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Hair dye containing silicon dioxide nanoparticles loaded with dihydroxyindole carboxylic acid

A technology of oxindole carboxylic acid and silicon dioxide, applied in skin care preparations, medical preparations containing active ingredients, cosmetics, etc., can solve the problems of poor hair dyeing effect, achieve good biocompatibility, particle size Small, maintains the effect of dyeing effect

Active Publication Date: 2021-10-22
绍兴孚原生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the above-mentioned prior art, the present invention provides a hair dye containing silica nanoparticles loaded with dioxindole carboxylic acid to solve the technical problem of poor hair dyeing effect of existing hair dyes

Method used

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  • Hair dye containing silicon dioxide nanoparticles loaded with dihydroxyindole carboxylic acid
  • Hair dye containing silicon dioxide nanoparticles loaded with dihydroxyindole carboxylic acid
  • Hair dye containing silicon dioxide nanoparticles loaded with dihydroxyindole carboxylic acid

Examples

Experimental program
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Effect test

Embodiment 1

[0042] A hair dye containing silica nanoparticles loaded with dioxindole carboxylic acid, comprising agent A and agent B; wherein, agent A is composed of the following components in mass percentage:

[0043] Silica nanoparticles loaded with 5,6-dihydroxyindole carboxylic acid 9%, isohexadecane 3%, PPG-14 butyl ether 3%, oleic acid 7%, glycerin 11%, butanediol 12%, Sodium sulfite 4%, ethylhexyl methoxycinnamate 8%, cetyl PEG 6% and orange pigment 0.5%, and the balance is deionized water.

[0044] The silica nanoparticles loaded with 5,6-dihydroxyindole carboxylic acid in agent A are prepared through the following steps:

[0045] S1: Co-dissolve silica nanoparticles and dioxindole carboxylic acid as 5,6-dihydroxyindole carboxylic acid in methanol at a mass ratio of 1:1, and treat with ultrasonic pulses at a frequency of 40KHz at 30°C After 10 minutes, the product solution was obtained; the pulse mode of ultrasonic pulse treatment was 1.6s on / 0.4s off;

[0046] S2: Centrifuge t...

Embodiment 2

[0059] A hair dye containing silica nanoparticles loaded with dioxindole carboxylic acid, comprising agent A and agent B; wherein, agent A is composed of the following components in mass percentage:

[0060] Silica nanoparticles loaded with 5,6-dihydroxyindole carboxylic acid 2%, isohexadecane 3%, PPG-14 butyl ether 1%, oleic acid 8%, glycerin 8%, butanediol 12%, 4% sodium sulfite, 8% ethylhexyl methoxycinnamate, 4% cetyl PEG and 0.5% orange pigment, and the balance is deionized water.

[0061] The silica nanoparticles loaded with 5,6-dihydroxyindole carboxylic acid in agent A are prepared through the following steps:

[0062] S1: Co-dissolve silica nanoparticles and 5,6-dihydroxyindole carboxylic acid in methanol at a mass ratio of 1:2, and conduct ultrasonic pulse treatment at a frequency of 40KHz at 32°C for 8 minutes to obtain a product solution; ultrasonic The pulse mode of pulse processing is 1.6s on / 0.4s off;

[0063] S2: Centrifuge the product solution at a rate of 1...

Embodiment 3

[0076] A hair dye containing silica nanoparticles loaded with dioxindole carboxylic acid, comprising agent A and agent B; wherein, agent A is composed of the following components in mass percentage:

[0077] Silica nanoparticles loaded with 5,6-dihydroxyindole carboxylic acid 14%, isohexadecane 1%, PPG-14 butyl ether 3%, oleic acid 6%, glycerin 12%, butanediol 8%, Sodium sulfite 6%, ethylhexyl methoxycinnamate 6%, cetyl PEG 6% and orange pigment 0.5%, and the balance is deionized water.

[0078] The silica nanoparticles loaded with 5,6-dihydroxyindole carboxylic acid in agent A are prepared through the following steps:

[0079] S1: Co-dissolve silica nanoparticles and 5,6-dihydroxyindole carboxylic acid in methanol at a mass ratio of 1:1, and process ultrasonic pulses at a frequency of 40KHz for 12 minutes at 28°C to obtain a product solution; ultrasonic The pulse mode of pulse processing is 1.6s on / 0.4s off;

[0080] S2: Centrifuge the product solution at a rate of 16000 rp...

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Abstract

The invention discloses a hair dye containing silicon dioxide nanoparticles loaded with dihydroxyindole carboxylic acid. The hair dye comprises an agent A and an agent B, the agent A is prepared from silicon dioxide nanoparticles loaded with dihydroxyindole carboxylic acid, isohexadecane, PPG-14 butyl ether, oleic acid, glycerol, butanediol, sodium sulfite, ethylhexyl methoxycinnamate, cetyl PEG (Polyethylene Glycol) and orange pigment; the agent B comprises hydrogen peroxide, oleyl alcohol, oleic acid, propylene glycol, isopropanol, sodium dodecyl sulfate and hydrated silica. The hair dye disclosed by the invention is good in dyeing effect, can still keep a relatively good dyeing effect after being washed for multiple times, has excellent anti-ultraviolet performance, and can effectively solve the technical problem that the existing hair dye is poor in hair dyeing effect.

Description

technical field [0001] The invention relates to a hair dye, in particular to a hair dye containing silica nanoparticles loaded with dioxindole carboxylic acid. Background technique [0002] In today's society, hair dyeing as a way of image change is very common among the elderly, middle-aged, and young people. Hair dyes and other hair dye products used in the hair dyeing process are becoming more and more popular. Most of the hair dyes currently on the market are aniline materials, which are not only toxic but also have abnormal odors and can cause cancer. Melanin is a biological pigment that is present in everyone's body. It is formed by a series of chemical reactions of tyrosine or 3,4-dihydroxyphenylalanine. It is the presence of melanin that gives skin and hair its color. Dopa is actually the precursor of melanin, which is oxidized by tyrosine to release melanin. The partial oxidation product of dopamine, dioxindole carboxylic acid, is similar to 5,6-dioxindole but is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/86A61K8/22A61K8/23A61K8/25A61K8/34A61K8/49A61Q5/10A61Q17/04
CPCA61K8/86A61K8/492A61K8/25A61K8/22A61K8/23A61K8/345A61Q5/10A61Q17/04A61K2800/413A61K2800/82A61K2800/4324A61K2800/56
Inventor 李昊天郭万才
Owner 绍兴孚原生物科技有限公司
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