The invention provides a hand intelligent 3D information acquisition and measurement device and method. The acquisition and measurement device comprises an image acquisition device and a bearing plate, and the image acquisition device and the bearing plate are oppositely arranged; the bearing plate is used for bearing hands; the image acquisition device is arranged on the rotating device, and an included angle gamma is formed between the optical axis of the image acquisition device and the rotating plane. A mode of forming an included angle between a camera optical axis and a rotating plane isproposed for the first time to simultaneously improve the synthesis speed and synthesis precision of the hand 3D model. By optimizing the positions of pictures acquired by the camera, it is guaranteed that the 3D synthesis speed and synthesis precision of the hand can be improved at the same time; and when the position is optimized, angle measurement and target size measurement are not needed, sothat the applicability is higher.