Method of predicting serious complication risk degree after gastric cancer operation

A prediction method and complication technology, applied in surgery, diagnostic recording/measurement, sensors, etc., can solve problems such as poor practicability and operability, inability to verify and evaluate models, and inability to balance multiple confounding factors

Inactive Publication Date: 2007-06-06
NANJING UNIV
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Problems solved by technology

[0003] In the research field of risk factor determination and risk prediction of severe complications after gastric cancer surgery, there are still many shortcomings in the current research at home and abroad: (1) Some researchers collected few pathogenic factors and participated in fewer cases, which did not meet the One of the core requirements of modern evidence-based medicine, that is, clinical evidence should come from multi-center, large-sample randomized controlled clinical trials (RCT), systematic review (systematic review) and meta-analysis (meta-analysis); (2) some The researchers used a univariate analysis method, but the relationship between severe complications after gastric cancer surgery and many pathogenic factors is very complicated, and the univariate analysis cannot balance the effects of multiple confounding factors in the complex relationship, nor can it form a predictive model; (3) Some researchers use multiple linear regressi

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  • Method of predicting serious complication risk degree after gastric cancer operation

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Embodiment 1

[0020] Embodiment 1: A method for predicting the risk of serious complications after gastric cancer surgery, the method steps are as follows:

[0021] 1. Establishment of gastric cancer information database:

[0022] 1.1 Sources of clinical data:

[0023] The subjects of the study were 1542 patients who underwent gastric cancer surgery in Jiangsu Provincial People's Hospital, Drum Tower Hospital of Nanjing University, and General Hospital of Nanjing Military Region from June 2002 to June 2006. A retrospective case-control study was adopted. The case group consisted of patients with severe complications after surgery, and the control group consisted of gastric cancer surgery patients without serious complications who were hospitalized at the same time.

[0024] 1.2 Survey content All clinical data and information are subject to the original medical records, using uniform variable indicators, and all are input into the gastric cancer information database established with the SP...

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Abstract

The present invention is objective, quantitative and precise method of predicting serious complication risk degree after gastric cancer operation. The method includes the following steps: 1. screening out factors affecting the serious complication after gastric cancer operation through overall single factor analysis; 2. determining the prognostic determining factor through two-value multiple non-conditional logic regression analysis; 3. determining the optimal prediction value dividing value through the work characteristic analysis on the testee; and 4. establishing the predicting model with main risk factor as the independent variable and judging the serious complication risk degree after gastric cancer operation by means of the prediction probability. The present invention is one objective and quantitative intelligent risk evaluation system.

Description

1. Technical field [0001] The invention relates to a prediction method used in medicine, in particular to a method for predicting the risk of severe postoperative complications through the preoperative information, operation information, and tumor pathological information of gastric cancer patients. 2. Background technology [0002] In my country, gastric cancer is one of the most common malignant tumors, and its morbidity and mortality rank among the forefront of various malignant tumors. The main treatment methods for gastric cancer are surgery and adjuvant chemotherapy. Radical gastric cancer surgery is currently the only treatment that can achieve the purpose of cure. The standard radical surgery for gastric cancer includes gastrectomy, lymph node dissection, and reconstruction of the digestive tract. The surgical trauma is large and the operation is complicated. Since most gastric cancer patients in my country are elderly, they often have chronic co-morbidities, and mos...

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Application Information

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IPC IPC(8): A61B10/00A61B19/00G06F17/00G06Q50/00A61B5/00G06F19/00
Inventor 张坚郑晓兵张伟陶鹏德朱维铭黎介寿
Owner NANJING UNIV
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