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Method for measuring main carbonyl compounds in main stream cigarette smoke

A technology for mainstream smoke and carbonyl compounds of cigarettes, applied in measurement devices, instruments, scientific instruments, etc., can solve problems such as affecting the accuracy of test results, increasing consumption of organic solvents, loss of target compounds, etc. The effect of improving detection efficiency and reducing pollution

Active Publication Date: 2010-11-03
ZHENGZHOU TOBACCO RES INST OF CNTC
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  • Abstract
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AI Technical Summary

Problems solved by technology

At present, the detection of main carbonyl compounds in cigarette mainstream smoke generally adopts the high performance liquid chromatography method stipulated in "YC / T254-2008". It is processed by adding derivatization reagents, and needs to be left overnight in a vacuum drying oven, which takes a long time, so it is easy to cause the loss of target compounds during batch sample analysis, affecting the accuracy of test results, and the detection efficiency is low
At the same time, the longer detection period also increases the consumption of organic solvents, causing environmental pollution

Method used

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  • Method for measuring main carbonyl compounds in main stream cigarette smoke
  • Method for measuring main carbonyl compounds in main stream cigarette smoke
  • Method for measuring main carbonyl compounds in main stream cigarette smoke

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Embodiment

[0032] 1. Reagents and instruments

[0033] Reagents: standard products of formaldehyde, acetaldehyde, acetone, acrolein, propionaldehyde, crotonaldehyde, 2-butanone, and 2,4-dinitrophenylhydrazone derivatives of butyraldehyde, purchased from TCI Company; acetonitrile, purchased from Germany CNW Company; ethyl acetate was purchased from Merck, Germany; absolute ethanol was purchased from ROE Company in the United States; the above reagents were all HPLC pure. All experimental water was deionized water treated by an ultrapure water instrument; 2,4-dinitrophenylhydrazine (DNPH) was an analytically pure reagent; phosphoric acid was an analytically pure reagent; aminomethane was an analytically pure reagent.

[0034] Instruments: SM450 20-channel linear smoking machine; Agilent1200 high performance liquid chromatography; ultraviolet detector (VWD); quaternary solvent manager; Swiss Mettler company AE163 electronic balance with a sensitivity of 0.0001g.

[0035] 2. Utilize the ass...

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Abstract

The invention discloses a method for measuring main carbonyl compounds in main stream cigarette smoke, which comprises the following steps of: gathering the main carbonyl compounds in the main stream cigarette smoke with solution, detecting the main carbonyl compounds with a high performance liquid chromatograph in combination with an ultraviolet detector, and quantitatively analyzing the main carbonyl compounds in the main stream cigarette smoke by adopting an external reference method. As the main carbonyl compounds in the main stream cigarette smoke is gathered with the solution, the measurement method provided by the invention has the advantages of greatly improving detection efficiency, simultaneously reducing the loss of an organic solvent, reducing pollution to the environment and fast, efficiently and accurately measuring the content of the main carbonyl compounds in the main stream cigarette smoke, along with simple and convenient operation, high accuracy and sensitivity, high repeatability, and short detection time, namely, a detection period only comprises about 35 minutes.

Description

technical field [0001] The invention relates to the technical field of physical and chemical testing of cigarette mainstream smoke, in particular to a method for measuring main carbonyl compounds in cigarette mainstream smoke. Background technique [0002] Carbonyl compounds in cigarette mainstream smoke are an important class of harmful components in cigarette mainstream smoke, and have been included in the list of 46 harmful components of the Canadian government and the list of control components recommended by the WHO "Tobacco Product Regulation Research Group". Therefore, it is accurate Determining the content of main carbonyl compounds in cigarette mainstream smoke is of great significance for evaluating the harmfulness of cigarettes. At present, the detection of main carbonyl compounds in cigarette mainstream smoke generally adopts the high performance liquid chromatography method stipulated in "YC / T254-2008". It is processed by adding derivatization reagents, and it ...

Claims

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Application Information

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IPC IPC(8): G01N30/02G01N30/06
Inventor 张洪非侯宏卫庞永强姜兴益唐纲岭陈再根胡清源
Owner ZHENGZHOU TOBACCO RES INST OF CNTC
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