Preparation method of acesulfame potassium

Abstract

The invention discloses a preparation method of acesulfame potassium, which comprises the following steps: a salt forming step: separating a sulfonation cyclization product solution into an organic phase and an inorganic phase, and adding an ethanol solution of potassium ethoxide into the organic phase for salt forming reaction, wherein the sulfonation cyclization product solution is obtained by hydrolyzing a product obtained by cyclization addition of acetoacetamide-N-sulfonic acid triethylamine salt and sulfur trioxide; and a washing step: after the salt forming reaction is finished, filtering to obtain a solid product, and washing the solid product with ethanol to obtain a crude acesulfame potassium product. According to the invention, the content of inorganic impurities in the acesulfame potassium crude product is greatly reduced, and the purity of the final product acesulfame potassium is remarkably improved; the subsequent process of the acesulfame potassium crude product is simplified, and the purification cost of the acesulfame potassium crude product is reduced; and the yield of acesulfame potassium can be improved.

Description

technical field [0001] The invention belongs to the technical field of fine chemical manufacturing, and in particular relates to a preparation method of acesulfame potassium. Background technique [0002] Acesulfame potassium (acesulfame potassium), also known as AK sugar, is a widely used sugar substitute food additive. Its appearance is white crystalline powder. As an organic synthetic salt, its taste is similar to sugarcane, and it is easily soluble in water. , Slightly soluble in alcohol, its chemical properties are stable, and it is not easy to break down and fail; it does not participate in the body's metabolism and does not provide energy; it has high sweetness and low price; it has no cariogenicity; it has good stability to heat and acid. [0003] At present, in the synthesis of acesulfame potassium, the diketene-sulfur trioxide method is widely used. The specific reaction steps include: reacting sulfamic acid with amine to form amine sulfamic acid salt, and then rea...

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Problems solved by technology

[0003] At present, in the synthesis of acesulfame potassium, the diketene-sulfur trioxide method is generally used, and the specific reaction steps include: reacting sulfamic acid with amine to form amino sulfonic acid amine salt, then react sulfamic acid amine salt with diketene to form acetyl acetamide salt; in the presence of sulfur trioxide, acetyl acetamide salt undergoes cyclization reaction to form cyclic sulfur trioxide adduct; The cyclic compound is hydrolyzed to obtain a hydrolyzate (ASH); then the hydrolyzate is usually treated with potassium hydroxide or potassium hydroxide aqueous solution to obtain acesulfame potassium (ASK), such as Chinese patent CN111228854A, Chinese patent CN1062560C and Chinese patent CN111377883A, etc., using Potassium hydroxide or potassium hydroxide aqueous solution carries out salt-forming reaction, and there are many problems, as in the process of separating, also there is a large amount of inorganic components in the product of direct precipitation, such as potassium fluoride, potassium sulfate etc., the product purity is difficult to further improve increase, causing the problem of low purity of the final product acesulfame potassium

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