Compound panax notoginseng cataplasma

Abstract

The invention relates to a compound external preparation of pseudo-ginseng, that is cataplasm, which is prepared by raw materials of extract (dry extract powder) of pseudo-ginseng, preserved Yunnan Kusnezoff monkshood, paris and psammosilene tunicoides with proper accessories. The compound cataplasm of the invention comprises a backing layer, a body containing ointment and a cover underlayer. The containing ointment body as a main part is formed by extract of pseudo-ginseng, preserved Yunnan Kusnezoff monkshood, paris and psammosilene tunicoides, with accessories such as adhesive, filer, penetration enhancers, humectant, etc., based on a predetermined ratio. The cataplasm has advantages of fast absorption, good moisture retention and ventilation property, and is comfortable for using. In addition, the product of the invention is convenient for using, has little acrimony to skin and has high compliance for patient.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a compound notoginseng (external dosage form) cataplasm for treating various pains and having certain anti-inflammatory, antipyretic and local anesthetic effects. Background technique [0002] Catapult is an external preparation that dissolves or mixes drugs in a natural or synthetic water-soluble polymer matrix and spreads them on the backing material for sticking on the skin. It can act systemically or locally through transdermal absorption. It is also a transdermal drug delivery preparation, and its prototype is "poultica". Due to the rapid development of modern fine chemical industry and polymer material science, more excipients with superior performance have been provided for pharmacy. Therefore, cataplasm was first successfully developed by Japan in the 1970s. Up to now, a large number of cataplasms have been launched in developed countries such as Europe, America and J...

AI Technical Summary

Problems solved by technology

Because raw powder of medicinal materials is used as medicine, and the active ingredients of Aconitum Diancao, Chonglou, and Jintiesuo in the prescription have obvious liver first-pass effects. In addition, Aconitum Diancao, Chonglou, and Jintiesuo in the prescription are toxic traditional Chinese medicines, so the two The disadvantage of this preparation product is that there are large gastrointestinal side effects when taken orally, and some patients may experience reactions such as nausea, vomiting, and gastrointestinal discomfort, and the bioavailability is low, which limits the wide application of the drug in clinical practice to some extent.

Although the four medicinal materials in the liniment, Sanqi, Diancaowu, Jintiesuo, and Zhonglou, are extracted by percolation with 60% ethanol, the drug loading of the liniment is small, and the drug is easily wiped off by clothes, etc., and the effect is not long-lasting. Therapeutic effect can be achieved by repeated administration

In addition, since the liniment contains a large amount of ethanol, patients who are allergic to ethanol are prone to allergic reactions

Secondly, the liniment has poor stability. After standing for a period of time, there will be gelatinous substances deposited on the bottom of the bottle, which will have a certain impact on the quality, image and effect of the product; and because the use of the liniment will pollute the clothes, it is inconvenient to use and poor patient compliance.

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