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Composition for improving scar hyperplasia and hyperpigmentation in skin repair process

A technology for improving skin and pigmentation, applied in skin diseases, drug combinations, pharmaceutical formulations, etc., can solve problems such as convenient drug application and fast drug absorption

Pending Publication Date: 2021-05-18
重庆玛恩生物技术研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a prescription for improving scar hyperplasia and pigmentation in the process of skin repair, and to solve the technical problem of "failure to combine convenient drug application and fast drug absorption" in the prior art

Method used

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  • Composition for improving scar hyperplasia and hyperpigmentation in skin repair process
  • Composition for improving scar hyperplasia and hyperpigmentation in skin repair process
  • Composition for improving scar hyperplasia and hyperpigmentation in skin repair process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A prescription for improving scar hyperplasia and pigmentation in the process of skin repair. Its raw materials are 1.5 parts of asiaticoside, 0.5 parts of heparin sodium, 1 part of allantoin, 0.05 parts of Clostridium histolyticum collagenase, 78.5 parts of water, 3 parts of β-glucan, (composition of 1 part of glycerin, 1 part of propylene glycol, 0.5 parts of glycerin polymethacrylate and 0.5 parts of acrylic (ester) copolymer) 3 parts, acryloyl dimethyl 2 parts of ammonium taurate / VP copolymer, 0.2 parts of xanthan gum, 0.04 parts of disodium EDTA, 1 part of lecithin, 0.2 parts of centipede extract, 0.3 parts of toad extract, 1 part of ceramide, (1,2 - 0.3 parts of hexanediol, 0.5 parts of caprylyl hydroxyguanidine, 0.4 parts of 1,3-propanediol) 1.2 parts, 4.5 parts of silicone, 4 parts of 1,2-pentanediol, 0.5 parts of panthenol and lactic acid Bacteria consists of 2 parts.

[0026] The steps of preparing the gel medicine by formula in the present embodiment are as ...

Embodiment 2

[0034] A prescription for improving scar hyperplasia and pigmentation in the process of skin repair. Its raw materials are 2 parts of asiaticoside, 0.6 parts of heparin sodium, 1.5 parts of allantoin, 0.5 parts of Clostridium histolyticum collagenase, 72 parts of water, 3.5 parts of β-glucan, 5 parts of glycerin polymethacrylate, 3 parts of ammonium acryloyldimethyl taurate / VP copolymer, 0.3 parts of xanthan gum, 0.06 parts of disodium EDTA, eggs 3 parts of phospholipids, 0.3 parts of centipede extract, 0.4 parts of toad extract, 3 parts of ceramide, 4.8 parts of silicone.

[0035] The steps of preparing the gel medicine by formula in the present embodiment are as follows:

[0036] Step 1, heat the water to 90-100°C, keep it for 30 minutes, add EDTAA disodium after cooling to 30-35°C and stir evenly until no powder aggregates condense to obtain phase B. The vacuum degree during the stirring process is ≦-0.06MPa, Stirring speed is 50rpm;

[0037] Step 2: Under vacuum conditio...

Embodiment 3

[0043] A prescription for improving scar hyperplasia and pigmentation in the process of skin repair. Its raw materials are 2 parts of asiaticoside, 0.6 parts of heparin sodium, 1.5 parts of allantoin, 0.5 parts of Clostridium histolyticum collagenase, 70 parts of water, 3.5 parts of β-glucan, 5 parts of glycerin polymethacrylate, 3 parts of ammonium acryloyldimethyl taurate / VP copolymer, 0.3 parts of xanthan gum, 0.06 parts of disodium EDTA, nerve Composed of 3 parts of amide, 3 parts of lecithin, and 4.3 parts of silicone.

[0044] The steps of preparing the gel medicine by formula in the present embodiment are as follows:

[0045] Step 1, heat the water to 90-100°C, keep it for 30 minutes, add EDTAA disodium after cooling to 30-35°C and stir evenly until no powder aggregates condense to obtain phase B. The vacuum degree during the stirring process is ≦-0.06MPa, Stirring speed is 50rpm;

[0046] Step 2: Under vacuum conditions, mix 3 parts of ammonium acryloyldimethyltaurat...

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Abstract

The invention provides a composition for improving scar hyperplasia and hyperpigmentation in a skin repair process. The composition comprises the following raw materials: asiaticoside, heparin sodium, allantoin and indispensable auxiliary materials, and the composition further comprises the following raw materials in parts by weight: 0.03-0.5 part of clostridium histolyticum collagenase. By adopting the composition for improving the scar hyperplasia and hyperpigmentation in the skin repair process, scar tissue can be quickly softened, the drug can be quickly absorbed under the condition of realizing quick application operation of the drug, and acne pits and depression scars can also be improved.

Description

technical field [0001] The invention relates to a medicine for treating scars, in particular to a prescription (medicine prescription) for improving scar hyperplasia and pigmentation in the skin repair process. Background technique [0002] In the prior art: document CN105434195A discloses a composition with the function of removing acne and inhibiting the formation of acne scars, including A component and B component, and A component includes the following raw materials in parts by weight: 0.1-1 part of phytosterol, spike flower 0.1-1 part of vitex oil, 0.1-1 part of bisabolol and 0.1-1 part of stearyl glycyrrhetinate; component B includes the following raw materials in parts by weight: 0.1-1 part of phloretin, betaine water 0.1-2 parts of sylate, 0.5-5 parts of acetylglucosamine, 0.05-1 part of heparin sodium and 0.1-1 part of asiaticoside; the weight ratio of component A and component B is 0.4-4:0.85- 10; Document CN103356693A discloses a compound low-molecular-weight he...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/48A61P17/02A61K31/7024A61K31/4166A61K31/727
CPCA61K38/4886A61K31/7024A61K31/4166A61K31/727A61P17/02A61K2300/00
Inventor 周欢
Owner 重庆玛恩生物技术研究院有限公司
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