Ophthalmic preparation for treating macular edema, optic neuritis and non-infectious entophthalmia through eye drop administration

An ophthalmic preparation and preparation technology, applied in the direction of medical preparations with non-active ingredients, non-central analgesics, medical preparations containing active ingredients, etc., can solve the problems of poor drug delivery, difficulty in effectively treating fundus diseases, and difficult Taking into account safety and effectiveness and other issues, to achieve the effect of small dosage, avoid systemic toxic and side effects, and increase medical compliance
CN113797162AActive Publication Date: 2021-12-17CHENGDU RUIMU BIO PHARM TECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
CHENGDU RUIMU BIO PHARM TECH CO LTD
Publication Date
2021-12-17

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Abstract

The invention provides an ophthalmic preparation for treating macular edema, optic neuritis and non-infectious entophthalmia. The ophthalmic preparation is composed of an active ingredient for treating eye diseases and an ophthalmic preparation carrier or auxiliary material; the active ingredientfor treating the eye diseases is a glucocorticoid medicine and / or a non-steroidal medicine; the ophthalmic preparation carrier or auxiliary material comprises the following ingredients: a surfactant, an ionic polymer and a solvent, or the ophthalmic preparation carrier or auxiliary material contains the following ingredients: povidone with low polymerization degree, povidone with medium polymerization degree and a solvent. The ophthalmic preparation can carry (wrap) the glucocorticoid and / or the non-steroidal medicines to penetrate through the anterior segment of the eye and be conveyed to the posterior segment of the eye to treat the macular edema, the optic neuritis and the non-infectious entophthalmiain an eye drop administration mode, and the ophthalmic preparation has extremely excellent clinical use value and very positive social significance.
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Description

technical field

[0001] The invention belongs to the field of ophthalmic drugs, in particular to an ophthalmic preparation for treating macular edema, optic neuritis and non-infectious endophthalmitis by eye drops. Background technique

[0002] There are many patients with fundus diseases, and the number of patients in China alone has exceeded tens of millions. With the aging society and the popularization of electronic products, the incidence rate will increase year by year; common fundus diseases include diabetic macular edema, diabetic retinopathy, age Related macular degeneration, retinal vein occlusion, pathological myopia, geographic atrophy, eye tumors, endophthalmitis, etc., may lead to vision loss or even blindness, seriously affecting people's quality of life. For example, about 6.8% of diabetic patients suffer from diabetic macular edema (DME), which is the main cause of blindness in diabetic patients (Urias et al., VisionResearch, V139:221-227, 2017; Mandal et al....

Claims

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