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Iron replenisher with control released iron and its preparing method and use

A slow-release iron supplement technology, applied in food preparation, application, food science, etc., can solve problems such as cell membrane damage, achieve the effects of improving absorption and utilization, convenient use, and simple process flow

Inactive Publication Date: 2008-01-30
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, judging from the currently used iron fortifiers, those with good solubility and high bioavailability are often more likely to change the color and taste of food
Moreover, iron supplements such as ferrous sulfate and ferrous gluconate are often accompanied by side effects such as gastrointestinal irritation and rusty taste, and iron (II) can produce endogenous free radicals in the body, leading to cell membrane damage caused by cell membrane lipid peroxidation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1) Grinding the clinoptilolite produced in Jinyun, Zhejiang to 500 mesh, adding water and stirring evenly to make a suspension slurry with a concentration of 10%;

[0026] 2) Slowly add ferrous chloride having an iron content of 2% by weight of zeolite into the suspension slurry in step 1) under stirring, detect and adjust the pH value of the slurry to 3.0, and react at room temperature for 4 hours;

[0027] 3) The pH value of the detection step 2) is adjusted with 0.5moL / L sodium carbonate aqueous solution, so that the pH value of the slurry is 7.0; washed 4 times, filtered and dehydrated;

[0028] 4) The filter cake obtained in step 3) was dried and crushed to 600 meshes to obtain a controlled and sustained-release iron supplement, and the content of iron in the zeolite was 2% by weight percentage.

[0029] Effects of different iron sources on laying performance and egg iron content of laying hens:

[0030] Choose 450 chickens of 380-day-old healthy Roman laying hens...

Embodiment 2

[0034] 1) Grinding a commercially available ZSM-5 zeolite molecular sieve to 300 mesh, adding water and stirring evenly to make a suspension slurry with a concentration of 5%;

[0035]2) Slowly add ferrous nitrate with an iron content of 5% by weight of zeolite into the suspension slurry in step 1) under stirring, detect and adjust the pH value of the slurry to 4.5, and react at room temperature for 6 hours;

[0036] 3) The pH value of the detection step 2) is adjusted with a 10moL / L aqueous sodium hydroxide solution to make the pH value of the slurry 7.5; washed with water for 3 times, filtered and dehydrated;

[0037] 4) The filter cake obtained in Step 1 and 3) was dried and crushed to 300 meshes to obtain a controlled-release iron supplement, and the content of iron in the zeolite was 5% by weight percentage.

[0038] Effects of different iron sources on growth, metabolism and environment in suckling piglets:

[0039] A total of 15 litters of 15 hybrid sows were selected ...

Embodiment 3

[0043] Preparation: Mesoporous molecular sieve MCM-41 was prepared according to the method of "Modification and Characterization of Mesoporous Molecular Sieve MCM-41 under Mild Conditions" (Zheng Shan, Gao Lian, Guo Jingkun. Journal of Inorganic Materials, 2000, 15(5): 844-848). 41.

[0044] 1) Grind the mesoporous molecular sieve MCM-41 obtained in the preparatory step to 300 mesh, add water and stir evenly, and make a suspension slurry with a concentration of 1%;

[0045] 2) Slowly add ferrous glycinate with an iron content of 10% by weight of MCM-41 into the suspension slurry in step 1) under stirring, detect and adjust the pH value of the slurry to 6.5, and react at room temperature for 10 hours;

[0046] 3) The pH value of the detection step 2) is adjusted with 5moL / L potassium hydroxide aqueous solution, so that the pH value of the slurry is 8.5; washed 5 times with water, and centrifuged for dehydration;

[0047] 4) The filter cake obtained in step 3) was dried and cru...

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PUM

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Abstract

The present invention discloses iron replenisher with control released iron and its preparation process and use. The iron replenisher is zeolite containing active iron in 1.5-10 wt%. The preparation process includes the adsorption and ion exchange reaction between bivalent iron salt and zeolite, filtering, drying and crushing to obtain zeolite containing active iron. Supporting iron onto zeolite, which possesses excellent biocompatibility, excellent gastrointestinal mucous membrane affinity, regular pore canal structures and cage spaces, high surface activity and great specific surface area, can obtain controlled releasing of iron and raise utilization of iron. The control released iron preparation may be used as iron replenisher for human body and animal.

Description

technical field [0001] The invention relates to an iron supplement of controlled and sustained release type iron, a preparation method and application thereof. Background technique [0002] Iron is an essential trace element for animals. It is an essential component of hemoglobin and myoglobin. The activity of oxidase is closely related. Iron participates in the normal transport of oxygen in body tissues, directly affects the energy and protein metabolism of the body, and also affects the immune function and reproductive performance of animals. The iron content in conventional feed is relatively high, and in terms of quantity alone, it can already meet the needs of animals. However, the utilization rate of iron in plant feed is extremely low, and the degree of intensification of the breeding industry is getting higher and higher. The efforts in both breeding and nutrition have greatly increased the growth rate of livestock and poultry. Therefore, some iron must be artific...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/26A61K47/02A61P3/02A23K1/16A23L1/304A23K20/20A23K20/28
Inventor 胡彩虹夏枚生熊莉
Owner ZHEJIANG UNIV
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