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Traditional Chinese medicine composition for treating kidney deficiency and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating kidney deficiency and its preparation, can solve the problems of difficult extraction of active components in medicinal materials, failure to obtain reasonable utilization, etc. The effect of improving function and pharmacological activity

Active Publication Date: 2012-10-03
GUANGDONG HUANAN PHARMACEUTICAL GROUP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention is an improved invention on the basis of the patent of "Chinese medicine composition, preparation and preparation process with aphrodisiac effect" (patent application number CN93101612.6). 75% ethanol impregnation extraction, the dregs are then extracted with water together with other medicinal materials and concentrated into an extract; due to the hard texture of velvet antler, it is difficult to extract the active ingredients in the medicinal materials completely by using the extraction process of the existing technology. After extraction, velvet antler and hippocampus medicine The slag is discarded and cannot be used reasonably
Through the inquiry of the traditional Chinese medicine preparations containing velvet and hippocampus in the "Chinese Pharmacopoeia" and the national standard of Chinese patent medicine preparations, and the standards issued by the Ministry of Health, no existing Chinese medicine varieties of velvet and hippocampus are made by alcohol extraction (or water extraction) After the extract or dry paste powder, the medicinal dregs are crushed into powder and used as medicine; through patent and literature search, there is no such thing as extracting velvet and hippocampus with alcohol (or water extraction) to make extract or dry paste powder, and then crushing the medicinal dregs Relevant patents and literature reports on powdered medicine

Method used

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  • Traditional Chinese medicine composition for treating kidney deficiency and preparation method thereof
  • Traditional Chinese medicine composition for treating kidney deficiency and preparation method thereof
  • Traditional Chinese medicine composition for treating kidney deficiency and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Embodiment 1: the preparation of capsule

[0078] prescription:

[0079] Epimedium 1000g, Cnidium 1000g, Cistanche 1000g, Ligustrum 800g, Rehmannia glutinosa 750g, Schisandra 600g, Cynomorium 500g, Morinda officinalis 500g, Cuscuta 400g, Raspberry 400g, Psoralen 400g, Ginseng 300g, Mulberry 300g octopus, 25g velvet antler, 25g hippocampus, 200g starch, 800g microcrystalline cellulose, 50g silicon dioxide, 50g talcum powder.

[0080] Preparation method:

[0081] Antler and hippocampus were soaked and extracted with 85% ethanol with 6 times the amount of medicinal materials for 24 hours, filtered, and the filtrate was concentrated to a relative density of 1.10~1.15 under the conditions of temperature 50°C, steam pressure 0.12MPa, and vacuum degree 0.02MPa (30°C) The extract is dried in a vacuum belt dryer at a temperature of 55°C, a vacuum pressure of -1.0MPa, a feed rate of 15L / h, and a material belt conveying speed of 25cm / min into a dry paste, crushed, and passed thr...

Embodiment 2

[0086] Embodiment 2: the preparation of tablet

[0087] prescription:

[0088] Epimedium 800g, Cnidium 800g, Cistanche 800g, Ligustrum lucidum 700g, Rehmannia glutinosa 650g, Schisandra 500g, Cynomorium 400g, Morinda officinalis 400g, Cuscuta 300g, Raspberry 300g, Psoralen 300g, Ginseng 200g, Mulberry 250g octopus, 20g velvet antler, 20g hippocampus, 400g starch, 500g microcrystalline cellulose, 50g sodium carboxymethyl starch, 25g magnesium stearate, 25g talcum powder.

[0089] Preparation method:

[0090]Antler and hippocampus were soaked and extracted with 65% ethanol with 8 times the amount of medicinal materials for 24 hours, filtered, and the filtrate was concentrated to a relative density of 1.10~1.15 under the conditions of temperature 80°C, steam pressure 0.04MPa, and vacuum degree 0.02MPa (30°C) The extract is dried in a vacuum belt dryer at a temperature of 40°C, a vacuum pressure of -1.0MPa, a feed rate of 15L / h, and a belt conveying speed of 25cm / min into a dry ...

Embodiment 3

[0095] Embodiment 3: the preparation of soft capsule

[0096] prescription:

[0097] Epimedium 1200g, Cnidium 1200g, Cistanche 1200g, Ligustrum 900g, Rehmannia glutinosa 850g, Schisandra 700g, Cynomorium 600g, Morinda officinalis 600g, Cuscuta 500g, Raspberry 500g, Psoralen 500g, Ginseng 350g, Mulberry Octopus 350g, deer antler 30g, hippocampus 30g, gelatin 700g, glycerin 300g, ethylparaben 2g, titanium dioxide 2g

[0098] Preparation method:

[0099] Antler and hippocampus were soaked and extracted with 75% ethanol with 7 times the amount of medicinal materials for 24 hours, filtered, and the filtrate was concentrated to a relative density of 1.10~1.15 under the conditions of temperature 60°C, steam pressure 0.06MPa, and vacuum degree 0.04MPa (30°C) The extract is dried in a vacuum belt dryer at a temperature of 50°C, a vacuum pressure of -1.0MPa, a feed rate of 15L / h, and a material belt conveying speed of 25cm / min into a dry paste, crushed, and passed through a 60-mesh si...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating kidney deficiency and a preparation method thereof. The traditional Chinese medicine composition comprises epimedium, common cnidium fruit, desertliving cistanche, glossy privet fruit, prepared rehmannia root, Chinese magnoliavine fruit, songaria cynomorium herb, morinda root, seeds of Chinese dodder, palmleaf raspberry fruit, malaytea scurfpea fruit, ginseng, mantis egg-case, hairy deerhorn, hippocampus and the like. The preparation method includes: crashing residues into powder with the particle diameter smaller than 10 micrometers after ethanol extraction of the hairy deerhorn and the hippocampus, preparing other medicinal materials into extracts or dry extract powders via water extraction or ethanol extraction, and adding pharmaceutically acceptable additives to prepare oral solutions, powders, granules, tablets, capsules, soft capsules, pills, dripping pills and other oral medicaments. Since the residues of the two precious medicinal materials of the hairy deerhorn and the hippocampus are crushed to be used as medicine after ethanol extraction, contents of active ingredients in the medicaments are increased remarkably. The extracts of other medicinal materials are dried by the aid of a vacuum belt drying method, so that production efficiency is improved obviously, and energy saving and consumption reducing are achieved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating kidney deficiency and a preparation method thereof. Background technique [0002] According to traditional Chinese medicine, the kidney is a very important organ, which is called the innate foundation. The main physiological functions of the kidney are: the main storage of essence, the main water, and the main intake of qi. Because the kidney stores the innate essence, governs reproduction, and is the origin of human life, the kidney is called the "innate essence". Kidney essence transforms kidney qi, and kidney qi is divided into yin and yang. Kidney yin and kidney yang can help, promote, and coordinate the yin and yang of the whole body, so the kidney is also called "the foundation of yin and yang in the five internal organs". Kidney deficiency refers to that kidney vital essence negative and positive are not...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61P1/14A61K35/32A61K35/56A61K35/64A61K35/60
Inventor 谢称石秦超张兰袁帅
Owner GUANGDONG HUANAN PHARMACEUTICAL GROUP CO LTD