37 results about "Eye anterior segment" patented technology

A glaucoma treatment apparatus including an imaging device capable of imaging the anterior segment of the eye, a treatment laser, an algorithm programmed to determine a location and a cross sectional area of a treatment based on a customized anatomy of the anterior segment of the eye including the trabecular meshwork (TM), the Schlemm's Canal (SC) and collector channels (CCS), obtained from pre-operative images of the anterior segment of the eye, a pre-operative intraocular pressure (IOP) level and a target IOP reduction as an inputs, and a processor configured to actuate the apparatus to create an outflow channel with a cross-sectional area and location or multiple outflow channels with multiple cross-sectional areas and locations from the anterior chamber (AC) to the SC across the TM, as determined by the algorithm to achieve the target intraocular pressure (IOP) reduction. Also disclosed is a method of reducing intraocular pressure in an eye.

[Problem] To provide a technology with which it becomes more likely to be able to select a posterior chamber phakic intraocular lens having a size suitable for a subject's eye. [Solution] Provided is a simulation system comprising: an acquisition unit that acquires a non-insertion image, which is an image, captured by a tomographic device, of an anterior ocular segment of a subject's eye into which a posterior chamber phakic intraocular lens has not been inserted; a generation unit that generates, on the basis of the non-insertion image and the size of a posterior chamber phakic intraocular lens to be inserted into the subject's eye, an insertion image, which is an image of the anterior ocular segment of the subject's eye into which the posterior chamber phakic intraocular lens has been inserted; an identification unit that identifies, on the basis of the insertion image, an optimal size, which is the optimal size of the posterior chamber phakic intraocular lens to be inserted into the subject's eye; and an output unit that outputs information relating to the optimal size.

1. The name of the design product: ultrasonic emulsification instrument for ophthalmology. 2. The use of the design product: used in ophthalmic operating room, the operation equipment for cataract lens core fragmentation, perfusion and suction and anterior segment vitrectomy and electrocoagulation. 3. The design points of the design product: in shape. 4. The picture or photo that can best show the design points: perspective view 1.

The disclosure provides a method of treating, ameliorating, and / or preventing retinal degenerations, such as but not limited to anterior segment ocular disorders and / or age-related macular degeneration (AMD), in a subject. In certain embodiments, the method comprises administering to the subject a therapeutically effective amount of a compound of the disclosure. In certain embodiments, the compound of the disclosure prevents and / or minimizes cellular assault, such as oxidative stress-related cellular assault, and / or promote cell viability.

This invention provides an ophthalmic measurement system based on a frequency-adjusting device, comprising an OCT light source, a reference arm, a sample arm module, an optical fiber coupler, and a detector. The sample arm module integrates an optical path switching scanning device, capable of reflecting the probe light to the posterior or anterior segment of the eye. By introducing a frequency-adjusting device to dynamically adjust the optical path, maintaining a constant optical path or phase change between the A and Scan, Doppler frequency shift is achieved, enhancing detection depth without sacrificing resolution. The system can rapidly switch imaging focal points to adapt to eyes with different vision and perform refractive compensation, acquiring high-resolution OCT images. Furthermore, the system can accurately measure key parameters such as corneal curvature, thickness, anterior chamber depth, and lens thickness, effectively improving diagnostic speed. This invention overcomes the limitations of existing technologies in detection depth, imaging speed, and accuracy while ensuring image quality.

The invention discloses an ophthalmology ultrasound RF signal enhancement method and device and a model training method and device, and relates to the technical field of ophthalmology ultrasound and the technical field of deep learning, and the method comprises the steps: obtaining to-be-enhanced ophthalmology ultrasound RF signal data of a target object, the to-be-enhanced RF signal data is obtained by performing ophthalmologic ultrasonic scanning on eyeballs of a target object through eyelids by adopting high-frequency pulse sound waves; rF signal data to be enhanced are input into a pre-trained signal enhancement model, blind deconvolution calculation is carried out on the RF signal data to be enhanced, obtained output serves as enhanced RF signal data, and the signal enhancement model is a deep learning model. By the adoption of the scheme, the comfort level of a patient during anterior segment ophthalmic ultrasonic examination is improved, and the examination efficiency is improved.

