Medicament for treating female genital tract virus infection and preparation method of sustained-release preparation of medicament

A virus infection and reproductive tract technology, applied in the field of medicine, can solve the problems of large side effects, unsatisfactory, easy recurrence and other problems, and achieve the effect of promoting repair, accurate curative effect, and no stimulation.

Active Publication Date: 2011-04-13
海南森瑞谱生命科学药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is to provide an effective prevention and removal of female reproductive tract pathogenic viruses, definite curative effect, and no stimulation to the skin and mucous membr

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0058] One, the preparation of aloe vera yellow juice extract:

[0059] The present invention can select aloe curacao, aloe sinensis, cape aloe, aloe benli.

[0060] The bottom of the aloe leaf is cut to make the yellow juice in the aloe flow out naturally, the impurities are removed after collection, and the aloe extract is obtained, and the aloe extract is dried to obtain the aloe yellow juice extract.

[0061] Two, the preparation of aloe whole leaf extract:

[0062] After removing the gel part from the fresh leaves of Aloe Vera, homogenate the green leaf skin part, add 2 times the volume of 70% ethanol or methanol, place it in a water bath at 60°C and heat it for 2 hours, then filter, and the filtrate is centrifuged in a centrifuge, and taken The centrifuged supernatant is concentrated under reduced pressure at 60° C., and finally freeze-dried or spray-dried to obtain the whole leaf extract of the aloe vera.

[0063] 3. Preparation of natural pokeweed antiviral protein: ...

Embodiment 1

[0071] Embodiment 1, select the following raw materials in parts by weight: 10 parts of aloe yellow juice extract, 2 parts of Radix isatidis extract, 2 parts of Cactus extract, 2 parts of natural pokeweed antiviral protein, 6 parts of carrageenan, Ganoderma lucidum polysaccharide 20 parts of the mixture with mannitol, 25 parts of the mixture of aloe polysaccharide and PEG, and 3 parts of sodium alginate.

Embodiment 2

[0072] Example 2, select the following raw materials in parts by weight: 2 parts of aloe vera yellow juice extract, 0.1 part of Radix Radix isatidis extract, 0.5 part of cactus extract, 1 part of natural pokeweed antiviral protein, mutant of natural pokeweed antiviral protein 2 parts of protein, 10 parts of mixture of Xianggu polysaccharide, lactose and trehalose, 20 parts of mixture of Ganoderma lucidum polysaccharide and PEG, 20 parts of mixture of licorice polysaccharide and sorbitol, dextran, dextrin, 3 parts of xyloglucan , 6 parts of pectin, 5 parts of dextrose chlorhexidine.

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PUM

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Abstract

The invention discloses a medicament for treating female genital tract virus infection and a preparation method of a sustained-release preparation of the medicament. The medicament is prepared by the following raw materials of aloe extract, banlangen extract, cactus extract, antiviral bioactive material, an immunoreactive and stable protective agent and a polymer carrier. The preparation method comprises the steps of respectively producing the aloe extract, the banlangen extract, the cactus extract and the antiviral bioactive material into a solid substance; and then producing the solid substance with other accessories into various sustained-release preparations. The invention provides the medicament for treating the female genital tract virus infection and the preparation method of the sustained-release preparation of the medicament, wherein the medicament can effectively prevent and clear female genital tract viruses and has accurate curative effects and no stimulating effect or side effect on skin and mucosa and can be safely and reliably used for treating the female genital tract virus infection.

Description

technical field [0001] The invention belongs to the technical field of medicines, and relates to a preparation method of an external medicine and a slow-release preparation thereof, in particular to a preparation method of a medicine for treating female reproductive tract virus infection and a slow-release preparation thereof. Background technique [0002] Vaginitis and cervicitis are persistent inflammations of the female reproductive tract. They usually occur in women of reproductive age. They are the most common diseases in gynecology. They are often caused by incomplete treatment or treatment against pathogens, which makes the disease protracted. Modern medicine has confirmed that bacterial and viral infections are one of the main causes of vaginitis, cervicitis and cervical erosion. Common pathogens include: Staphylococcus, Streptococcus, E. coli, anaerobic bacteria, human papillomavirus (HPV), Chlamydia trachomatis (CT), herpes simplex virus (HSV-n), etc., among which ...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K45/06A61K38/02A61K38/21A61P31/12A61P31/20A61P31/22A61P15/00A61K31/4164A61K31/715A61K31/731A61K31/737
Inventor 张春发邓柳红杨卫帆王桂玉张耀之
Owner 海南森瑞谱生命科学药业股份有限公司
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