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Biological agent for preventing and relieving joint sub-health and preparation method thereof

A biological preparation and health technology, applied in the direction of medical preparations containing active ingredients, medical raw materials derived from ferns/filamentous plants, anti-inflammatory agents, etc., can solve low back pain without good curative effect, arthritis is not good Many, single indications and other problems

Inactive Publication Date: 2021-09-03
东莞市容大生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Ointments commonly used in the prevention and treatment of arthritis include Fengshitie and Shangshizhipain Ointment. These plasters have better effects for different cases, but they have the disadvantage of single main function, especially for the treatment of waist pain caused by bone hyperplasia. No good treatment for leg pain
At present, there are not many topical biological preparations on the market that use the concept of integrated traditional Chinese and Western medicine to prevent and treat arthritis, and the effect is difficult to determine.

Method used

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  • Biological agent for preventing and relieving joint sub-health and preparation method thereof
  • Biological agent for preventing and relieving joint sub-health and preparation method thereof
  • Biological agent for preventing and relieving joint sub-health and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] The total amount of raw materials is 100 kg. in,

[0068] Phase A materials: 9.0 kg of glycerin, 6.0 kg of propylene glycol, and 2.0 kg of butanediol;

[0069] Phase B materials: 5 kg of sorbitan sesquioleate, 1.2 kg of isosteareth-20, 2.0 kg of isohexadecane, 1.6 kg of sorbitan stearate, 2.3 kg of sorbitan isostearate , Frankincense Oil 0.7 kg, Ceylon Cinnamon Leaf Oil 0.05 kg, Lemongrass Leaf Oil 0.02 kg, Polysorbate-60, 0.8 kg, Sodium Stearoyl Glutamate 0.4 kg, Hydroxyethyl Acrylate / Acryloyl Di 0.3 kg of sodium methyl taurate copolymer, 1.1 kg of acrylic acid (ester) copolymer, 0.05 kg of aluminum magnesium silicate, 0.1 kg of methyl paraben, and 0.02 kg of ethyl paraben;

[0070] Phase C material: 2.0 kg of butanediol, 0.05 kg of tetrahydropiperine;

[0071] Phase D materials: 3.1 kg of Herba chinensis extract, 6.2 kg of Passepartout extract, 4.0 kg of ginger root extract, 5.3 kg of Morinda officinalis fruit extract, 0.15 kg of camphor, 2.5 catties of methyl sali...

Embodiment 2

[0083] The formula of embodiment 2 is identical with embodiment 1, and the difference between embodiment 2 and embodiment 1 is only preparation technology, and the preparation technology of embodiment 2 is as follows:

[0084] (1) Weigh each phase raw material by weight percentage;

[0085] (2) Mix the materials of phase A, add them to the water phase pot, heat to 80°C, and sterilize at a constant temperature for 25 minutes to obtain the water phase materials;

[0086] (3) Mix the materials of phase B, add them into the emulsification pot, heat to 75°C, and sterilize at a constant temperature for 20 minutes to obtain the oil phase materials;

[0087] (4) Under vacuum stirring state, pump 1 / 2 volume of the water phase material obtained in step (2) into the emulsification pot and mix with the oil phase material obtained in step (3), and homogenize at 70°C for 3 minutes, and then sterilize at a constant temperature 25 minutes;

[0088] (5) Heat and dissolve the C-phase material...

Embodiment 3

[0092] The total amount of raw materials is 100 kg. in,

[0093] Phase A materials: 1.0 kg of glycerin, 9.8 kg of propylene glycol, and 4.5 kg of butanediol;

[0094] Phase B material: Sorbitan sesquioleate 3.5 kg, Isosteareth-20 3.0 kg, Isohexadecane 2.3 kg, Sorbitan stearate 1.5 kg, Sorbitan isostearate 2.0 kg , Frankincense Oil 3.2 kg, Ceylon Cinnamon Leaf Oil 0.6 kg, Lemongrass Leaf Oil 0.5 kg, Polysorbate-60 1.0 kg, Sodium Stearoyl Glutamate 0.8 kg, Hydroxyethyl Acrylate / Acryloyl Dimethicone 0.1 kg of sodium taurate copolymer, 0.05 kg of acrylic acid (ester) copolymer, 0.01 kg of aluminum magnesium silicate, 0.01 kg of methyl paraben, and 0.01 kg of ethyl paraben;

[0095] Phase C material: 3.0 kg of butanediol, 4.0 kg of tetrahydropiperine;

[0096] Phase D materials: 2.0 kg of Herba chinensis extract, 4.2 kg of Passepartout extract, 5.0 kg of ginger root extract, 3.0 kg of Morinda officinalis fruit extract, 0.01 kg of camphor, 0.1 catties of methyl salicylate, ascorb...

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Abstract

The invention discloses a biological agent for preventing and relieving joint sub-health and a preparation method thereof, and belongs to the technical field of biological agents. The biological agent of the present invention contains a plurality of bioactive components and a plurality of active ingredients of Chinese herbs. The bioactive components comprise S-adenosylmethionine, sodium hyaluronate, sodium chondroitin sulfate, vitrin and acetyl glucosamine, can prevent decomposition of proteoglycan by enzyme, provide exogenous hyaluronic acid for human joints, activate synthesis of mucopolysaccharide in the body, and promote synthesis of hyaluronic acid and collagen and cartilage regeneration. The bioactive components can improve content of hyaluronic acid in the body, reduce cartilage loss and maintain morphology of cartilage and synovial fluid. The active ingredients of Chinese herbs comprise fructus liquidambaris extract, herba lycopodii extract, fructus morinda citrifolia and ginger root extract, and have the effects of relaxing tendons and activating collaterals, promoting blood circulation to remove blood stasis, improving local microcirculation and relieving pain. According to the biological agent, Chinese medicines and western medicines are combined to fundamentally prevent and relieve joint inflammation.

Description

technical field [0001] The invention relates to the technical field of biological preparations, in particular to a biological preparation for preventing and alleviating joint sub-health and a preparation method thereof. Background technique [0002] Arthritis generally refers to an inflammatory disease that occurs in human joints and their surrounding tissues and is caused by inflammation, infection, degeneration, trauma or other factors. According to the etiology, arthritis can be divided into osteoarthritis, rheumatoid arthritis, ankylosing arthritis, reactive arthritis, gouty arthritis, rheumatoid arthritis, infectious arthritis, etc. There are a large number of arthritis patients in my country, mostly in middle-aged and elderly people, but also in young people. The disease is prone to occur in the hands, wrists, feet, etc., with redness, swelling, heat, pain, and dysfunction in the early stage, and joint deformity and even disability in the late stage. 80% of the elder...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P19/02A61P19/08A61P29/00A61P19/06A61P31/00A61K31/737A61K31/728A61K31/7008A61K31/35A61K31/125A61K31/085A61K31/045
CPCA61K36/11A61K36/185A61K36/9068A61K36/746A61K31/125A61K31/045A61K31/737A61K31/728A61K31/7008A61K31/35A61K36/54A61K36/324A61K36/899A61K31/085A61K9/0014A61P19/02A61P19/08A61P29/00A61P19/06A61P31/00A61K2300/00
Inventor 张泽奇杨平顺韩春月李利芳黄纲富马莉娟
Owner 东莞市容大生物科技有限公司
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