10 results about "Eye posterior segment" patented technology

The present invention relates to a microneedle for drug delivery to a posterior segment of the eye and a use thereof. The microneedle for drug delivery to a posterior segment of the eye of the present invention has the advantage of delivering a drug to the eye in a minimally invasive and efficient manner through an expansion mechanism by being inserted into the posterior segment of the eye. Therefore, the microneedle for drug delivery to a posterior segment of the eye of the present invention can be used in various ways to treat ocular complications by preventing backflow due to intraocular drug delivery, which is an existing limitation.

The present invention relates to means and methods to non-invasive ocular drug delivery technologies, particularly aimed at delivering pharmaceutically active ingredients (APIs) to the posterior segment of the eye.

This invention provides an ophthalmic optical device that eliminates the need to place a separate lens attachment between the objective lens and the eye under examination by changing the working distance between the objective lens and the eye under examination when observing the posterior segment and when observing the anterior segment. [Solution] In the ophthalmic optical device, when photographing the posterior segment of the eye under examination, a position conjugate to the vertical scanning unit is formed in the anterior segment of the eye under examination, and the scanning beam from the vertical scanning unit is focused on the posterior segment of the eye under examination. When photographing the anterior segment of the eye under examination, the working distance, which is the distance between the eye under examination and the objective lens, is greater than the working distance when photographing the posterior segment, and the scanning beam from the vertical scanning unit is focused on the anterior segment of the eye under examination. The scanning direction of the scanning beam by the vertical scanning unit is the same when photographing the posterior segment and when photographing the anterior segment.

To provide: a method for delivering an agent to a posterior segment of an eye; and an eye drop and a method for treating an ocular disease in a subject in need of treatment.SOLUTION: The method for delivering an agent to a posterior segment of an eye comprises administering a pharmaceutical composition comprising the agent and mesoporous silica nanoparticles to the eye, where the agent is loaded by mesoporous silica nanoparticles.SELECTED DRAWING: None

1. The name of the design product: ophthalmic surgical equipment. 2. The use of the design product: the design product is used for the surgical system of anterior and posterior segment of eye surgery, and ophthalmic cataract phacoemulsification and vitrectomy surgery. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention discloses an optical system and method for measuring the axial length of the eye, the optical system comprises an OCT light source module, an OCT imaging module, a posterior segment OCT sample arm module and an anterior segment fracture imaging assembly, the OCT light source module provides measuring light, the measuring light penetrates through the posterior segment OCT sample arm module and then enters the fundus of the human eye to be measured, and the anterior segment fracture imaging assembly is used for imaging the anterior segment fracture. The OCT imaging module receives the measuring light to obtain a posterior segment OCT image; the anterior segment fissure imaging assembly comprises an anterior segment fissure light source module, an anterior segment fissure imaging module and an anterior segment fissure imaging adjusting light path module, the anterior segment fissure light source module provides fissure light, and the fissure light penetrates through the anterior segment fissure imaging adjusting light path module and then is focused on the anterior segment of a person to be detected; the anterior segment fissure imaging module receives the fissure light to obtain an anterior segment fissure image; and respectively acquiring first optical path data and second optical path data by using the posterior segment OCT image and the anterior segment fracture image so as to calculate the axial length of the eye. According to the invention, the influence of eye movement of the to-be-measured eye is avoided, and the eye axis length measurement precision is improved.

The invention relates to application of polydopamine nanoparticles loaded with pharmaceutical active substances in preparation of drugs for treating posterior segment diseases of eyes, and belongs to the technical field of pharmaceutical preparations. According to the application of the polydopamine nanoparticles loaded with the pharmaceutical active substance in preparation of the medicine for treating the posterior ocular diseases, the polydopamine nanoparticles are solid polydopamine nanoparticles or mesoporous polydopamine nanoparticles, and the pharmaceutical active substance is the medicine for treating the posterior ocular diseases. According to the invention, the drug is loaded in the polydopamine nanoparticles, and the binding characteristic of polydopamine and melanin widely distributed in eye parts, especially fundus, is utilized, so that the transshipment capability of the drug to posterior eye segment tissues is enhanced in a non-invasive local administration manner, and the treatment effect on posterior eye segment diseases is improved; and the preparation method has a wide application prospect in local administration posterior segment drug delivery.

The invention relates to an ophthalmic liposomal formulation for topical use that improves paracellular penetration of therapeutic agents such as aflibercept in the eyeball. The formulation includes an optimised mixture of liposomes, non-ionic solubilisers and excipients to facilitate the transport of the drug through the cornea and the controlled release thereof in the posterior segment of the eye. The formulation uses liposomes as a transport system, maximising the ocular bioavailability of aflibercept by means of a synergic combination of emulsifiers and stabilisers, allowing efficient penetration through the corneal barrier and sustained release of the drug in the eye tissue.

1. The name of the design product: laser ophthalmic diagnostic instrument. 2. The use of the design product: for fixing human eye to carry out laser scanning imaging of anterior segment and posterior segment of eye. 3. The design points of the design product: in shape. 4. The picture or photo best indicating the design points: perspective view 1.

This invention relates to ophthalmic disease treatment agents comprising vascular endothelial growth factor (VEGF) receptor inhibitors in nanoparticle form, which have the property of remaining in the posterior segment of the eye when administered systemically.