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48 results about "Eye anterior segment" patented technology

The anterior segment or anterior cavity is the front third of the eye that includes the structures in front of the vitreous humour: the cornea, iris, ciliary body, and lens.

Eyeball tumor area real-time positioning system based on motion features of eyeball

The invention discloses an eyeball tumor area real-time positioning method based on motion features of an eyeball. The eyeball tumor area real-time positioning method comprises the following steps of extracting an eye anterior-segment tissue information, conducting calibration and three-dimensional reconstruction on the eye anterior-segment tissue information to obtain shifting parameters before and after eyeball motion, establishing a three-dimensional eyeball model based on a CT image, and establishing the coordinate relation between an eye anterior segment feature structure and an intraocular tumor position. According to the eyeball tumor area real-time positioning method, an anterior-segment image obtained through real-time OCT tracking is utilized, and then the tumor is accurately positioned in a radiation area through processing technologies including image reconstruction, registering and the like. The invention further discloses an imaging device for extracting the eye anterior-segment tissue information. The imaging device for extracting the eye anterior-segment tissue information comprises an OCT light source, a beam splitter, a sample arm, a reference arm and a feedback device. A real-time positioning tracking system provides in-vitro noninvasive positioning and can achieve the purposes of improving positioning accuracy and radiation dose and local control rate of the ocular tumor, decreasing surrounding normal radiation dose and injury and the like.
Owner:THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV

Angiography method applied to optical coherence tomography and OCT system

The invention relates to an angiography method applied to optical coherence tomography and an OCT system. Based on the frequency division thought, OCT interference fringes are decomposed into multiple wave number bands, and noise generated when shot tissue moves is lowered. After intensity images obtained after frequency division are acquired, an improved CM method is further adopted, the change degree of the intensity, calculated through the Pearson correlation coefficient, between adjacent continuously scanned cross-sectional images is calculated, and signals of blood vessels are enhanced. In combination with information of points adjacent to detection points, sensitivity to blood vessel detection is improved, sensitivity to eye movement is reduced, and the method is suitable for angiography of biological tissue with high scattering. The method can be used for angiography of anterior segment sclera or irises or other tissue in ophthalmology and can be applied to microvascular imaging of other portions of the human body.
Owner:WENZHOU MEDICAL UNIV

Multi-functional ophthalmic full-automatic measurement method and system

The invention discloses a multi-functional ophthalmic full-automatic measurement method and system. The multi-functional ophthalmic full-automatic measurement method comprises the steps that a three-dimensional movement control unit is adjusted to automatically adjust a probe assembly after a to-be-measured eye is monitored to be located right in front of an eye objective lens; a control device ina body module drives a first mobile control unit to control an anterior segment OCT insertion mirror to be inserted into an optical path or moved out of the optical path and adjust an optical path adjusting device; measurement light provided by the body module enters the to-be-measured eye and is focused in the anterior segment of the to-be-measured eye or the fundus of the to-be-measured eye soas to return an anterior segment optical signal or a posterior segment optical signal to be transmitted to the body module; and the body module provides reference light and can utilize the reference light to interfere with the anterior segment optical signal or the posterior segment optical signal and collect the anterior segment interference optical signal or the posterior segment interference optical signal obtained through interference so as to respectively collect an anterior segment OCT image or a posterior segment OCT image of the eye to be measured. The measurement convenience can be improved, and the measurement accuracy can be improved.
Owner:SHENZHEN CERTAINN TECH CO LTD

