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Formulation for increasing calcium absorption

A technology for calcium absorption and preparation, applied in the field of calcium supplementation products, can solve the problems of slow absorption, difficult absorption of calcium supplementation by the human body, and large loss of calcium

Inactive Publication Date: 2008-12-17
王冰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Domestic and foreign medical circles agree that the main cause of osteoporosis and bone hyperplasia is the long-term calcium deficiency in the human body. For this disease, calcium supplementation is mainly used for prevention and treatment at present. The existing calcium supplementation in China is active. Calcium is ionized calcium, calcium gluconate, calcium lactate, calcium tablets, etc. These calcium supplements are used to treat osteoporosis and hyperplasia, but there are the following problems: First, some calcium supplements are not easily absorbed by the body, such as oysters, mussels, etc. The shell is used as the raw material and calcined at high temperature to make a calcium mixture. Its main components are calcium oxide, calcium hydroxide and a small amount of calcium carbonate. These inorganic calcium are not easy to be absorbed by the human body, and their toxicity is relatively high.
At present, most calcium supplements or nutrients use calcium carbonate and vitamin D. Calcium carbonate is insoluble in water, and part of it becomes ionized calcium under the action of gastric acid, which is slow to absorb and has a large amount of loss.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Calcium acetate 200g

[0021] Glucosamine Hydrochloride 40g

[0022] Casein Phosphopeptide 20g

[0023] Epimedium Extract 40g

[0024] Drynaria Extract 40g

[0025] Microcrystalline Cellulose 15g

[0026] Magnesium Stearate 2.5g

[0027]

[0028] Makes 1000 pieces

[0029] Preparation method: mix calcium acetate, glucosamine hydrochloride, casein phosphopeptide, epimedium extract, drynaria drynaria extract and microcrystalline cellulose evenly, use 75% ethanol as wetting agent, make soft material, and granulate , dried at 80±10°C, granulated, added with magnesium stearate, mixed evenly, pressed into tablets or coated with film coating according to conventional coating operations.

Embodiment 2

[0031] Calcium acetate 350g

[0032] Glucosamine Hydrochloride 125g

[0033] Casein Phosphopeptide 20g

[0034] Epimedium Extract 50g

[0035] Drynaria Extract 37.5g

[0036] Microcrystalline Cellulose 15g

[0037] Magnesium Stearate 2.5g

[0038]

[0039] Made into 000 pieces

[0040] Preparation method: mix calcium acetate, glucosamine hydrochloride, casein phosphopeptide, epimedium extract, drynaria drynaria extract and microcrystalline cellulose evenly, use 75% ethanol as wetting agent, make soft material, and granulate , dried at 80±10°C, granulated, added with magnesium stearate, mixed evenly, pressed into tablets or coated with film coating according to conventional coating operations.

Embodiment 3

[0042] Calcium acetate 800g

[0043] Glucosamine Hydrochloride 400g

[0044] Casein Phosphopeptide 20g

[0045] Epimedium Extract 100g

[0046] Drynaria Extract 100g

[0047] Microcrystalline Cellulose 360g

[0048] Magnesium Stearate 18g

[0049]

[0050] Makes 1000 pieces

[0051] Preparation method: mix calcium acetate, glucosamine hydrochloride, casein phosphopeptide, epimedium extract, drynaria drynaria extract and microcrystalline cellulose evenly, use 75% ethanol as wetting agent, make soft material, and granulate , dried at 80±10°C, granulated, added with magnesium stearate, mixed evenly, pressed into tablets or coated with film coating according to conventional coating operations.

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PUM

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Abstract

A preparation for increasing the calcium absorption, which is provided by the invention, relates to a calcium supplement product, in particular to a preparation which can supplement calcium. The calcium supplement preparation of the invention is mainly prepared by main raw materials of calcium acetate, glucosamine hydrochloride, CPPs, extracts of epimedium and extracts of rhizoma drynariae, and is characterized in that the ratio of the main raw materials is 5 portions to 40 portions of calcium acetate, 1 portion to 20 portions of glucosamine hydrochloride, 0.5 portion to 3 portions of CPPs, 1 portion to 5 portions of extracts of epimedium, 1 portion to 5 portions of extracts of rhizoma drynariae and 0.1 portion to 25 portions of auxiliary material. The preparation of the invention can realize the effects of promoting calcium absorption, improving bone metabolism and bone nutrition and increasing the bone density.

Description

technical field [0001] The invention relates to a calcium supplement product, in particular to a calcium supplement preparation. Background technique [0002] Domestic and foreign medical circles agree that the main cause of osteoporosis and bone hyperplasia is the long-term calcium deficiency in the human body. For this disease, calcium supplementation is mainly used for prevention and treatment at present. The existing calcium supplementation in China is active. Calcium is ionized calcium, calcium gluconate, calcium lactate, calcium tablets, etc. These calcium supplements are used to treat osteoporosis and hyperplasia, but there are the following problems: First, some calcium supplements are not easily absorbed by the body, such as oysters, mussels, etc. The shell is used as the raw material and calcined at high temperature to make a calcium mixture. Its main components are calcium oxide, calcium hydroxide and a small amount of calcium carbonate. These inorganic calcium ar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/16A61K38/10A61K9/48A61K9/20A61K9/10A61K9/16A61K9/28A61K47/38A61K47/36A61K47/24A61K47/46A61P3/02A61P19/10A61K31/7008A61K31/19A61K36/296
Inventor 王冰刘晓凯张永胜杜元英
Owner 王冰
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