A preparation method for 3D printing femoral head with customizable regenerative porous nanomaterials

Abstract

A preparation method for 3D printing femoral heads with customizable regenerative porous nanomaterials. The image data of the femoral head was obtained by CT scanning, and a three-dimensional model suitable for transplanted joints was established according to the CT image data. Metal nanocomposites and β-tricalcium phosphate-polypyrrole-biotin composite materials were used as the matrix materials of the femoral head respectively, and body-centered cubic Type porous structure is printed layer by layer, and then add icariin-biotin-polylactic acid microspheres for ball-carrying treatment, and the surface is covered with bioceramic coating. The bone printed by the invention is conducive to the growth of bone tissue and promotes growth The entry of factors, etc., can improve the drug loading capacity and sustained release performance, and has good mechanical properties and stability.

Description

technical field [0001] The invention designs a medical implant prosthesis, in particular to a custom-made and reproducible multi-component porous multilayer nanocomposite 3D printed hip joint femoral head. Background technique [0002] The hip joint is one of the important joints to maintain the daily activities of the human body, but it is also easy to damage and cause diseases. At present, hip replacement is an effective means to treat hip joint diseases. In recent years, with the development of 3D printing technology, scholars There has been great interest in the optimization design of artificial hip joint prosthesis. Many experts and scholars have made outstanding contributions to the development of artificial hip joint and made remarkable achievements. Artificial hip joint prosthesis requires good Biocompatibility, flexibility, load carrying capacity, stability and low friction and wear. With the continuous progress of material science and biomechanics, great breakthro...

AI Technical Summary

Problems solved by technology

[0021] The purpose of the present invention is to provide a method for preparing a 3D printed femoral head with customizable regenerative porous nanomaterials, which solves the problems of low utilization rate of artificial bone components and insufficient strength, toughness and wear resistance of the femoral head. The materials used in the structure can stimulate the repair and growth of bone cells, so that the product can meet the affinity of human bones while reducing the stress concentration and stress shielding of implants. The products customized and printed by 3D methods are more in line with the characteristics of human bones. The existence of its porous structure not only ensures the mechanical properties but also realizes the secondary growth of bones

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