An ophthalmic apparatus of an aspect example includes an image acquiring unit, a corneal shape estimating processor, and a first image correcting processor. The image acquiring unit is configured to acquire an anterior segment image constructed based on data collected from an anterior segment of a subject's eye by optical coherence tomography (OCT) scanning. The anterior segment image includes a missing part corresponding to a part of a cornea. The corneal shape estimating processor is configured to estimate a shape of the missing part of a cornea image by analyzing the anterior segment image acquired by the image acquiring unit. The first image correcting processor is configured to correct distortion of the anterior segment image based at least on the shape of the missing part estimated by the corneal shape estimating processor.

An ophthalmic preparation for treating macular edema, optic neuritis and non-infectious endophthalmitis contains an active ingredient for treating eye diseases and an ophthalmic preparation carrier or auxiliary material. The active ingredient for treating eye diseases is a glucocorticoid medicine and / or a non-steroidal medicine. The ophthalmic preparation carrier or auxiliary material contains the following ingredients: a surfactant, an ionic polymer and a solvent, or the ophthalmic preparation carrier or auxiliary material contains the following ingredients: povidone with low polymerization degree, povidone with moderate polymerization degree and a solvent. The ophthalmic preparation can carry (wrap) the glucocorticoid and / or the non-steroidal medicines to penetrate through the anterior segment of eyes and be conveyed to the posterior segment of eyes to treat the macular edema, the optic neuritis and the non-infectious endophthalmitis in an eye drop administration mode, and the ophthalmic preparation has extremely excellent clinical use value and positive social significance.

The invention discloses a cornea blood vessel nebula area automatic identification and cutting parameter optimization system in a refractive operation, and relates to the technical field of ophthalmic refractive operations. The system comprises an anterior segment image acquisition module, an image processing module, a central processing module, an image display module, a data storage module and a parameter optimization module which are connected in sequence, the anterior segment image acquisition module acquires an anterior segment image of a user; the image processing module is used for processing the acquired anterior segment image of the user; the central processing module compares a cutting area range designed by the refractive surgery with the processed image; the image display module displays a comparison result; the data storage module stores the comparison result; and the parameter optimization module optimizes and adjusts the cutting parameters of the refractive surgery according to the comparison result. According to the method, corneal vessel nebula can be automatically identified, the position and range of the vessel nebula are compared with the cutting range, and corneal refractive surgery cutting area and incision position parameters are optimized.

An ultrasound-excited elastography device and detection method for measuring the mechanical properties of the cornea and retina are disclosed. The ultrasound excitation module uses three-dimensionally localizable focused ultrasound waves to excite elastic waves in the cornea or retina. Its transducer axis is angled to the OCT optical axis, and the sound wave path is deflected by an obliquely placed acoustic reflector. The OCT module dynamically captures the spatiotemporal displacement signals of the tissue induced by the elastic waves through a dual-scan mode, achieving high-resolution imaging of the anterior segment and fundus. The eye cup fitting module, combined with a biocompatible structure, adapts to the eye contour and coordinates the incident angle of the sound waves to optimize the acoustic-optical coupling efficiency. The data processing module derives the Young's modulus distribution of the tissue using an elastography algorithm. The detection method achieves high-precision quantitative analysis of the mechanical properties of the cornea and retina through non-invasive ultrasound-OCT co-excitation and signal acquisition, combined with a motion platform to compensate for eye movement deviations in real time. This invention provides a reliable tool for assisting in the diagnosis of ophthalmic diseases.

The invention provides an intelligent full-automatic diagnosis and analysis method and device for anterior segment diseases, electronic equipment and a storage medium, and the method comprises the steps: obtaining an eye image of a patient; inputting the eye image of the patient into a target detection grading model, identifying a focus area of the eye image of the patient based on the target detection grading model, and determining at least one predicted disease type and a severity level of the predicted disease type based on the focus area of the eye image of the patient; and generating an auxiliary diagnosis report based on the predicted disease type and the severity level of the predicted disease type. The method can assist a doctor in positioning a disease area, a focus type and a severity level, so that the diagnosis efficiency and accuracy are improved.

