A kind of yeast glutathione nutritional preparation

A technology for nutritional preparations and yeast nutrition, applied in medical preparations containing active ingredients, tripeptide ingredients, food preparation, etc., can solve problems such as increased liver metabolism and detoxification burden, decreased antioxidant capacity, tissue damage, etc. It is beneficial to human body utilization, eliminates toxins from the body, and has low environmental requirements.

Active Publication Date: 2015-11-04
BEIJING KAWIN TECH SHARE HLDG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In severe diseases such as trauma and sepsis, a large amount of Gln in skeletal muscle is absorbed, and consumption is greater than synthesis, resulting in various symptoms such as relative deficiency of Gln, intestinal mucosal atrophy, translocation of bacteria and endotoxin, and the antioxidant capacity in the body Ability to decline, generate a large number of oxygen free radicals, causing tissue damage, greatly increasing the burden of liver metabolism and detoxification

Method used

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  • A kind of yeast glutathione nutritional preparation
  • A kind of yeast glutathione nutritional preparation
  • A kind of yeast glutathione nutritional preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1 is rich in the preparation of the Saccharomyces cerevisiae fermented liquid that is rich in GSH

[0023] Saccharomyces cerevisiae1251 was purchased from: China Industrial Microbiology Culture Collection Management Center

[0024] Insert strain Saccharomyces cerevisiae into plate culture medium BMGY, culture temperature 26-30°C, after 6-8 days, then move to slant medium BMGY, 26-30°C, 6-8 days to obtain slant spores.

[0025]Use a sterile inoculation loop to dig out 0.5-1cm 2 The slant spores of the first-level seed medium BMGY were cultivated at 26-30°C for 20-30h, and then the first-level seeds were inoculated into the next-level seed medium BMGY, and cultivated at 26-30°C for 20-30h. The inoculation amount of each level of seeds is 10%.

[0026] Insert the last level of seeds into the fermentation medium with an inoculum size of 10%. Medium contains: glucose 25g / l, yeast powder 15g / l, wort 60g / l, ammonium phosphate 10g / l, magnesium sulfate 5g / l, dipota...

Embodiment 2

[0028] Embodiment 2 is rich in the preparation of the Saccharomyces cerevisiae fermented liquid that is rich in GSH

[0029] Saccharomyces cerevisiae1210 was purchased from: China Industrial Microorganism Culture Collection Management Center

[0030] Medium contains: glucose 25g / l, yeast powder 15g / l, wort 60g / l, ammonium phosphate 10g / l, magnesium sulfate 5g / l, dipotassium hydrogen phosphate 1g / l, potassium dihydrogen phosphate 1g / l, chlorine Calcium 10mg / l, sodium chloride 1mg / l. The culture temperature is 26-28°C, the tank pressure is 0-0.05MPa, the air volume is 1:1-1:2 by volume, the pH is controlled at 6.0 during the fermentation process, glycerin is added after the fermentation starts, and the glycerin concentration is 100g / L. The total glycerol content is 2.0g / 100ml, add inorganic selenium ions, the addition amount is 20mg / L, add 8mmol / l L-cysteine, L-glutamic acid, glycine and 4mmol / l adenosine triphosphate after 1 day of fermentation, Ferment for 96h and collect th...

Embodiment 3

[0031] Embodiment 3 is rich in the preparation of the Saccharomyces cerevisiae fermented liquid that is rich in GSH

[0032] Saccharomyces cerevisiae1337 was purchased from: China Industrial Microorganism Culture Collection Management Center. Bacteria were irradiated with 10W UV lamp at 25cm for 3min, turned off the UV lamp, and placed in the dark for 5min. The obtained mutagen has higher GSH production capacity. Medium contains: glucose 25g / l, yeast powder 15g / l, wort 60g / l, ammonium phosphate 10g / l, magnesium sulfate 5g / l, dipotassium hydrogen phosphate 1g / l, potassium dihydrogen phosphate 1g / l, chlorine Calcium 10mg / l, sodium chloride 1mg / l. The culture temperature is 26-28°C, the tank pressure is 0-0.05MPa, the air volume is 1:1-1:2 by volume, the pH is controlled at 6.0 during the fermentation process, glycerin is added after the fermentation starts, and the glycerin concentration is 100g / L. The total glycerol content is 2.0g / 100ml, add inorganic selenium ions, the add...

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Abstract

The invention relates to a nutrition preparation which is rich in nutrition and has an effect of protecting the liver. The nutrition preparation is mainly prepared from GSH-enriched brewer's yeast dried powder, L-Gln and an acceptable excipient in the nutrition preparation. According to the nutrition preparation in the invention, the nutritional ingredients in the yeast are fully utilized, and the nutrition preparation has a better effect of protecting liver injury.

Description

technical field [0001] The present invention relates to a nutrition preparation with rich nutrition and the function of protecting the liver. The nutrition preparation is mainly made of GSH, L-Gln and Saccharomyces cerevisiae dry powder, and the GSH is Saccharomyces cerevisiae rich in GSH , for the field of biological health food. Background technique [0002] Glutathione, namely γ-L-glutamyl-L-cysteinyl-glycine (γ-L-glutamyl-cysteinyl–glycine, GSH for short). In 1888, Pailhode first discovered glutathione in yeast extract, which is composed of glutamic acid, cysteine ​​and glycine. [0003] Glutathione is the most abundant small molecule thiol compound in cells. Reduced glutathione is the main component of non-protein sulfhydryl groups in cells. It has a variety of physiological functions of traditional Chinese medicine in living tissues: GSH participates in redox reactions in cells, is a coenzyme of certain enzymes, and activates some sulfhydryl enzymes; provides reduced...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/06A23L1/305A61P1/16A61P37/04A61P3/02A23L31/10A23L33/18
CPCA23L33/00A23V2002/00A61K9/14A61K9/1635A61K9/4866A61K31/198A61K36/064A61K38/06A23V2250/762A23V2250/55A23V2200/30A61K2300/00A23V2200/32A23V2250/31A23V2250/062
Inventor 付大雁
Owner BEIJING KAWIN TECH SHARE HLDG
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