Antibiotic packaging material with release controlling function

Abstract

The invention relates to a preparation method of an aceptic packaging material with a release-controlling function, particularly comprising three steps: firstly, a chemical surface modifying method is adopted to cause the surface of polymer packaging materials to form certain amount of dissociable functional groups such as carboxyl, sulfonic group, amidine, etc; meanwhile, antibacterial agent nisin is coated inside chitosan hydrogel microspheres which employ carboxyl polyethylene glycol as crosslinking agent, employ water-soluble carbodiimide hydrochloride as coupling agent and have particle size smaller than 100nm; in mixed solvent with 100 / 0-50 / 50 of water / ethanol, the drug-coating chitosan microspheres through ultrasonic stirring processing is 'fixed' on the surface of modified polymer thin films through electrostatic absorption between cathodic anodic ion. Since the surface modifying methods and chitosan hydrogel formulas are different, the releasable nisin amount can reach 0.5-40 Mu g / cm<2>.

Description

technical field

[0001] The invention relates to a preparation method of an antibacterial packaging material with controlled release function for food packaging. The purpose of food packaging is to provide a reliable guarantee for the production, distribution and consumption of food. On the premise of ensuring safety, improving the senses of packaged food and prolonging the shelf life is the eternal pursuit of food packaging technology. Plastic flexible packaging and containers occupy a dominant position in the field of food packaging, but the current existing plastic packaging materials can only passively provide physical protection for the packaged food. Using active packaging technology to realize the controlled release of active substances—antibacterial agents is expected to achieve safe and efficient purposes. Existing research mainly adopts the method of surface coating and intelligent blending to achieve the above goals, but the experimental results are not very satisfa...