5 results about "Sedative agent" patented technology

A system and a method provide closed-loop sedation, anesthesia, or analgesia by monitoring EEG and automatically adjusting delivery of sedative, anesthetic, and / or analgesic drugs to maintain a desired or predetermined level of cortical at all echelons of care. The system and the method further monitor a subject's cortical activity to detect occurrence of burst suppression which can be indicative of unsafe depth of anesthesia or sedation. Further, the system and the method provide for alteration or cessation of administration of anesthesia or sedation based on the occurrence of burst suppression to mitigate harm to the subject.

The present disclosure relates to novel sulfate salt forms of 2-(5-methoxyisochroman-1-yl)-4,5-dihydro-1H-imidazole (I). Compound (I) is a selective alpha2A adrenoceptor agonist and is useful in the treatment of anxiety, and for use as a sedative or analgesic agent, and other diseases were alpha2A agonism is desired.

The present invention provides a method for producing a slag forming sedative that utilizes at least one of tar sludge and sludge as a slag forming sedative in converters and slag discharge areas, and a method for sedating slag forming. [Solution] A method for producing a slag forming sedative, comprising a heavy-forming step of heating and drying liquid waste containing at least one of tar sludge and sludge in a low-oxygen atmosphere to increase its weight, and a method for slag forming, comprising a sedation step of adding the produced slag forming sedative to the slag forming to sedate the forming.

The present application provides a programmed drug release composite microneedle, which is composed of a drug-loaded needle tip layer and a base layer, can realize rapid release of analgesic drugs and slow release of sedative drugs, and the two drugs synergistically play the roles of analgesia, sedation and improvement of mood; through a plurality of experiments, it is verified that the microneedle has good biocompatibility, no skin irritation, no long-term toxicity to main organs, and non-invasive and convenient operation, solves many defects of traditional analgesic and sedative dosage forms, and provides a new effective path for long-term home intervention of chronic pain patients.

The application discloses a rapid detection method of non-opiate sedative agent methaqualone, and belongs to the technical field of forensic toxicant safety detection. The method comprises the following steps: firstly, preparing melamine foam material of surface modified dopamine-polyacetylene imine copolymer; then, cutting the melamine foam material and placing it into the head of a pipette gun, compacting to obtain a treated head; enriching methaqualone in the head; and detecting the sample by ion mobility spectrometry after ionization of the sample.