Silk protein-based sweat-wet-resistant flexible pressure sensor and method and application thereof

Abstract

The invention discloses a silk protein-based sweat-wet-resistant flexible pressure sensor, and a method and application of the silk protein-based sweat-wet-resistant flexible pressure sensor. The electrode comprises two electrode layers and an ionic dielectric layer sandwiched between the electrode layers, the electrode layers are fibroin films with micro-bulge structures and gold patterns, and the ionic dielectric layer is a fibroin/ionic liquid fiber felt; due to double sensitization of the double electric layer effect of the ion-electron interface and the micro-bulge structure, the blood pressure sensor has very high sensitivity, and the accuracy of blood pressure monitoring is ensured; due to the high air permeability of the silk protein material and the fiber structure, the sensor has good air permeability and sweat wet resistance, and the blood pressure can be accurately measured under the condition that the sensor is worn for a long time or the skin sweats. The pressure sensor is small in size and light in weight, has high air permeability, high sensitivity and high biocompatibility, can improve the accuracy and comfort of long-term continuous monitoring of blood pressure, and has wide application prospects.

Description

technical field [0001] The invention belongs to a flexible pressure sensor in the technical field of materials, and particularly relates to a fibroin-based anti-sweat flexible pressure sensor, a preparation method and an application thereof. Background technique [0002] Non-invasive long-term continuous blood pressure monitoring plays a vital role in the early diagnosis and prevention of cardiovascular disease. Although the traditional cuff-type sphygmomanometer can monitor human blood pressure non-invasively, the cuff is bulky and inflexible, poor in wearability and comfort, and the measurement process is intermittent. [0003] At present, the cuffless continuous blood pressure monitoring mainly adopts the pulse transit time (PTT) method, and the blood pressure measurement is realized by the combination of the pulse wave and the ECG signal. The key is to get an accurate and true pulse signal. Most wearable devices use photoplethysmography (PPG) sensors composed of LEDs a...

AI Technical Summary

Problems solved by technology

However, these sensors are usually made of airtight flexible rubber, such as PDMS, Ecoflex, PVDF, etc. After long-term wearing, the sweat between the sensor and the skin will greatly affect the accuracy of the pulse signal, even make the device invalid, and cause skin discomfort or allergies

Although some pressure sensors with porous structure or fiber structure have been researched and proposed to improve air permeability, they are difficult to have high sensitivity at the same time, and cannot accurately sense the weak skin deformation caused by the pulse, which affects the accuracy and fidelity of the signal.

In addition, the materials used to construct flexible pressure sensors, such as metal nanomaterials, carbon-based nanomaterials, etc., usually have low biocompatibility, which limits their practical applications in the wearable field.

[0005] In the prior art, there is a lack of sweat-resistant flexible pressure sensors with high air permeability, high sensitivity, and high biocompatibility

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