Regenerated silk fibroin gel mask and preparation method thereof

Abstract

The invention discloses a regenerated silk fibroin gel mask and a preparation method thereof. The specific preparation method comprises the following steps: (1) directly dissolving degummed silk into a formic acid solution containing salt, and drying to obtain a silk fibroin mask containing salt; and (2) directly soaking the dried mask into an alcoholic solution or water, so as to prepare the regenerated silk fibroin gel mask. Compared with the prior art, the gel mask has the advantages of traditional silk fibroin mask and hydrogel, is transparent, excellent in mechanical property and high in moisture content, and simultaneously has a biomimetic nanometer fiber structure, good degradability and good biocompatibility; and in addition, the gel mask is simple in preparation method, short in flow and easy to achieve mass production. The gel mask has excellent physical and chemical properties and biological characteristics, so that the regenerated silk fibroin gel mask has a wide application prospect in the fields of cosmetics and regenerative medicines, such as masks, skin dressing, dura mater cerebralis, corneas, anti-adhesive films, nerve sheath pipes and the like.

Description

technical field

[0001] The invention relates to a silk fibroin gel material and a preparation method thereof, in particular to a transparent silk fibroin gel film and a preparation method thereof. The method is simple and efficient and can be widely used in the fields of biology and medicine. Background technique

[0002] my country is the main producer of silk, and its silk output accounts for more than 70% of the world's output. In recent years, the research and application of silk has extended from the traditional textile field to high-tech fields, such as optoelectronics and biomedical materials, especially as biomedical materials have made important progress. Silk fibroin is obtained by degumming silk. It is a natural structural protein without physiological activity. It is mainly composed of three simple amino acids: glycine, alanine and serine, which account for about 85% of the total protein. The degummed silk has good biocompatibility and mechanical properties, and...

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