High-purity separation process of emodin

Abstract

The invention discloses a high-purity separation process of emodin, relates to the field of separation processes of emodin, and aims to solve the problem that in the prior art, used reagents are toxic solvents and threaten human bodies and environments. According to the technical scheme, enzyme is added into a mixture of distilled water and polygonum cuspidatum powder, external cell walls of the polygonum cuspidatum powder can be decomposed, so that the emodin in the polygonum cuspidatum powder can be extracted more easily, and the yield of the emodin is increased; ethyl acetate is used for extraction, emodin can be separated from the mixture, ethyl acetate is free of toxicity and pungent smell, and personnel health and environmental safety are protected; distilled water is used for elution, so that water-soluble impurities can be removed, and the product purity is improved; the emodin crude extract obtained through filtration is subjected to chromatography on a chromatographic column, then elution, reduced pressure distillation and recrystallization are conducted, alcohol is adopted as an eluent, the elution effect is good, the emodin yield is increased, pollution is avoided, separation is easy, and personnel health and environmental safety are further protected.

Description

technical field [0001] The invention relates to the field of emodin separation technology, in particular to a high-purity separation technology of emodin. Background technique [0002] Emodin is an organic compound with the chemical formula C 15 h 10 o 5 , Orange-yellow long needle-like crystal, crystallizes orange in acetone, crystallizes yellow in methanol, melting point 256-257°C, has special reaction to anthraquinone, almost insoluble in water, soluble in ethanol and alkali solution. [0003] Emodin is the dry rhizome and root of Polygonum cuspidatum. The rhizome of Rhubarb palmatum belongs to plant medicine. [0004] The physiological activity of emodin determines that it can be used not only in medical treatment, but also in health care and daily chemicals. For example, some people use it in hair care and skin care products, and some people incorporate it into natural pigments. Abroad, people use it as a laxative. [0005] Clinically, pure emodin is used to treat...

AI Technical Summary

Problems solved by technology

[0009] The existing emodin extraction uses a large amount of solvents such as benzene for extraction. This method is not only expensive, but also uses volatile and toxic solvents, which pose a threat to people and the environment.