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Sucralose microcapsule and preparation method thereof

A technology of sucralose and microcapsules, which is applied in the field of sucralose microcapsules and its preparation, can solve the problems of loss of sweetness, difficulty in controlling the amount of use, and changes in the quality of sweeteners, so as to ensure no loss of sweetness , the chemical and physical properties do not change, and the effect of preventing deliquescence

Inactive Publication Date: 2009-12-02
南京仕浪药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The compound sweetener of sucralose is easy to react with moisture in the air and deliquesce during storage, resulting in changes in the quality of the sweetener and loss of sweetness; and the sweetness of sucralose is 600-800 times that of ordinary sucrose , that is, 1 gram is the sweetness of more than 600 grams of ordinary white sugar, so it is difficult to control the amount used during use

Method used

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  • Sucralose microcapsule and preparation method thereof
  • Sucralose microcapsule and preparation method thereof
  • Sucralose microcapsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] (1) Preparation of cystic heart:

[0075] Main ingredient: Sucralose 2.5%

[0076] Diluent: Mannitol 50%

[0077] Sorbitol 40%

[0078] Binder: Hypromellose 0.4%

[0079] Wetting agent: appropriate amount of distilled water

[0080] Preparation process:

[0081] 1. Take sucralose and pass it through a 60-mesh sieve; take mannitol and sorbitol and pulverize it through a 80-mesh sieve;

[0082] 2. Weigh the prescription amount of excipients and mix them evenly with sucralose according to the principle of equal increase, and pass through an 80-mesh sieve;

[0083] 3. Add hydroxypropyl cellulose to the above mixed powder to prepare soft material, pass through 80-mesh sieve to make wet granules; bake at 45°C-50°C for 2-3 hours, pass through 60-mesh sieve and vibrate to granulate;

[0084] (2) Preparation of microcapsules:

[0085] Ethylcellulose 6.65%

[0086] Polyethylene 0.45%

[0087] Proper amount of cycloethane

[0088] Preparation process:

[0089] S...

Embodiment 2

[0091] (1) Preparation of cystic heart:

[0092] Main ingredient: Sucralose 2%

[0093] Diluent: Mannitol 50%

[0094] Maltitol 45%

[0095] Binder: Hypromellose 0.4%

[0096] Wetting agent: appropriate amount of distilled water

[0097] The capsule core was prepared according to the preparation method described in Example 1.

[0098] (2) Preparation of microcapsules:

[0099] Ethylcellulose 2.15%

[0100] Polyethylene 0.45%

[0101] Proper amount of cycloethane

[0102] Microcapsules were prepared according to the preparation method described in Example 1.

Embodiment 3

[0104] (1) Preparation of cystic heart:

[0105] Main ingredient: Sucralose 2.8%

[0106] Diluent: Mannitol 45%

[0107] Sorbitol 45%

[0108] Binder: Hypromellose 0.2%

[0109] Wetting agent: appropriate amount of distilled water

[0110] The capsule core was prepared according to the preparation method described in Example 1.

[0111] (2) Preparation of microcapsules:

[0112] Ethylcellulose 4%

[0113] Polyethylene 3%

[0114] Proper amount of cycloethane

[0115] Microcapsules were prepared according to the preparation method described in Example 1.

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Abstract

The invention discloses a sucralose microcapsule and a preparation method thereof; the microcapsule comprises a capsule core and a capsule wall material, which is characterized in that the capsule core of the microcapsules uses sucralose as the main drug with the content being 2%-3%; a thinner is formed by combining any two of mannitol, sorbitol, erythritol, maltitol, xylitol, glucose, dextrine, aspartame, acesulfame potassium and fructose with the contents being respectively 40%-50%; and the dosage of a binder is 0.2%-0.6%; the capsule wall material mainly uses ethyl cellulose and polyethene, the dosage of ethyl cellulose is 2%-10%, and the dosage of polyethene is 0.4-5%.The sucralose microcapsules of the invention can prevent sucralose grain raw material from deliquescing, oxidizing and deteriorating, thus preventing the sweet taste from losing, and the sucralose microcapsules can be released at a slow and constant speed, thus ensuring the evenness of the sweet taste of the granule beverage; the preparation method of the microcapsule is simple with low cost, which is suitable for large scale continuous production, and the finished product has high encapsulation rate and high yield.

Description

Technical field: [0001] The invention relates to a sucralose microcapsule and a preparation method thereof. In the invention, ethyl cellulose and polyethylene are selected as capsule materials for production. Background technique: [0002] In 1957, Moore Business patented the application of spray drying method for microencapsulation. This patent requires that the mixture of heartwood and capsule material be passed into a heating chamber or a cooling chamber to rapidly remove solvent or solidify to make microcapsules. The method comprises the following three steps: 1. preparing a concentrated solution of a carrier or a shell material; 2. emulsifying the encapsulated heartwood in the solution of the shell material; 3. spraying and drying. However, the patent does not specify the solution concentration, emulsification steps and drying time, and the experimental results cannot be reproduced. The present invention has discussed this aspect in detail, and finally found that the b...

Claims

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Application Information

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IPC IPC(8): A23L1/236A23L27/30
Inventor 毕贤魏倩叶敏敏蒋栋梁王洁
Owner 南京仕浪药业有限公司
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