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Novel monascin oral liquid and method for producing the same

A red yeast oral liquid and a technology for red yeast rice, which are applied in the field of new red yeast oral liquid, can solve the problems of difficult separation and extraction of bioactive substances, difficult expansion of production scale, large production labor, etc., and achieve a novel product concept and a marketable product. Potential, Feature Unique Effects

Inactive Publication Date: 2004-11-10
西安利君制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Red yeast rice at home and abroad is mostly produced by solid-state fermentation, which has many disadvantages, such as long production cycle, large production labor, difficult expansion of production scale, difficult separation and extraction of biological active substances, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] (1) Preparation of ganoderma lucidum fermented liquid:

[0027] ① Preparation of seed medium: corn flour 3%, glucose 3%, magnesium sulfate 0.2%, yeast powder 0.5%, potassium dihydrogen phosphate 0.2%. Sterilize at 121°C.

[0028] ② Inoculate Ganoderma lucidum strains and culture at 27°C for 3 days.

[0029] ③ Preparation of fermenter medium: 4% sucrose, 2% glucose, 0.1% potassium dihydrogen phosphate, 0.1% magnesium sulfate, 0.4% yeast powder. Sterilize at 121°C.

[0030] ④ Put the seeds into a fermenter and culture them at 27° C. for 4 days to obtain a ganoderma lucidum fermentation liquid.

[0031] (2) Preparation of Monascus fermented liquid

[0032] ① Preparation of seed medium: rice flour 8%, magnesium sulfate heptahydrate 0.15%, sodium nitrate 0.3%, potassium dihydrogen phosphate 0.2%. Sterilize at 121°C.

[0033] ② Inoculate Monascus strains and culture at 26°C for 3 days.

[0034] ③ Preparation of fermenter culture medium: 80% (volume ratio) of Ganoderma ...

Embodiment 2

[0043] (1) Preparation of ganoderma lucidum fermented liquid:

[0044] ① Preparation of seed medium: 4% corn flour, 2% glucose, 0.25% magnesium sulfate, 0.35% yeast powder, and 0.2% potassium dihydrogen phosphate. Sterilize at 121°C.

[0045] ② Inoculate Ganoderma lucidum strains and culture at 27°C for 3 days.

[0046] ③ Prepare fermenter medium: 3% sucrose, 2% glucose, 0.2% potassium dihydrogen phosphate, 0.1% magnesium sulfate, and 0.4% yeast powder. Sterilize at 121°C.

[0047] ④ Put the seeds into a fermenter and culture them at 27° C. for 4 days to obtain a ganoderma lucidum fermentation liquid.

[0048] (2) Preparation of Monascus fermented liquid

[0049] ① Preparation of seed medium: rice flour 6%, magnesium sulfate heptahydrate 0.05%, sodium nitrate 0.3%, potassium dihydrogen phosphate 0.2%. Sterilize at 121°C.

[0050] ② Inoculate Monascus strains and culture at 26°C for 3 days.

[0051] ③ Preparation of fermenter culture medium: 80% (volume ratio) of Ganoder...

Embodiment 3

[0057] (1) Prepare Ganoderma lucidum extract:

[0058] Ganoderma lucidum fruiting body 100g, crushed into the size of mung beans, put into the pot, add 1 liter of water at 80°C, soak for 1 hour, filter, it is the first extraction liquid. Add 1 liter of water at 80°C to the residue, soak for 3 hours, Filtration is the second extract. The two extracts are combined to obtain the ganoderma lucidum extract.

[0059] (2) Preparation of Monascus fermented liquid

[0060] ① Preparation of seed medium: rice flour 6%, magnesium sulfate heptahydrate 0.1%, sodium nitrate 0.25%, potassium dihydrogen phosphate 0.15%. Sterilize at 121°C.

[0061] ② Inoculate Monascus strains and culture at 26°C for 3 days.

[0062] ③ Preparation of fermenter medium: 0.3% sodium nitrate, 0.2% potassium dihydrogen phosphate, 0.25% magnesium phosphate heptahydrate, 80% (volume ratio) of Ganoderma lucidum extract. Sterilize at 121°C.

[0063] ④ Put the seeds into a fermenter and culture them at 27°C for 8 day...

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PUM

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Abstract

The invention discloses a novel red yeast oral liquid and method of production by using lucid ganoderma powder, lucid ganoderma extract and the secondary liquor of lucid ganoderma fermentation liquor through submerged cultuse, wherein the compositions are used as the main culture medium raw material in red yeast fermentation. The production method comprises red yeast liquid state fermentation, filtering the filtrate, adding in findings, split charging and sterilizing. The invention integrates the functions of reducing blood fat by the red yeast with liver protection by the lucid ganoderma.

Description

technical field [0001] The invention relates to a health care product, in particular to a new type of red yeast oral liquid refined by submerging red yeast powder, ganoderma lucidum extract or ganoderma lucidum fermentation liquid by modern biotechnology and a production method thereof. Background technique [0002] Red yeast rice has been used in my country for thousands of years. "Compendium of Materia Medica" records that red yeast rice has the function of "digesting food and promoting blood circulation, invigorating the spleen and drying the stomach", and can effectively regulate blood lipids. Modern studies have found that Monascus has many medicinal effects: regulating blood lipids; lowering blood sugar; antibacterial; anti-cancer; enhancing immunity; anti-inflammation and anti-oxidation; lowering blood pressure; reducing Alzheimer's disease, etc. The prevalence of hyperlipidemia in my country is as high as 7% or more, and it shows a trend of increasing year by year. ...

Claims

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Application Information

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IPC IPC(8): A23L2/38A23L3/3571
Inventor 赵振伟陈立王一心任建鸽纪维
Owner 西安利君制药股份有限公司