Anterior-posterior segment frequency domain optical coherence tomography system

ActiveCN110755031ARealize the imaging function of anterior segmentOthalmoscopesFrequency domain optical coherence tomographyRetina
The invention relates to an anterior-posterior segment frequency domain optical coherence tomography system, in the anterior segment / posterior segment imaging process, an FD-OCT system adopts the sameoptical path hardware, and conversion of a scanning focus range of probe light from the fundus retina to the cornea is achieved by internally adjusting the position of a scanning conversion assemblyspecially designed in a sample arm. In the anterior segment / posterior segment imaging process of the eye, the frequency domain optical coherence tomography imaging system adopts the same optical pathhardware; by internally adjusting the position of the scanning conversion assembly specially designed in the sample arm, conversion of the scanning focus range of the probe light from the fundus retina to the cornea is achieved, and therefore the anterior segment and posterior segment frequency domain optical coherence tomography system can have the anterior segment imaging function without addingthe FD-OCT system hardware. According to the invention, an anterior segment imaging function of the posterior segment frequency domain optical coherence tomography system can be realized without adding an additional imaging objective lens, and the use and detection operation process and the system structure are simplified.
Owner:天津迈达医学科技股份有限公司

Anterior segment sectional image feature extraction method based on machine vision

The invention discloses an anterior segment sectional image feature extraction method based on machine vision, and the method comprises the following steps: collecting an anterior segment sectional image under low-illumination illumination; enhancing the contrast of the anterior segment sectional image by adopting a Retinex algorithm; performing Gaussian filtering to remove noise generated after the step S2; finding a potential corneal region through binarization and blob shape analysis; roughly positioning the edges of the front and rear surfaces of the cornea in the potential cornea region by using a gradient maximum method; determining sub-pixel precision boundaries of the front surface and the rear surface of the cornea through a Gaussian fitting positioning method; according to the solved sub-pixel precision boundaries of the front and rear surfaces of the cornea, finding initial points of the iris and the crystalline lens, and obtaining accurate boundary values of the front and rear surfaces of the cornea, the front surface of the crystalline lens and the front surface of the iris through tracking. The invention has the following advantages and effects that high-precision processing can be performed on the image in a low-illumination imaging mode, and the matching degree and the comfort degree of a patient can be greatly improved.
Owner:THE EYE HOSPITAL OF WENZHOU MEDICAL UNIV

Image analysis system for ophthalmological anterior chamber angle anterior segment

The invention discloses an image analysis system for an ophthalmological anterior chamber angle anterior segment, and belongs to the field of image analysis. The image analysis system for the ophthalmological anterior chamber angle anterior segment includes a fixing plate, an outer shell is fixedly connected to the rear side of the upper surface of the fixing plate, a rotating plate is rotatably connected to the inner side surface of the outer shell, a center lens is fixedly installed at the inner center of the rotating plate, side lenses are fixedly installed to the outer side of the outer surface of the rotating plate, and the side lenses are uniformly distributed to the outer side surface of the center lens; and connecting rods are fixedly connected to two ends of the front side surfaceof the rotating plate, the outer surfaces of the connecting rods are slidingly connected to the surfaces of the two sides of the interior of the outer shell, the other end of each connecting rod is fixedly connected with an adjustment ring, and a friction rubber ring is fixedly adhered to the inner side surface of each adjustment ring. The convenience and stability during use can be greatly improved, and the accuracy and high efficiency can be ensured.
Owner:SHANDONG FIRST MEDICAL UNIV & SHANDONG ACADEMY OF MEDICAL SCI

Pharmaceutical compositions for preventing glucocorticoid-induced corneal or skin thinning

The present invention relates to method and pharmaceutical compositions for preventing glucocorticoid-induced corneal or skin thinning. In particular, the present invention relates to a mineralocorticoid receptor antagonist for topical use in a method for preventing or reducing glucocorticoid-induced corneal or skin thinning in a subject in need thereof. The invention also relates to a topical pharmaceutical composition comprising an amount of at least one glucocorticoid and an amount of at least one mineralocorticoid receptor antagonist or inhibitor of MR expression for use in a method for treating an inflammatory skin disease or an inflammatory disease of the cornea or of the anterior segment of the eye in a subject in need thereof.
Owner:유니베르시떼 파리 시테 +3

