Nonaqueous pressure-sensitive adhesive for medicinal tape preparation for percutaneous absorption, medicinal tape preparation for percutaneous absorption, and process for producing the same
a technology of pressure-sensitive adhesive and tape preparation, which is applied in the field of non-aqueous pressure-sensitive adhesive for can solve the problems of not finding a patent document or non-patent document, the pressure-sensitive adhesive layer lacks cohesive strength, and cannot be used in a tape preparation for percutaneous absorption, etc., to achieve excellent adhesive and cohesive strength, not irritated, and high safety with low skin irritation
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Benefits of technology
Problems solved by technology
Method used
Image
Examples
example 1
Production of Nonaqueous Pressure-Sensitive Adhesive 1
[0046]After charging 157.5 g of 2-ethylhexyl acrylate (hereinafter abbreviated as 2EHA), 35 g of 2-acetoacetoxyethyl methacrylate (hereinafter abbreviated as AAEM), 80.5 g of diacetoneacrylamide (hereinafter abbreviated as DAAM) and 76 g of methyl methacrylate (hereinafter abbreviated as MMA) in a 2-liter four-necked flask equipped with a Dimroth condenser, thermometer, nitrogen gas blow-in tube and stirrer, 525 g of ethyl acetate was added as a solvent and the mixture was dissolved to uniformity. The temperature was raised to 75° C. while blowing in nitrogen gas at flow rate of 100 ml / min. After holding at 75° C. for 30 minutes, a solution of 0.21 g of benzoyl peroxide as an initiator in 5 g of ethyl acetate was added, and the external temperature was set to 85° C. Subsequently, 300 g of toluene was loaded in portions of 100 g at a time at 3, 5 and 7 hours after adding the initiator. During the polymerization, nitrogen gas was c...
example 2
Production of Nonaqueous Pressure-Sensitive Adhesive 2
[0049]A monomer solution was prepared by uniformly pre-dissolving 78.8 g of 2EHA, 78.8 g of n-butyl acrylate (hereinafter abbreviated as BA), 105 g of AAEM, 87.5 g of MMA and 1.05 g of diethyleneglycol dimethacrylate (hereinafter abbreviated as DEGMA). After adding 100 g of the monomer solution in a 2-liter four-necked flask equipped with a Dimroth condenser, thermometer, nitrogen gas blow-in tube and stirrer, 350 g of ethyl acetate was added as a solvent. The temperature was raised to 75° C. while blowing in nitrogen gas at flow rate of 100 ml / min, and after holding at 75° C. for 30 minutes, a solution of 0.35 g of benzoyl peroxide as an initiator in 5 g of ethyl acetate was added, and the external temperature was set to 85° C. Upon confirming reflux of the solvent, the remaining monomer solution was loaded continuously for 3 hours. Next, one hour after the initial continuous loading of the monomer solution, 500 g of ethyl aceta...
example 11
Production of Tape Preparation for Percutaneous Absorption 11
[0082]A 36.2 g portion of pressure-sensitive adhesive 7, and then 1.5 g of ketoprofen, were placed in a screw-cap bottle and stirred for more than an hour in the bottle. A coating tester (LTE-S, Wener Mathis AG) was used for coating and drying of the solution onto a support (polyester film) to a dried coating weight of 140 mg / 10 cm2, and then a liner (silicon-treated polyester film) was used to cover it with the silicon side contacting the pressure-sensitive to obtain tape preparation for percutaneous absorption 11. The ketoprofen content of the obtained preparation was 10 w / w %.
PUM
Property | Measurement | Unit |
---|---|---|
Tg | aaaaa | aaaaa |
Tg | aaaaa | aaaaa |
temperature | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com