07K1/14C07K1/16C07K1/34C07K1/36C12P21/06
Inventor 吴胜武
Owner SHANTOU PEIZHI FOOD