Lozenge for treating sore throat, hoarseness and associated dry cough, and inflammatory diseases of the oral and pharyngeal cavity

a technology of oral and pharyngeal cavity and lozenge, which is applied in the direction of biocide, plant/algae/fungi/lichens, drug compositions, etc., can solve the problems of mucosal irritation, normal mucosal function, sore throat and dry cough, and pulmonary infections, etc., and achieves the effect of largely absent side effects and well tolerated

Inactive Publication Date: 2014-10-02
BOEHRINGER INGELHEIM INT GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0019]The use of the combination according to the invention based on at least one astringent active substance and at least one mucilagino...

Problems solved by technology

Cold, dry or overheated room air as well as alcohol or nicotine adversely affect the normal function of the mucosa and may lead to mucosal irritation, hoarseness, sore throat and dry cough.
Under these circumstances, bacterial colonisation is promoted and pulmonary infections may result.
These frequently involve pain symptoms that are unpleasant for the patient and cause difficulty in swallowing.
Inflammations of the oral cavity e.g., gingivitis, stomatitis or oral mucosal lesions have symptoms that are unpleasant for the patient affected.
A...

Method used

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Examples

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Embodiment Construction

1. Production Examples

[0070]Production of pharmaceutical preparations according to the invention in the form of lozenges based on an astringent active substance in conjunction with different mucilaginous drugs.

[0071]Various compositions are produced in the form of lozenges based on powder compression or based on hard caramels. For the compressed lozenges, sugar substitutes, particularly isomalt, sorbitol or polydextrose may preferably be used, for the hard sweet base fructose and / or glucose syrup may be used, as sugar-free alternative sugar substitutes, particularly sugar alcohols, preferably maltitol or isomaltitol, may be used. Variable amounts of sweeteners (e.g. aspartame, acesulfame, cyclamate, saccharin or xylitol) may be added. Other excipients and active substances are incorporated in the matrix and the lozenges are produced by the production method known per se.

[0072]In the case of the compressed powder mixtures, the excipients are weighed in accordance with the recipe and ...

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Abstract

The present invention relates to a pharmaceutical formulation containing a combination of (a) at least one astringent active substance and (b) at least one mucilaginous drug and the use thereof for the prevention or treatment of inflammatory diseases of the oropharyngeal region and for the treatment of painful irritations of the mucosa in the oropharyngeal region and associated irritable cough.

Description

[0001]The present invention relates to a pharmaceutical formulation containing a combination of (a) at least one astringent active substance and (b) at least one mucilaginous drug and the use thereof for the prevention or treatment of inflammatory diseases of the oropharyngeal cavity and for treating painful irritations of the mucosa in the oropharyngeal region and irritable cough associated therewith.BACKGROUND TO THE INVENTION[0002]The present invention relates to a pharmaceutical composition in the form of a formulation suitable for sucking, the composition containing a combination of at least one astringent active substance with at least one second mucilaginous drug or an extract thereof, for the treatment of, in particular, irritations and inflammatory diseases of the oropharyngeal cavity, dry mouth and cough.[0003]The oral mucosa serves particularly to protect the underlying tissue and acts as a natural barrier against mechanical injuries (lesions) and against the penetration ...

Claims

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Application Information

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IPC IPC(8): A61K33/06A61K31/351A61K36/10A61K9/00A61K45/06
CPCA61K9/0056A61K36/10A61K45/06A61K31/351A61K33/06A61K36/28A61K36/68A61K36/185A61K36/09A61K31/7034A61P1/00A61P1/04A61P11/04A61P11/14A61P29/00A61K2300/00A61K36/062
Inventor BONI, JULIAPLOHMANN, BERNDSAUERLAND, SANDRA
Owner BOEHRINGER INGELHEIM INT GMBH
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