Chlorhexidine gluconate bath disinfection liquid and preparation method thereof

Abstract

The present invention relates to a disinfection liquid. The chlorhexidine gluconate bath disinfection liquid comprises, by weight, 1.5-2.5% of CHG, 0.3-1.5% of a compound preservative, 0.5-2.0% of a thickening agent, 2.0-10.0% of a surfactant, 0.5-5.0% of a skin moisturizing agent, 0.5-5.0% of a moisturizing agent, 0.1-2.0% of a penetrant, a proper amount of a pH value regulating agent, and the balance of water. The preparation method comprises: adding a sufficient amount of water to a reaction kettle, heating to a temperature of 50 DEG C, adding the thickening agent under stirring, completely swelling after 30 min, sequentially adding the surfactant, the skin moisturizing agent, the moisturizing agent, the penetrant and the pigment, uniformly mixing, then adding the CHG, stirring for 10 min, cooling to a room temperature, adding the preservative and the essence, stirring for 5 min, adjusting the material liquid to achieve the weak alkaline state, standing, and defoaming. According to the present invention, the CHG can quickly penetrate into the skin stratum corneum and can be adsorbed on the stratum corneum so as to achieve the rapid, complete and durable sterilization purpose.

Description

technical field

[0001] The invention relates to a disinfectant, in particular to a rinse-free bath disinfectant. Background technique

[0002] The Ministry of Health issued the "Administrative Measures for Antimicrobial Drugs in Medical Institutions" in 2011, which stipulates that prophylactic drugs should be used 30 minutes to 2 hours before surgery, and the course of treatment should not exceed 24 hours. It is required that the proportion of prophylactic use of antibiotics for patients undergoing type I incision surgery should not exceed 30%, and the time should not exceed 24 hours, that is, 70% of type I incision operations cannot use antibiotics. If a medical institution "fails the antimicrobial drug application assessment" in the supervision and assessment, it will be downgraded or downgraded. Because the skin disinfection immediately before the operation cannot completely kill all bacteria, the only way to reduce the amount of bacteria on the skin is to take a bath be...