The invention discloses an automatic cargo loading and unloading and counterweight platform of an express delivery drone, which includes a platform base, a fixed support, a first manipulator, a bracket, a horizontal guide rail, a mobile slide, a second manipulator, a cargo information reader and a controller , the fixed support is set on the platform base to fix the manipulator one, and the manipulator one is under the control of the controller to load and unload the goods on the shelves in the unmanned aerial vehicle cabin; the horizontal guide rail is set on the bracket, and the mobile slide table is set On the horizontal guide rail, the manipulator 2 is set on the mobile slide table, and the cargo information reader is set on the manipulator 2. The cargo information reader transmits the scanned and read cargo information to the controller, and the controller controls the manipulator 2. Controls for counterweighting the unmanned cabin. Due to the adoption of the above-mentioned structural form, it has the functions of automatic loading and unloading of goods, reading of goods information and realizing the intelligent counterweight of goods according to the scanned data, so it is suitable for the automatic delivery platform of drones in the express delivery industry in the future.