The invention discloses an ophthalmological diagnostic instrument, and relates to the technical field of medical equipment.The ophthalmological diagnostic instrument comprises a topographic map structure, a crack projection structure, an off-axis imaging structure, a dichroic optical element and a rotating mechanism, opaque circular rings and semitransparent circular rings which are alternately distributed are arranged on the Praxiso disc, the red light source is configured to perform backlight illumination on the semitransparent circular rings, and the first camera is a color sensitive image sensor, is aligned along the visual axis of the eye and is used for capturing a Praxiso pattern reflected by the surface of the cornea and a color image of the anterior segment of the eye; the fissure projection structure comprises a visual axis along the topographic map structure and projects a blue fissure light beam to the anterior segment, the off-axis imaging structure comprises a second camera, the second camera is obliquely arranged relative to the visual axis and is used for capturing an anterior segment cross section image irradiated by the blue fissure light beam, and the dichroic optical element is arranged along the visual axis.

1. The name of the design product: ophthalmic surgical equipment. 2. The use of the design product: the design product is used for the surgical system of anterior and posterior segment of eye surgery, and ophthalmic cataract phacoemulsification and vitrectomy surgery. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

This invention provides a method, terminal, and storage medium for extracting intraocular pressure (IOP) information from anterior segment images. First, an anterior segment image of the subject is acquired using a three-dimensional corneal tomography system. Then, anterior segment information is extracted from the image. Finally, the IOP of the subject is determined based on the anterior segment information and a pre-trained IOP prediction model. By using image recognition technology to extract features from the captured anterior segment image and then analyzing them using the trained IOP prediction model, IOP detection can be achieved without contact with the patient or damage to the eyeball, effectively ensuring the safety of the detection process.

1. The name of the design product: ultrasonic emulsification instrument for ophthalmology. 2. The use of the design product: surgical equipment for ophthalmic surgery, performing cataract lens core fragmentation, perfusion and suction, and anterior segment vitrectomy and electrocoagulation. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

To provide an ophthalmic device that can measure corneal shape without increasing the subject's discomfort due to glare. [Solution] An ophthalmic device for measuring the corneal shape of an eye under examination, comprising: a first projection optical system that projects a first pattern indicator onto the cornea of ​​the eye under examination using invisible light; a second projection optical system that projects a second pattern indicator onto the cornea of ​​the eye under examination using visible light; an anterior segment imaging optical system that receives reflected light from the anterior segment of the eye under examination; and a control unit, wherein the control unit analyzes and processes imaging data obtained by receiving the reflected light of the first pattern indicator projected onto the cornea of ​​the eye under examination by the first projection optical system with the anterior segment imaging optical system to determine whether or not corneal shape measurement of the eye under examination can be performed, and if it is determined that corneal shape measurement is possible, the second projection optical system projects a second pattern indicator onto the cornea of ​​the eye under examination, and analyzes and processes imaging data obtained by receiving the reflected light of the second pattern indicator with the anterior segment imaging optical system to measure the corneal shape.

This invention discloses a method and device for anterior segment Sham elastography. This invention combines micron-level spatial resolution, high cost-effectiveness, and clinical operability. It can obtain quantitative elastic distribution of anterior segment tissues such as the cornea in vivo and in situ, providing reliable biomechanical basis for ophthalmic diagnosis and treatment scenarios such as early screening of keratoconus, refractive surgery planning, and glaucoma risk assessment. Compared with the prior art, the system structure of this invention is simplified, the cost is significantly reduced, and it has higher resolution and achieves truly non-contact measurement.

The invention discloses a slit lamp microscopic imaging device integrated with a fundus observation function, and belongs to the technical field of ophthalmology detection, and the device comprises a moving base, a jaw bracket, a light source supporting arm, a microscope supporting arm, a slit illumination assembly, a fundus illumination assembly and a microscopic observation assembly; a central shading diaphragm is arranged on a newly added fundus lighting light path, a front collecting lens capable of movably moving in or out of the light path is arranged between the plane mirror and the microscopic observation assembly, and light combination of the crack lighting light path and the fundus lighting light path is achieved through a beam splitter prism. According to the invention, the central energy of the light beam irradiated to the cornea can be reduced, the fundus examination safety is improved, the interference of cornea reflection stray light is effectively avoided, the fundus imaging quality is improved, the integrated detection of the anterior segment and the fundus tissue is realized, and the efficiency and stability of ophthalmic clinical detection are improved.

