The invention relates to an intelligent part inquiry and quotation system which comprises a server side, an inquiry side and a quotation side, and the inquiry side and the quotation side are in communication connection with the server side. And the server side comprises a data information acquisition module, a spare and accessory part information database, a data processing module, a quotation management module, a quotation information database and an intelligent maintenance module. The inquiry side comprises an inquiry page, and a vehicle identification code input box, a spare and accessory part name input box, a spare and accessory part information input box and a quotation information box are arranged on the inquiry page. The quotation side comprises a quotation page, and a part quotation information input box is arranged on the quotation page. The invention further discloses an intelligent part inquiry and quotation method. The method comprises the steps of data acquisition, data processing, automatic quotation, intelligent maintenance and the like. According to the invention, an intelligent data maintenance scheme is adopted to improve the inquiry information identification and fault-tolerant capability of the system, and the method has the characteristics of inquiry information identification, strong fault-tolerant capability, high efficiency, convenience, intelligence and the like.