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traditional Chinese medicine composition for treating cardiovascnlar and cerebrovascular diseases

A technology of cardiovascular and cerebrovascular diseases and compositions, applied in the field of traditional Chinese medicine compositions, can solve problems such as patients’ resistance to taking medicines, sores or numbness of limbs, stomach discomfort, etc., to improve cardiovascular and cerebrovascular circulation and reduce blood viscosity , dizziness improvement effect

Inactive Publication Date: 2015-05-06
QINGDAO CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

3. Smoking
Observation shows that western medicine has obvious curative effect in treating special cardiovascular and cerebrovascular diseases, but it is generally reported that there will be a series of adverse reactions such as stomach discomfort, nausea, sores at the corners of the mouth, or numbness of limbs to varying degrees.
The above adverse reactions can make patients resist taking medicines
[0005] In view of the contraindications and side effects of the above-mentioned western medicine for the treatment of cardiovascular and cerebrovascular diseases, the inventor obtained a traditional Chinese medicine composition with obvious therapeutic effect and small side effects through a lot of practice.

Method used

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  • traditional Chinese medicine composition for treating cardiovascnlar and cerebrovascular diseases
  • traditional Chinese medicine composition for treating cardiovascnlar and cerebrovascular diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Preparation of pharmaceutical granules of the present invention

[0042] Chinese medicine composition raw material preparation:

[0043] Panax notoginseng extract: Use notoginseng in the winter of the third year after planting, remove the fibrous roots, dry it until the surface is free of moisture, then crush it into a drug powder with a particle size of 50-100um, and extract it with 70% (v / v) ethanol ultrasonically. times, the extraction time is 1.5h, 1.0h and 0.5h in sequence. After extraction, heat at 50~65°C to remove ethanol, and add the remaining extract to distilled water to dilute, so that the ethanol content in the dilution does not exceed 0.5%, and then use a hollow Fiber membrane filter is carried out ultrafiltration, wherein ultrafiltrate, concentration, macroporous adsorption resin column adsorption, water washing, 50% (v / v) ethanol elution, decompression concentration, vacuum drying obtains notoginseng saponin extract; After analysis Notoginsenoside R g1...

Embodiment 2

[0048] Embodiment 2 The preparation of medicine pill of the present invention

[0049] Preparation of traditional Chinese medicine composition:

[0050] Panax notoginseng extract: Use notoginseng in the summer of the third year after planting, remove the fibrous roots, dry it in the sun until the surface moisture content is 1%, and then crush it into the original drug powder with a particle size of 10~50um, and use 50% (v / v) ethanol Ultrasonic extraction 3 times, each extraction time is 1.5h, 0.8h and 0.5h, wherein the amount of ethanol is 28 times the weight of the original drug (10 times the weight of the original drug is added to ethanol for the first purification, and the original drug is added for the second purification) 8 times of the weight of the medicine, ethanol of 10 times of the weight of the original medicine is added for the third purification), wherein the extraction temperature is 60°C; after extraction, the rotary evaporation removes the ethanol, so that ther...

Embodiment 3

[0055] Embodiment 3 Preparation of pharmaceutical tablet of the present invention

[0056] Raw material preparation of traditional Chinese medicine composition

[0057] Panax notoginseng extract: Use notoginseng after autumn in the third year after planting, wash and dry to make the surface moisture content of notoginseng 0.5%, and then crush it into the original drug powder with a particle size of 10~20um, use 50% (v / v) Ultrasonic extraction of ethanol for 3 times, each extraction time is 1.5h, 1.2h and 0.4h, wherein the amount of ethanol is 23 times of the weight of the original drug (10 times of the weight of the original drug is added to ethanol for the first purification, the second time Purify by adding 5 times of ethanol of the original drug weight, the third ethanol dosage is 8 times of the original drug), wherein the extraction temperature is 70 °C; after extraction, the rotary evaporation removes ethanol, so that the ethanol content in the extract is 0.2%, and then ...

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Abstract

The invention provides a traditional Chinese medicine composition for treating cardiovascnlar and cerebrovascular diseases, belonging to the field of traditional Chinese medicine compositions. The invention provides a traditional Chinese medicine composition, which is good in curative effect and less in side effects, and is used for treating cardiovascnlar and cerebrovascular diseases. The traditional Chinese medicine composition comprises the following raw materials: Radix Notoginseng extract, Ginkgo Biloba extract, Radix Angelicae Sinensis extract, ephedra, radix scrophulariae and carriers according to the weight part ratio of (0.03-0.1):(0.05-0.21):(0.03-0.14):(1-3):(2-7):(10-110). The active pharmaceutical ingredients are combined with medically acceptable carriers to prepare tablets, pills, powder, tincture, suspension, emulsion, solution, syrup, aerosol agents or capsules. The traditional Chinese medicine composition is used for treating cardiovascnlar and cerebrovascular diseases such as cerebrovascular sequelae, coronary heart disease, or peripheral vascular disease. The cure rate of the traditional Chinese medicine composition on treatment of the cardiovascnlar and cerebrovascular diseases is up to 90%, with recurrence, and the traditional Chinese medicine composition is safe to take and free from side effects.

Description

technical field [0001] The invention provides a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases, belonging to the field of traditional Chinese medicine compositions. Background technique [0002] Cardiovascular and cerebrovascular diseases are collectively referred to as cardiovascular and cerebrovascular diseases, which have the characteristics of "high morbidity, high disability rate, high mortality rate, high recurrence rate, and many complications" and seriously threaten human life and health. The pathogenesis of cardiovascular and cerebrovascular diseases has: 1. Hypertension. Long-term hypertension can thicken or harden the walls of cerebral arteries and narrow the lumen. When blood pressure rises sharply, cerebral blood vessels are prone to rupture and cerebral hemorrhage occurs; or the hardened cerebral arterioles form a microaneurysm, and when the blood fluctuates, the arterioles rupture and cause cerebral hemorrhag...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/808A61P9/00A61P9/10A61P9/14
Inventor 史春雷
Owner QINGDAO CENT HOSPITAL
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