This invention has disclosed one kind and missed strata and bored and stopped up leaking at the same time seriously, well drilling liquid, it makes up, weight share: (A) Base thick liquid: Alta-mud 4-6, soda ash 0.2-0.3, water is 100, additive 1) carry and glue pharmaceutical SD-LHV 0.5-3, 2) lower and strain and lose pharmaceutical SK-III 0.5-2.5, 3) the flowing type regulates pharmaceutical SD-R 0.5-2.5, 4) the density regulates pharmaceutical SD-D 0.5-5, 5) pack and strengthen pharmaceutical MF-1, 6) join pharmaceutical MD-III 2-15, 7) the brige stops up pharmaceutical MD-III 8-20. This invention has function more, have a good adaptability, can already be used as stopping up and leaking the liquid, can be used as the well drilling liquid, can either use and miss layer apply Gao to permeate layer low-voltagly or, crack cave with stalactites and stalagmites type stratum, and leak and stop up with the characteristics, such as layer, etc.. It is miss to is it stop up leak and well drilling of the craft to get into at the same time stratum seriously to apply mainly.