The invention relates to video devices, monitoring devices and pick-up lens devices, in particular to a four-element high-resolution day-and-night dual-purpose multipoint varifocal lens. The multipoint varifocal lens in a novel four-element structural style has the advantages of high optical zoom ratio, large focal length, large aperture, high resolution, wide light spectrum, confocal property and the like; and the multipoint varifocal lens also has the characteristic of small structural length. The light path is composed of a front fixing element (A), an optical zooming element (B), a back fixing element (D) and a compensation element (E). Since the optical zooming element (B) and the compensation element (E) correspondingly move back and forth along the optical axis, the focal length of the optical system can be conveniently changed. In the light path design process, the focal power of the four elements are reasonably distributed, so that the optical lens has the performance indexes of high optical zoom ratio, large focal length and large relative aperture.