Preparation method of solid water-soluble lead-removed propolis

Abstract

The invention relates to a preparation method of solid water-soluble lead-removed propolis, which belongs to the field of deep processing technology of proplis. The propolis is mainly prepared by the following steps of: adding 50 to 90 percent ethanol into 10 to 50 weight parts of propolis raw powder; stirring at normal temperature and leaching for 6 to 24 hours; lowering the temperature to 0 to 8 DEG C with circulating cold saline and performing cold leaching for 2 to 12 hours; centrifugally filtering at the speed of between 1,000 and 6,000 rpm; performing chromatography on filtrate by usingan acid cation exchange resin chromatographic column; decompressing chromatographic solution and removing the ethanol so as to obtain concentrated solution with the relative density of 1.28; dissolving the concentrated solution in purified aqueous solution which contains 5 to 50 percent of starch glycolipid; emulsifying by using a homogenizer or a colloid mill; and performing spray drying or vacuum decompression drying on emulsified liquid so as to obtain the solid water-soluble propolis. Detection on the propolis produced by the preparation method indicates that the total flavonoid content of the propolis is more than or equal to 13.86 mg / g and the lead content is less than or equal to 0.03 ppm, wherein the total flavonoid serves as a marking component.

Description

technical field [0001] The invention relates to the field of propolis deep processing technology, in particular to a preparation method of solid water-soluble deleaded propolis. Background technique [0002] As a mixture of animal and plant secretions, propolis is a pure natural product with no toxic and side effects, and it has been proved by research to have good safety, extensive and stable disease prevention, treatment and health care effects, which has attracted the attention of scientists all over the world. Pay attention to. Domestic and foreign studies and clinical studies have confirmed that propolis has anti-infection, anti-virus, anti-tumor, anti-oxidation, anti-fatigue, anti-radiation; lowering blood fat, blood sugar, blood pressure, and cholesterol; enhancing immunity, scavenging free radicals, beautifying, promoting tissue regenerative effect. Among them, the most significant effect is that it can inhibit and kill bacteria, fungi, and viruses. It is a preciou...

AI Technical Summary

Problems solved by technology

CN1277816A announced the process of crushing at low temperature with liquid nitrogen, repeated cold immersion in ethanol, critical freeze sedimentation, rejection and filtration to remove lead, and vacuum low-temperature decompression concentration. Technology, CN101061834A has announced the technology with low-temperature crushing, ethanol dissolution, ultrasonic extraction, static, resin column adsorption to remove lead, vacuum concentration, oak storage tank brewing aging, although the above technology has carried out lead removal treatment in extraction, but does not consider Water Solubility of Propolis

Activated carbon and other adsorbents are used to adsorb and remove lead, but the effect cannot be guaranteed, and activated carbon and other adsorbents will adsorb a large amount of flavonoid active ingredients, resulting in a large loss of functional components. Use gradient alcohol extraction, freeze sedimentation and other processes to remove lead and supercritical extraction. Propolis, etc., have a good lead removal effect, but require high equipment and complicated operations, so they are not suitable for mass promotion