Microwave plasma ordinary-pressure desorption ionization source and application thereof in mass spectrum analysis

Abstract

The invention provides a microwave plasma ordinary-pressure desorption ionization source for generating plasma by applying microwave energy. The microwave plasma ordinary-pressure desorption ionization source comprises a novel microwave device capable of generating plasma, a microwave power source and a coaxial cable. The microwave device comprises an outer pipe, an inner pipe, a middle pipe and an adjusting piston, wherein the outer pipe, the middle pipe and the inner pipe are in an three-pipe coaxial structure and are respectively provided with two working gas inlets, one end of the coaxial cable is connected with the microwave power source, and the other end of the coaxial cable is coupled to the middle pipe. The ionization source can be combined with a plurality of mass spectrometers with atmosphere ports for use, can carry out desorption ionization on solid, liquid and gas samples under the ordinary-pressure environment without sample pretreatment, poisonous chemical reagents, high voltage and high-speed airflow, can shorten the detection time to the samples, can realize the real-time, on-line and non-destructive detection on the sample, can save the detection cost, cannot pollute samples and is environment-friendly; ions of obtained products are mostly molecular ions; and the obtained spectrogram is concise and distinct.

Description

[0001] technical field [0002] The invention relates to the field of analytical chemistry, in particular to an ion source for a mass spectrometer, specifically using a microwave device for generating microwave plasma using microwave energy as a microwave plasma atmospheric pressure analytical ionization source and applying the ionization source to carry out atmospheric pressure surface analytical ionization mass spectrometry analysis method. Background technique [0003] In the field of analytical chemistry, mass spectrometry has a very wide range of applications. A mass spectrometer is usually composed of a sampling system, an ion source, an ion transmission system, a mass analyzer, a detector, a data acquisition and control system, etc. The ion source, as an important part of it, has always been highly valued by people. Many different ion sources have been developed: such as electron bombardment ionization source (EI), chemical ionization source (CI), field ionization...

AI Technical Summary

Problems solved by technology

However, the above-mentioned ionization sources have certain disadvantages: ion sources based on electrospray technology require electrospray reagents, which are often toxic and pollute the environment, and require high voltage and high-speed airflow, or additional lasers , which has a certain impact on the safety of use and cost control, and requires high-pressure gas cylinders, which is not conducive to in-situ analysis

Although DART does not require solvents, it requires high voltage, high flow rate gas and heating devices. The structure is complex and the market price is too high.

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