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High-barrier infusion film and preparation method thereof

An infusion film and high-barrier technology, applied in the field of high-barrier infusion film and its preparation, can solve the problems of increased process complexity, human hazards, poor moisture and gas barrier performance, etc., to avoid the decline of gas barrier performance and good heat resistance performance, high barrier effect

Pending Publication Date: 2022-03-22
江苏博生医用新材料股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a traditional packaging container, glass infusion bottles have the advantages of low price, chemical stability, and transparency, but their quality and volume are large, and there are disadvantages such as inconvenient transportation, complicated production process, and fragility, which gradually cannot meet people's needs.
Plastic bottles overcome the shortcomings of glass bottles to a certain extent, but their transparency and high temperature resistance are poor, so they are not suitable for the use of amino acid pharmaceuticals
Moreover, glass bottles and plastic bottles need to form an air circuit when they are in use, and the external air enters the bottle to form internal pressure to make the medicine drip out, which will increase the secondary pollution in the infusion process
In order to solve this problem, PVC soft bags came into being, but PVC soft bags contain polyvinyl chloride monomer, which is not conducive to human health, and PVC soft bags contain a plasticizer, dihexyl phthalate (DEHP). ), this substance is easy to enter the human body by dissolving and infiltrating into the medicine, and will have harmful effects on the human body
[0003] The non-PVC soft bag is a multi-layer co-extrusion infusion bag, which has good mechanical properties and stable physical and chemical properties, is easy to transport, and is widely favored by the market, but the moisture resistance of the multi-layer co-extrusion infusion bags currently used in China The gas barrier performance is poor, and a high-barrier outer bag is generally used to place it outside the infusion bag, which increases the complexity of the process

Method used

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  • High-barrier infusion film and preparation method thereof
  • High-barrier infusion film and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0049] The high-barrier infusion membrane provided in this embodiment includes a moisture barrier layer, a gas barrier layer, a reinforcement layer and an outer layer that are tightly fitted in sequence from the inside to the outside, and an adhesive layer is provided between adjacent two layers;

[0050] Among them, the composition of the moisture barrier layer is a mixture of linear low density polyethylene, cycloolefin, maleic anhydride grafted polyethylene and nano-zinc oxide with a mass ratio of 1:2:1.5:0.5; the composition of the gas barrier layer is a mass ratio of A mixture of polyethylene terephthalate and ethylene-vinyl alcohol copolymer of 1.2:2.5; the composition of the reinforcing layer is adipic acid-terephthalic acid-butylene glycol with a mass ratio of 2:0.8:1.2 A mixture of ester copolymer, polylactic acid and glycidyl methacrylate; the composition of the outer layer is polypropylene, polyester elastomer and styrene-ethylene-butadiene-styrene in a mass ratio of...

Embodiment 2

[0053] The high-barrier infusion membrane provided in this embodiment includes a moisture barrier layer, a gas barrier layer, a reinforcement layer and an outer layer that are tightly fitted in sequence from the inside to the outside, and an adhesive layer is provided between adjacent two layers;

[0054] Among them, the composition of the moisture barrier layer is a mixture of linear low density polyethylene, cycloolefin, maleic anhydride grafted polyethylene and nano-zinc oxide with a mass ratio of 1.2:2:1.5:0.6; the composition of the gas barrier layer is a mass ratio of A mixture of polyethylene terephthalate and ethylene-vinyl alcohol copolymer of 0.8:2.5; the composition of the reinforcement layer is adipic acid-terephthalic acid-butylene glycol in a mass ratio of 2:0.8:1.2 A mixture of ester copolymer, polylactic acid and glycidyl methacrylate; the composition of the outer layer is a mixture of polypropylene, polyester elastomer and styrenic block copolymer in a mass rat...

Embodiment 3

[0057] The high-barrier infusion membrane provided in this embodiment includes a moisture barrier layer, a gas barrier layer, a reinforcement layer and an outer layer that are tightly fitted in sequence from the inside to the outside, and an adhesive layer is provided between adjacent two layers;

[0058] Among them, the composition of the moisture barrier layer is a mixture of linear low density polyethylene, cycloolefin, maleic anhydride grafted polyethylene and nano-zinc oxide with a mass ratio of 0.8:2:1.5:0.5; the composition of the gas barrier layer is a mass ratio of A mixture of polyethylene terephthalate and ethylene-vinyl alcohol copolymer of 1.2:2.5; the composition of the reinforcing layer is adipic acid-terephthalic acid-butylene glycol with a mass ratio of 2:0.8:1.2 A mixture of ester copolymer, polylactic acid and glycidyl methacrylate; the composition of the outer layer is a mixture of polypropylene, polyester elastomer and styrenic block copolymer in a mass rat...

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Abstract

The invention relates to the field of infusion materials, in particular to a high-barrier infusion film and a preparation method thereof.The high-barrier infusion film comprises a moisture barrier layer, an air barrier layer, a reinforcing layer and an outer layer which are tightly attached in sequence from inside to outside, and a bonding layer is arranged between every two adjacent layers; through the design of the laminated multi-layer structure and the components of each layer, the infusion film has excellent gas and water vapor barrier property and antibacterial ability, also has good toughness and scratch resistance, and meets the requirements on infusion film materials.

Description

technical field [0001] The invention relates to the field of transfusion materials, in particular to a high-barrier transfusion membrane and a preparation method thereof. Background technique [0002] At present, the more common infusion packaging containers on the market in my country include infusion bottles, plastic bottles, polyvinyl chloride soft bags (PVC for short) and non-PVC soft bags. As a traditional packaging container, glass infusion bottles have the advantages of low price, chemical stability, and transparency, but their quality and volume are large, and they have disadvantages such as inconvenient transportation, complicated production process, and fragility, which gradually cannot meet people's needs. Plastic bottles overcome the shortcomings of glass bottles to a certain extent, but their transparency and high temperature resistance are poor, so they are not suitable for the use of amino acid pharmaceuticals. Moreover, glass bottles and plastic bottles need...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B32B27/08
CPCB32B27/08B32B27/32B32B27/325B32B27/30B32B27/36B32B27/306B32B27/302B32B27/308B32B27/18B32B7/12B29D7/01C08J5/18C09J123/0869C09J167/06A61J1/1406B32B2535/00B32B2307/7246B32B2307/7265B32B2307/7145B32B2307/558C08J2351/06C08J2423/08C08J2323/08C08J2467/02C08J2367/02C08J2467/04C08J2323/12C08J2467/00C08J2453/02C08L23/0853C08L67/06C08L23/0869Y02W90/10
Inventor 田仁和张志辉王亚楠姜永倪小琴王永亮刘如俊
Owner 江苏博生医用新材料股份有限公司