The invention provides a hyperspectral imaging device for an anterior segment of an eye, and the device comprises an illumination light path which comprises a light source; an imaging light path; the first spectroscope is used for dividing light emitted by the imaging light path into reflected light and transmitted light; the image acquisition light path is used for receiving the reflected light and converting a light signal of the reflected light into an electric signal; the hyperspectral data acquisition light path is used for receiving the transmission light; the angle of the scanning reflecting mirror is adjustable; and the controller is configured to adjust the deflection angle of the scanning reflector based on the position of the to-be-detected area of the anterior segment contained in the image, so that light reflected by the to-be-detected area of the anterior segment can be projected into the hyperspectral data acquisition light path along the optical axis direction of the hyperspectral data acquisition light path. According to the device provided by the invention, more reference bases are provided for a doctor to classify and diagnose diseases, the influence of human eye shaking on spectral data is remarkably reduced, and the accuracy is improved.

A method for constructing a personalized human eye model. This includes the following steps: (1) simplifying the structural parameters of the human eye to establish a personalized three-dimensional full-eye geometric model; (2) determining the viscoelastic material parameters of the human cornea; (3) using fluid-structure interaction to simulate the actual boundary conditions of the human eye, analyzing the changes in the actual state of the human eye, selecting appropriate element types, discretizing the model into a finite number of aggregates, completing the construction of the finite element human eye model, and solving the model using finite elements; (4) simulating optical coherence elastography of the anterior segment tissues such as the cornea. Considering the individual differences in the geometric morphology and tissue material parameters of the human eye, based on clinical ophthalmological diagnostic data, a personalized full-eye model containing complete geometric morphological information of the human eye was established in finite element software using an elastography method, providing theoretical guidance and technical support for ocular tissue optical coherence elastography equipment.

An ophthalmic measurement system with an optical path compensation deflection mechanism includes an OCT light source, a reference arm, a sample arm module, an optical fiber coupler, a detector, and the optical path compensation deflection mechanism. The sample arm module contains an optical path switching scanning device that can reflect the probe light to the posterior or anterior segment of the eye. The optical path compensation deflection mechanism includes a rotation mechanism and an optical path compensation deflection component. This mechanism can dynamically adjust the optical path, maintaining a constant optical path or phase change between the A-scan and the posterior segment, simulating the Doppler frequency shift effect without increasing hardware costs. The system can avoid using loading frequency technology in the preview stage, reducing sampling requirements and lowering costs. A shallow probe depth is used during measurement for rapid alignment with the eye under test, improving accuracy. Rapid switching of scanning modes allows for accurate measurement of axial length, anterior chamber depth, and lens thickness. This invention provides a cost-effective, easy-to-operate, and accurate ophthalmic OCT imaging solution that meets clinical diagnostic needs.

The application discloses a kind of early warning method and device of children's eye disease and systemic genetic syndrome, it is related to ophthalmic examination equipment technical field.The method includes: collection ocular anterior segment image data set, utilize the multi-task segmentation model after training, obtain multiple congenital eye disease quantitative feature data, then based on the risk index calculator of pre-established index calculation is carried out, and the congenital eye disease risk index is obtained, classification processing is carried out, matches eye abnormal phenotype, and obtains systemic disease early warning report.The application can realize more than 10 kinds of congenital eye disease and rare but important lesion in one examination screening, and simultaneously establishes the intelligent early warning system of eye phenotype and systemic genetic syndrome.

A system, method, or device for imaging the anterior segment of an eye includes a contactless adapter / lens that may be attached to an existing ophthalmic imaging system to redirect the imaging system's light beam to traverse the pupil of the eye at a steep angle. In particular, the steep angle is determined to permit the ophthalmic imaging system to image zonules under the iris, and which would typically be blocked by the iris and not accessible for imaging.

