High-yield levulinic acid ester preparation method under catalysis of solid acid

Abstract

The invention discloses a high-yield levulinic acid ester preparation method under catalysis of solid acid and belongs to the field of organic synthesize. The method comprises the following steps: uniformly mixing 1 part of sugar, 10-100 parts of alcohol, 0.01-0.2 part of acid B and 0.1-1 part of acid L, and performing reaction under the temperature of 130-190 DEG C for 1-20 h to obtain a levulinic acid methyl ester solution, wherein the acid L is stanniferous molecular sieve, and the acid B is SBA-15-SO3H, Carbon-SO3H or Amberlyst-15. According to the method, the carbohydrate is low in cost and easy to obtain; with the acid B and acid L which can be used repeatedly, the catalysis effect basically remains the same; the levulinic acid ester compound prepared in one step can be widely applied to industries of food additives, essence spices, chemical reaction intermediates, gasoline, diesel-dopes and the like.

Description

technical field

[0001] The invention belongs to the field of organic synthesis, and relates to a method for preparing levulinic acid ester with solid acid catalysis and high yield. Background technique

[0002] In the traditional method of preparing levulinic acid, cheap water is used as solvent, but a large amount of humin is produced, resulting in low yield. Recently, researchers have begun to study the reaction behavior of sugars when alcohols (especially methanol) are used as solvents. When water is used as a solvent, the intermediate 5-hydroxymethylfuran is prone to side reactions to generate humin, which leads to a decrease in the yield of LA; while when methanol is used as a solvent, 5-hydroxymethylfuran can first react with methanol to form humin, which is not conducive to The produced intermediate thus increases the yield of levulinate.

[0003] Riisager et al. (Catalysis Communications, 2011, 17:71-75.) studied under relatively mild conditions (140°C, ethanol sol...

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