Traditional Chinese medicine external suppository for treating women morbid leucorrhea and preparation method thereof

A technology of suppository and traditional Chinese medicine, which is applied in the field of external Chinese medicine suppository for women's leukorrhagia and its preparation, which can solve problems affecting work and quality of life, repeated attacks of patients, and affecting quality of life, etc., and achieves convenient administration and endometrial repair. Effect of improving and relieving pain

Inactive Publication Date: 2015-02-18
QINGDAO HENGBO INSTR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Most of the patients taken off have recurrent attacks, lingering and difficult to heal, affecting the quality of life
Although most patients seek treatment in var

Method used

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  • Traditional Chinese medicine external suppository for treating women morbid leucorrhea and preparation method thereof
  • Traditional Chinese medicine external suppository for treating women morbid leucorrhea and preparation method thereof
  • Traditional Chinese medicine external suppository for treating women morbid leucorrhea and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0047] Preparation method 1 of the suppository of the present invention: Take 1500g of Angelica dahurica, 1500g of myrrh, 1500g of Atractylodes atractylodes and 1500g of notopterygium, vaporize them into crystals by distillation, crush them, pass through a 100-120 mesh sieve, and make them into fine powder for later use. Add 1500g of Smilax tuckahoe, 1500g of plantago seed, 1500g of salvia miltiorrhiza, 1500g of baicalensis, 1500g of forsythia, 1500g of Hedyotis diffusa, 1500g of cnidium, 1500g of Cortex Phellodendri, 1500g of Sophora flavescens, 1500g of Radix 1500g, intermittent 1500g of Radix Paeoniae Rubra, 1500g was cut into coarse grains, then soaked in ethanol for 2 hours. Then heat and extract twice, each time for 1-2 hours, combine the extracts, remove the supernatant after standing still, then filter through 100-120 mesh, and then ultrafilter through an ultrafiltration column with a cut-off molecular weight of 5000-10000. Concentrate the extract with a relative densi...

Embodiment 3

[0069] Embodiment 3: Vaginal mucosa irritation test result

[0070] 1. Test method:

[0071] After 3 days of experimental animal quarantine, select 18 above-mentioned healthy rabbits for use, and be randomly divided into three groups, each group of 6, respectively: blank control, excipient control, suppository group of the present invention (5 times concentration by application solution). Sterilized tampons of appropriate size soaked in sterilized physiological saline and the test substance were placed in the vagina of the animals in the vehicle control group and the test substance group, and were in contact with the vaginal mucosa for 6 hours, and the animals were sacrificed 24 hours later. The local vaginal tissue was taken out and the lesion was observed.

[0072] 2. Test results: vaginal mucosa irritation test results

[0073]

[0074]

Embodiment 4

[0075] Embodiment 4: skin allergy test result

[0076] Use the suppository of the present invention to carry out induction and excitation contact tests, observe the test mice after 24 hours and 48 hours, and there is no phenomenon such as erythema and edema in the skin, and there is no difference with the negative control group. The results show that the suppository has close to zero skin reaction intensity, that is, no skin allergy.

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Abstract

The invention provides a traditional Chinese medicine external suppository for treating women morbid leucorrhea. The suppository comprises the following crude drugs in parts by weight: 10-20 parts of rhizoma smilacis glabrae, 10-20 parts of semen plantaginis, 10-20 parts of salviae miltiorrhizae, 10-20 parts of notopterygium root, 10-20 parts of scutellaria baicalensis, 10-20 parts of rhizoma atractylodis, 10-20 parts of fructus forsythia, 10-20 parts of fructus cnidii, 10-20 parts of cortex phellodendri, 10-20 parts of radix angelicae, 10-20 parts of radix sophorae flavescentis, 10-20 parts of oldenlandia diffusa, 10-20 parts of myrrh, 10-20 parts of radix stemonae, 10-20 parts of teasel root and 10-20 parts of red peony root. The traditional Chinese medicine external suppository has the efficacies of clearing heat and promoting dieresis, and tonifying qi and resolving stagnation, and is used for treating the symptoms such as hypogastralgia, leukorrhagia, yellow and thick leucorrhea, lumbosacral pain and fatigue caused by damp and hot retardation. The external suppository is carefully developed by adopting a modern processing method on the basis of traditional medicine; and effective components of the raw material medicines are scientific in compatibility. Compared with an oral preparation, relatively few drugs are absorbed by the whole body; and the drugs are mainly focused on local parts to play a role of treatment, so that the side effects are relatively few.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, in particular to a suppository for external use of traditional Chinese medicine for treating vaginal discharge in women and a preparation method thereof. Background technique [0002] Leukorrhea refers to the symptoms of women with significantly increased vaginal secretions, abnormal color, quality, and odor. Abnormal vaginal discharge can often be seen in cold-damp or damp-heat injections, or infiltration of heat and toxins, or insufficiency of spleen and kidney yang qi. Leucorrhea is generally seen in local infection of vulva with evil poison, or lesions of the uterus, etc., and is most common in leukorrhea. However, those who are weak or have phlegm-dampness can also see a large amount of vaginal discharge. [0003] In normal women, since puberty, the kidney qi is abundant, the temper is healthy, the conception vessel is adjusted, and the pulse is strong. The...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61K9/02A61P15/00
CPCA61K36/90A61K9/02A61K36/185A61K36/232A61K36/234A61K36/237A61K36/284A61K36/328A61K36/489A61K36/537A61K36/539A61K36/634A61K36/65A61K36/68A61K36/71A61K36/748A61K36/756A61K36/896A61K36/904A61K47/44A61K2236/33A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 不公告发明人
Owner QINGDAO HENGBO INSTR
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