This invention relates to the field of medical image analysis technology, specifically disclosing a method and system for anterior segment image analysis. The method includes: acquiring anterior segment images and extracting features to obtain shared features; inputting the shared features into coarse-grained and fine-grained branches respectively to obtain output features of the coarse-grained and fine-grained branches; performing asymmetric feature fusion with gradient stopping, and then passing the results through corresponding classifiers to obtain anatomical classification prediction results of the coarse-grained branch and disease classification prediction results of the fine-grained branch. This invention jointly models coarse-grained anatomical features and fine-grained disease representations, which can significantly improve recognition accuracy and model generalization ability, realize automated analysis of ophthalmic images, and promote the widespread application of intelligent medical technology in clinical practice.

The invention provides an anterior segment index measurement method and system, computer equipment and a storage medium, and belongs to the field of medical image processing and computer vision. Comprising the following steps: acquiring an eyeball OCT image of a target object; extracting multi-scale texture features of the eyeball OCT image, and converting the texture features into structural features; converting the structural features into spatial domain enhancement features and frequency domain enhancement features in the spatial dimension and the frequency dimension respectively; fusing the spatial domain enhancement feature and the frequency domain enhancement feature to obtain a fused full-dimensional feature; generating eye tissue contour features according to the full-dimensional features; and measuring and calculating based on the eye tissue contour features to obtain the anterior segment biological index. According to the method, the segmentation precision of the tissue boundary in the complex eyeball OCT image can be effectively improved, and automatic and high-precision calculation of multi-dimensional indexes is realized.

The application relates to the field of image processing and discloses an OCT conjugate mirror image removing method and device based on deep learning, which comprises the following steps: constructing a complex conjugate image of spectral data, constructing a true anterior eye segment image of the spectral data, performing image preprocessing on the complex conjugate image and the true anterior eye segment image; analyzing a pseudo-anterior eye segment image corresponding to the preprocessed conjugate image, calculating an absolute value loss between the pseudo-anterior eye segment image and the preprocessed anterior eye segment image; discriminating the falsity between the pseudo-anterior eye segment image and the preprocessed conjugate image, discriminating the authenticity between the preprocessed conjugate image and the preprocessed anterior eye segment image, calculating a generative network loss of a generative network; performing model training on a pre-trained neural network model to obtain a trained neural network model; performing model verification on the trained neural network model to obtain a verified neural network model, calculating a peak signal-to-noise ratio of the verified neural network model, and selecting a final neural network model. The application can reduce the difficulty of removing the OCT conjugate mirror image.

The present invention relates to an oil-in-water microemulsion that has shown to be a suitable drug depot system for the treatment of disorders of the anterior segment of the eye, wherein said disease is selected from the group consisting of corneal neovascularization disease (NV), ocular melanoma, Gelatinous drop-like corneal dystrophy (GDLD), Secondary corneal amyloidosis—GDLD type, Graves ophthalmopathy, Stevens-Johnson syndrome (SJS), Mooren's ulcer, and Corneal graft rejection and more particularly of neovascularization disease (NV). The microemulsion according to the invention is indeed capable of effectively delivering and maintaining on the anterior segment of the eye high concentrations of active ingredients after administration.

The invention discloses ultrasonic excitation elastic imaging equipment for measuring mechanical properties of cornea and retina and a detection method. Wherein the ultrasonic excitation module excites cornea or retina to generate elastic waves through focused ultrasonic waves capable of being positioned in a three-dimensional mode, the axis of a transducer of the ultrasonic excitation module and the optical axis of the OCT are arranged in an angle mode, and a sound wave path is deflected by means of an inclined acoustic reflector plate; the OCT module dynamically captures tissue space-time displacement signals caused by elastic waves in a double-scanning mode, and high-resolution imaging of the anterior segment and the fundus is achieved; the eye cup adaptation module is combined with a biocompatibility structure to adapt to the eye contour, cooperatively regulates and controls the incidence angle of sound waves and optimizes the acousto-optic coupling efficiency; and the data processing module deduces tissue Young modulus distribution through an elastography algorithm. According to the detection method, non-invasive ultrasonic-OCT collaborative excitation and signal acquisition are combined with a motion platform to compensate eye movement deviation in real time, and cornea and retina are realized. And carrying out high-precision quantitative analysis on mechanical properties. The invention provides a reliable tool for assisting ophthalmic disease diagnosis.