Intelligent molecular blotting affinity membrane for chiral resolution and its preparation method

Abstract

The present invention is chiral resolving affinity membrane for resolving, concentrating and separating chiral molecules and its preparation process. The present invention prepares temperature sensitive intelligent chiral resolving affinity membrane with porous inorganic or organic membrane as base membrane, and through heating polymerization or UV initiated polymerization of acrylate, acrylic acid, acrylamine, diacrylamine, isopropyl acrylamine, initiator and template molecule solution inside the pores and on the surface of the base membrane, and subsequent washing off the template molecule via altering the temperature. The preparation process includes the steps of: base membrane treatment, compounding monomer solution, polymerization and eliminating template. The intelligent chiral resolving affinity membrane has simple separation process, high chiral resolving capacity, high treating amount and no selectivity.

Description

1. Technical field

[0001] The invention belongs to the field of membrane separation technology for splitting chiral molecules, and in particular relates to the preparation of an intelligent molecule imprinted chiral splitting affinity membrane. 2. Background technology

[0002] Separation membrane is a high-efficiency and energy-saving separation material with broad application prospects. Membrane chiral separation is a new research hotspot that has been vigorously developed at home and abroad in recent years. Membrane-based chiral separation technology has both resolution and large-scale processing capabilities, and will play an important role in the separation of chiral molecules such as medicine, spices, biochemical reagents, and food additives.

[0003] Membrane separation Membrane technology to split chiral molecules mainly includes liquid membrane method, solid membrane method and membrane reactor method. Due to the disadvantages of poor stability of chiral liquid me...