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14 results about "Dopamine agonist" patented technology

A dopamine receptor agonist (DA) is a compound that activates dopamine receptors. There are two families of dopamine receptors, D₂-like and D₁-like, and they are all G protein-coupled receptors. D₁- and D₅-receptors belong to the D₁-like family and the D₂-like family includes D₂, D₃ and D₄ receptors. The DA are used in Parkinson’s disease and, to a lesser extent, to treat depression, hyperprolactinemia and restless leg syndrome.

Sublingual compositions for erectile dysfunction

Sublingual compositions for the treatment of erectile dysfunction (ED) comprise unique combinations of phosphodiesterase-type 5 (PDE5) inhibitors and D1 / D2 dopamine receptor agonists. In preferred embodiments, a combination of four drug actives exhibits a full range of effectiveness for ED in which there is a short and long acting PDE5 inhibitor in combination with both a dopamine agonist and a CNS hormone to provide both a physiological response and a psychological / CNS action. A treatment for ED comprises administration of sublingual compositions in the physical form of sublingual tablets.
Owner:WOODYS MEDICAL LLC

Combination therapy for a dopamine agonist

PendingUS20260144776A1Nervous disorderDigestive systemOndansetronDopamine
The application describes a method of reducing emesis caused by a dopamine agonist in a patient with depression who is treated with a dopamine agonist, comprising administering ondansetron in combination with the dopamine agonist.
Owner:ALTO NEUROSCIENCE INC

Long-acting dopamine agonist

ActiveCN309585791SDopaminePsychiatry
1. The name of the design product: long handle hair stick (Dopamine). 2. The use of the design product: for hair stick. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view.
Owner:HANGZHOU YOUYANG E-COMMERCE CO LTD

Oral octreotide administered in combination with other therapeutic agents

PendingUS20250170204A1PeptidesCyclic peptide ingredientsAcromegalyGrowth Hormone Receptor Antagonist
This invention relates to combination therapy of a subject suffering from acromegaly. The method of treatment comprises administration to the subject of a therapeutically effective amount of oral somatostatin receptor ligand (SRL) e.g. octreotide in combination with a therapeutically effective amount of a dopamine agonist and / or a growth hormone receptor antagonist and / or a selective estrogen receptor modulator (SERM) and / or a 2nd somatostatin receptor ligand (SRL).
Owner:AMYLIN PHARMACEUTICALS INC

Combination therapy for a dopamine agonist

ActiveUS12521374B1Nervous disorderDigestive systemOndansetronDopamine
The application describes a method of reducing emesis caused by a dopamine agonist in a patient with depression who is treated with a dopamine agonist, comprising administering ondansetron in combination with the dopamine agonist.
Owner:ALTO NEUROSCIENCE INC

Quinolinone double-ligand derivative and application thereof as D2R agonist

The invention discloses a quinolinone double-ligand derivative and an application of the quinolinone double-ligand derivative as a dopamine D2R agonist. According to the invention, n-propyl indene-2-amine is used as a normal ligand fragment, quinolinone or indolone is used as an allosteric ligand fragment, and an intermediate LINKER part is connected by a methylene carbon chain and a cyclohexyl carbon chain with different lengths to obtain the dopamine D2R agonist as shown in a formula (1) and a formula (2). According to the invention, the functional activity of all compounds on D2R on a G protein dependent signaling pathway is tested through a GloSensor cAMP accumulation experiment. Pharmacological results show that all the synthesized target compounds have good agonistic activity on D2R, that is, the target compounds of the invention are D2R agonists. # imgabs0 #
Owner:CHANGZHOU UNIV

Hippocampus and pilose antler essence health-care cream

The invention relates to the technical field of yang tonifying, and discloses a hippocampus and pilose antler essence health-care paste which mainly comprises 30 g of actinolite, 30 g of morinda officinalis, 5 g of pilose antler, 5 g of hippocampus, 30 g of radix cyathulae, 50 g of herba epimedii, 15 g of cynomorium songaricum, 15 g of eucommia ulmoides, 15 g of semen cuscutae, 30 g of schisandra chinensis, 30 g of ligusticum wallichii, 30 g of cinnamon, 15 g of ginger, 50 g of cistanche, 30 g of salvia miltiorrhiza, 30 g of clove, 30 g of fructus cnidii, 50 g of radix polygoni multiflori preparata, 15 g of rhizoma polygonati and 30 g of rhizoma acori graminei Compared with other products in the market, the health-care wine does not contain nafil, ramine, caine and oxetine drugs, also contains the components such as a phosphodiesterase (PDE5) inhibitor, an adrenergic receptor blocker, a dopamine agonist, an anesthetic and capsaicin, does not cause damage to the body after being drunk, does not affect the effect, and is safe and reliable. Adverse reactions such as dizziness, headache, abdominal distension, nausea, persistent excitation, sexual overdraft and the like are not generated.
Owner:刘华建

Therapeutic agent for neurodegenerative disorder

The present invention addresses the problem of providing a medicine that, despite of being a non-ergot dopamine agonist (DA), reduces the risk of the drowsiness side effect, and exhibits an excellent therapeutic effect on neurodegenerative disorders such as Parkinson's disease (PD). The present invention relates to a pharmaceutical composition for treating neurodegenerative diseases such as Parkinson's disease, the pharmaceutical composition comprising 1-{[(4aR,6R,8aR)-2-amino-3-cyano-8-methyl-4,4a,5,6,7,8,8a,9-octahydrothieno[3,2-g]quinolin-6-yl]carbonyl}-3-[2-(dimethylamino)ethyl]-1-propylurea or a pharmacologically acceptable salt thereof. The pharmaceutical composition is characterized by being orally administered at a daily dose of 0.25 mg to 2 mg in terms of free form.
Owner:KISSEI PHARMACEUTICAL CO LTD

Combination therapy for a dopamine agonist

ActiveUS12648934B2Nervous disorderDigestive systemOndansetronDopamine
The application describes a method of reducing emesis caused by a dopamine agonist in a patient with depression who is treated with a dopamine agonist, comprising administering ondansetron in combination with the dopamine agonist.
Owner:ALTO NEUROSCIENCE INC

Use of nicotinic acetylcholine receptor alpha 7 activators

ActiveCN110051670BOrganic active ingredientsNervous disorderDopamineDopamine agonist
The present invention relates to the use of nicotinic acetylcholine receptor alpha 7 activators, in particular to the use of nicotinic acetylcholine receptor alpha 7 agonists for the treatment, prevention or delay of progression of dyskinesia associated with dopamine agonist therapy in Parkinson's disease.
Owner:NOVARTIS AG

Combination therapy for a dopamine agonist

ActiveUS20260069573A1Nervous disorderDigestive systemOndansetronDopamine
The application describes a method of reducing emesis caused by a dopamine agonist in a patient with depression who is treated with a dopamine agonist, comprising administering ondansetron in combination with the dopamine agonist.
Owner:ALTO NEUROSCIENCE INC