Full femtosecond laser system for eyeball spin correction

ActiveCN109984883ASolve the problem that the eyeball spin cannot be correctedSolve problems such as the deviation of the astigmatism cutting axis, which affects the quality of the operationLaser surgeryEyepieceFemto second laser
The invention discloses a full femtosecond laser system for eyeball spin correction. The full femtosecond laser system for eyeball spin correction comprises an eye anterior segment biological measurement unit, a spin control unit, a patient posture adjusting unit, a horizontal axial position marking unit, a negative pressure suction unit and a femtosecond laser unit, wherein the eye anterior segment biological measurement unit is used for collecting eyeball position information when a patient sits and sending the eyeball position information to the spin control unit; the spin control unit is used for collecting the eyeball position information of the patient in the supine position, comparing the eyeball position information of the patient in the supine position with the eyeball position information of the patient in the sitting position so as to obtain the eyeball spin information, and sending the eyeball spin information to the patient posture adjusting unit; the patient posture adjusting unit is used for adjusting the posture of the patient in the supine position according to the eyeball spin information, so that an absolute value of an eyeball spin angle is smaller than 1 degree; the horizontal axial position marking unit is used for completing horizontal axis marking of an operative eye in the sitting position according to a horizontal projection line; the negative pressuresuction unit is used for carrying out negative pressure suction and adjustment on the eyeball, so that a horizontal axis mark of the operative eye in the sitting position is parallel to a horizontalline of a cross mesh of an eyepiece; the femtosecond laser unit is used for carrying out femtosecond laser cutting. The full femtosecond laser system for eyeball spin correction solves the problem that an existing full femtosecond laser system fails to correct eyeball spin.
Owner:刘泉

OCT-based eye axis measurement method and device

The invention discloses an OCT-based eye axis measurement method and device. The method comprises the following steps: performing self-inspection on an optical path of eye axis measurement by utilizing a reference position calibration method, so that a posterior segment optical path adjusting device is located at a reference position; and adjusting the eye axis measurement device to collect the OCT two-dimensional tomography results of the cornea and the retina to be measured at the same time, and then measuring the eye axis length of the eye to be measured according to the OCT two-dimensional tomography results of the cornea and the retina to be measured and the displacement of the posterior segment optical path adjusting device. The eye axis measurement device is used for implementing the eye axis measurement method, and OCT two-dimensional tomography is performed on the anterior segment and the posterior segment of the eye to be measured at the same time. According to the invention, the anterior segment and the posterior segment can be synchronously focused, synchronous and clear imaging of the anterior segment and the posterior segment can be further realized, and the reference position of the optical path of the sample arm can be quickly calibrated before each eye axis measurement by using a reference position calibration method, so that the accuracy of eye axis measurement can be improved.
Owner:ZHEJIANG UNIV +1

A Method for Analyzing Anterior Segment Morphology

ActiveCN108814544BReduce complexityNo spatial optical aberrationsGonioscopesEyepieceAnterior cornea
The invention relates to an anterior segment morphology analysis method, wherein the data acquisition system used by the method comprises a monitoring module, a light splitting module, an eyepiece, anoptical coherence tomography module and a computer. A two-dimensional galvanometer non-contact optical scan is performed on a human eye to collect a three-dimensional data block of the anterior segment of the eye, and the method comprises the following steps of: acquiring the three-dimensional data block of the anterior segment, performing edge extraction on the data block, carrying out rough alignment and fine alignment, fitting, re-sampling and calculating a slope, and finally obtaining the tissue morphology analysis result of the anterior segment, including an anterior segment sectional image, a corneal anterior surface topographic map, a corneal posterior surface topographic map, a corneal thickness map, a crystalline anterior surface topographic map, a crystalline posterior surface topographic map, a crystalline thickness map, a corneal three-dimensional image, a chamber-angle three-dimensional image, an iris three-dimensional image, and a crystalline three-dimensional image. Byusing the method, the complexity of the algorithm is reduced, the measurement accuracy is ensured. The method is non-invasive, has no stimulation, and is easily accepted by patients.
Owner:TIANJIN SUOWEI ELECTRONICS TECH
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