Medicinal composition for treating diabetes mellitus
The technology of a composition and medicine is applied to the pharmaceutical composition of type II diabetes and the preparation thereof, the pharmaceutical composition for the treatment of diabetes and the field of preparation thereof, which can solve the problems of impaired insulin secretion and the like, achieve less recurrence, better hypoglycemia, The effect of reducing the economic burden
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0025] A pharmaceutical composition for treating type 2 diabetes, which is prepared from the following raw materials in proportion by weight:
[0026] Ophiopogon japonicus 20, Scutellaria baicalensis 18, Yam 18, Angelica 16, Anemarrhena 15, Japonica rice 12, Licorice 12, Astragalus 10, Atractylodes macrocephala 9, Paeoniae Alba 8, Black plum 7, Pueraria 6, Rehmannia glutinosa 6, Schisandra 4, Ginseng 4.
[0027] The preparation method of the above-mentioned pharmaceutical composition comprises the following steps: taking the above-mentioned raw materials in various parts by weight for use; After drying, pulverize into 80-mesh medicinal powder, pack into capsules, and sterilize to obtain capsule preparations.
[0028] Dosage form and usage: The dosage form of this prescription is capsule dosage form, three times a day, take half an hour before meals, 2 capsules each time, 0.5g per capsule, two weeks as a course of treatment.
Embodiment 2
[0030] zoology experiment
[0031] Experimental animals: 40 SD rats, half male and half female, weighing 160-180 g, provided by the Animal Center of Linyi People's Hospital. After the rats were adapted to feeding in the animal room for 5 days, 8 rats were randomly selected as the normal control group and fed with ordinary maintenance feed. High-sugar and high-fat feed formula: rat basic feed 68%, sucrose 10%, egg yolk powder 9%, lard 8%, cholesterol 1%, bile salt 0.2%.
Embodiment approach
[0032] Implementation method: the remaining 32 were fed with high-sugar and high-fat diet for 4 weeks. Four weeks later, rats were fasted for 24 hours, and streptozotocin (STZ) was injected intravenously at 20 mg / Kg once every two days. Choose 24 successful rats of modeling, be divided into 3 groups at random, 8 in every group, i.e. model group (do not use any medicine), the embodiment of the present invention 1 medicine group 10mg / Kg, contrast medicine group: use metformin hydrochloride ( 10mg / kg), the way of administration is oral, and it is taken half an hour before meals every day. Tested after 10 days of continuous use.
[0033] Statistical analysis: The data are represented by x ± s, and SPSS17.0 statistical software is used for data analysis. The comparison between multiple groups is by analysis of variance, and the comparison between two groups is by t test. P<0.05 is statistically significant.
[0034] Treatment effect: The biochemical indicators of fasting plasma ...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com