Medicine for treating coronary disease and stenocardia and its preparation method

A technique for angina pectoris and coronary heart disease, which is applied in the field of medicines for treating coronary heart disease and angina pectoris and their preparation, can solve the problems of inability to completely solve coronary stenosis, large toxic and side effects of western medicine, and many adverse reactions, and achieves significant curative effect and toxic and side effects. Low, reduced myocardial oxygen consumption and blood viscosity

Active Publication Date: 2006-11-01
XIAN CHIHO PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In summary, the role of drug therapy is to relieve or reduce the attack of angina, but it cannot completely solve the problem of coronary artery stenosis
The acute attack stage of the disease can be basically cont

Method used

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  • Medicine for treating coronary disease and stenocardia and its preparation method

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[0039] The preparation methods of Pueraria lobata total flavonoids, hawthorn extract, and Gynostemma total glycosides are:

[0040] 1. Pueraria lobata total flavonoids

[0041] This product is an ethanol extract (total flavonoids) extracted from the legume wild root Pueraria Iobata (Willd) Ohwi. It contains puerarin (C 21 H 20 O 9 ) Shall not be less than 15.0%.

[0042] [Preparation method] Take the crude kudzu powder, the percolation method under the item of Zhaoliu extract and extract (Appendix IO of the Chinese Pharmacopoeia 1995 edition), use ethanol as the solvent, immerse for 2 days and then percolate, collect the effluent, reduce Press to recover the ethanol and concentrate it into a thick paste, spray powder and dry it, and get it.

[0043] 2. Hawthorn extract

[0044] This product is a 70% ethanol extract of Crataegus pinnatifida Bge var.major N.E.Br. Crataegus pinnatifida Bgede. Dry for 6 hours at 60℃, containing rutin (C 27 H 30 O 16 ) Shall not be less than 2.0%.

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Abstract

A medicine for treating coronary heart disease and angina pectoris and a preparation method thereof. Soybean oil 5-100; beeswax 0.1-3; hydrogenated palm oil 0.4-10; soybean lecithin 0.2-5; methyl silicone oil 0.01-0.5; gelatin 8-150; glycerin 3-80; distilled water 8-150; Esters 0.01-0.8, the preparation method is to use appropriate amount of distilled water, gelatin, glycerin, and ethyl p-hydroxybenzoate to prepare glue; add quantitative beeswax and hydrogenated palm oil to soybean oil, and heat to make the above two substances in soybean oil Completely dissolve, cool, add soybean lecithin, stir well to make it uniform; then add gypenosides, hawthorn extract, and kudzu root flavonoids powder that have been passed through a 60-mesh sieve one by one, stir well to make it evenly mixed, and pass through a colloid mill for 2 times , add methyl silicone oil, let it stand, and vacuumize until the air bubbles in the liquid are basically removed, and set aside; use the gelatinized pellets that have been melted, each containing 580mg, and the thickness of the rubber is about 0.85-0.95mm, and the pellets are made by pressing.

Description

technical field [0001] The invention relates to a medicine for treating coronary heart disease and angina pectoris and a preparation method thereof. Background technique [0002] Coronary heart disease and angina pectoris refer to clinical syndromes caused by coronary insufficiency, acute and temporary myocardial ischemia and hypoxia. The principle of treatment of coronary heart disease and angina pectoris is to improve the blood supply of the coronary arteries and reduce the oxygen consumption of the myocardium, while treating atherosclerosis. Therapeutic drugs are divided into three categories: the first category is nitrate preparations, the main function is to expand the coronary arteries, reduce resistance, and increase blood flow in the coronary circulation. Ventricular volume, cardiac internal pressure, cardiac output and blood pressure, reduce cardiac preload and myocardial oxygen demand, thereby relieving angina pectoris, commonly used preparations are nitroglycerin...

Claims

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Application Information

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IPC IPC(8): A61K36/734A61K36/48A61K36/424A61K9/20A61P9/10
Inventor 任建国郭建文
Owner XIAN CHIHO PHARMA
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