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Pharmaceutical or nutraceutical composition

a technology of nutraceuticals and pharmaceuticals, applied in the direction of peptide/protein ingredients, immunological disorders, metabolism disorders, etc., can solve the problems of many organic substances not stable in an acidic environment, heart and cerebrovascular disease, hyperactivity and insomnia,

Inactive Publication Date: 2015-06-18
GOLINI JEFFREY M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The alkalized compositions effectively buffer stomach acidity, prevent acidosis, increase physical strength and endurance, and treat a range of diseases by reducing the acidic load in the body, as demonstrated by improved muscle gain, endurance, and overall health benefits.

Problems solved by technology

The body dilutes the acids by retaining water, but this action, combined with arteriosclerosis, creates hypertension, which can lead to heart and cerebrovascular disease.
Salt-induced chloride acidosis has been found to cause irritability, hyperactivity and insomnia.
Many organic substances are not stable in an acidic environment and may convert into dangerous by-products.
In addition, the ingestion of acidic foods and acid-generating foods may cause the body to slip into metabolic acidosis.
The body has a variety of ways to compensate for mild acidosis, but prolong acid ingestion can result in weakness, headache, heavy or rapid breathing.
Severe acidosis can lead to acidemia, which is a build-up of acids in the blood, resulting in a coma or death.
Even mild acidosis can hinders athletic performance along with every day human life.
Lactic acid is a metabolic acid that is known to hinder athletic performance.
As the muscles continue to contract with exercise, the circulatory system can not provide a high enough supply of oxygen.
As the lactic acid is carried around the blood stream it impairs the body's normal function.
Lactic acid is formed in large amounts during strenuous exercise, which leads to muscle cramps, fatigue and failure.
This results in muscle fatigue.
But unfortunately by this time, most humans will have quit exercising to allow the body to re-oxygenate.
Therefore, as the body becomes more acidic, strength, endurance and over all athletic performance including weight training, all decrease.

Method used

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  • Pharmaceutical or nutraceutical composition
  • Pharmaceutical or nutraceutical composition
  • Pharmaceutical or nutraceutical composition

Examples

Experimental program
Comparison scheme
Effect test

example 1

Typical Formulations of Alkalized Compositions

[0066]Example 1 provides typical formulations of the alkalized compositions of the invention.

Formulation A

[0067]

maltodextrin25gstarch25gdi-sodium phosphate100mgdi-potassium phosphate100mgmagnesium glycerol phosphate25mg

Formulation B

[0068]

whey protein concentrate20gdi-sodium phosphate100mgdi-potassium phosphate100mgmagnesium glycerol phosphate25mgnatural vanilla2mgsucralose2mcg

Formulation C

[0069]

maltodextrin100gsoda ash1mgmagnesium glycerol phosphate15mgKre-Alkalyn creatine750mg

Formulation D

[0070]

soy bean oil5gcalcium malate25mgdi-sodium phosphate25mgtenox ™ antioxidant25mg

Formulation E

[0071]

L-glutamine500mgmagnesium stearate5mgsoda ash2mgsodium bicarbonate3mgin a gelatine capsule100mg

Formulation F

[0072]

Tribulus Terrestris extract150mgSaw Palmento extract25mgPotassium phosphate10mgSodium phosphate50mgGelatine capsule100mg

Formulation G

[0073]

Esterified Oils350 mg (consisting of cetyl myostolate &conjugated linoleic acid)di-sodium phosphate2...

example 2

Endurance and Stamina

Study

[0076]Study administering an alkalized maltodextrin (Formulation A)-vs-unalkalized maltodextrin to 12 endurance athletes in the off season phase.

Procedures

[0077]6 subjects were administered 25 grams of alkalized maltodextrin 30 minutes before exercise and 6 subjects were administered 25 grams of unalkalized maltodextrin for 2 weeks. No changes were made to diet or off season training.

[0078]Endurance & Stamina levels were tested at the beginning of the study and every day for two weeks.

[0079]The testing equipment used were Life Fitness computerized bicycles. These systems are able to monitor heat beat and revolutions per minute.

Results

[0080]The pre test showed that the unalkalized maltodextrin group was in a bit better shape then the alkalized maltodextrin group. The alkalized maltodextrin group was barely able to work up to and maintain a level 4, at 100 rpms for 20 minutes while the unalkalized maltodextrin group could maintain a level 4, 100 rpms for 20 m...

example 3

Muscle Gain

Study

[0086]Rat Study with Alkalized Protein (Formulation B)

Procedures

[0087]White male albino rats where used for this study. A control group was used along with a test group. Upon arrival to the lab both groups entered Phase I, stabilization. Stabilization started with changing their diet to a more conventional food source. Good protein and carb levels, low fat. Each rat was weighed at the start and every three days for ten weeks. Rats were randomly selected for test group and control group.

[0088]Rats were placed in a large 10 gallon glass cages that allowed movement and building of nests. Chew items were also put in the cages to help measure night activity.

[0089]Alkalized Protein Administration: Based on human studies, 10 grams per 100 kg of body weight was used. This worked out to 100 mcg / gram of rat starting weight. Alkalized protein was administered daily. The control group received protein of an acidic nature.

The Start

[0090]The starting weight of both groups varied, ...

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Abstract

The invention relates to a pharmaceutical or nutraceutical composition comprising an alkalized organic substance selected from the group comprising proteins, carbohydrates, lipids, amino acids, vitamins, therapeutic agents and mixtures thereof. Such compositions are useful for treating a range of diseases and conditions. They also give rise to beneficial physiological effects such as, for example, increasing physical strength, muscle mass and endurance.

Description

[0001]This application is a continuation of application Ser. No. 12 / 807,067 and claims the benefit of provisional application Ser. No. 61 / 275,190 filed Aug. 26, 2010.BACKGROUND OF INVENTION[0002]Many, if not most of the foodstuffs consumed by mammals are acidic in nature. This is particularly true of processed foods such as convenience foods or “junk foods”. Many foods are made more acidic during processing to improve their taste and also to facilitate preservation. Most food preservatives are more effective in a low pH environment. In addition any additives and food preservatives are themselves acidic, for example, citric acid, malic acid, ascorbic acid, phosphoric acid, benzoic acid, acetic acid and sulphur dioxide.[0003]Besides ingesting a variety of acidic products, a typical modern diet is composed almost entirely of acid-forming foods, such as animal proteins, grains, legumes, and table salt (sodium chloride). Sixty percent of table salt is a reactive chloride ion which, in so...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K31/718A61K33/00A61K33/42A23L33/15A23L35/00
CPCA61K31/718A61K33/00A61K33/42A61K31/198A61K31/337A61K36/185A61K36/889A61K36/90A61K45/06A23L29/30A23L33/105A23L33/115A23L33/15A23L33/175A23L33/30A23L33/16A23L33/185A23L33/19A23L5/00A23L33/125A61K31/661A61K38/168A61P11/06A61P19/10A61P21/00A61P21/06A61P25/00A61P25/16A61P25/28A61P29/00A61P31/12A61P31/14A61P35/00A61P3/06A61P37/02A61P37/08A61P39/00A61P9/00A61P9/06A61P9/10A61K2300/00A23V2002/00A61K35/20A61K36/899
Inventor GOLINI, JEFFREY M.
Owner GOLINI JEFFREY M