A kind of dendrimer polyamide ester quaternary ammonium salt and its synthesis process
A technology of polyamide-type ester and base quaternary ammonium salt, which is applied in the field of surfactants and can solve the problems of non-compliance with green chemistry, single structure, and weak functionality.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0037] Synthesis of the first generation PAMAM:
[0038] Weigh 20.0g (0.332mol) of ethylenediamine and (171.9g, 179.8mL) (2mol) of methyl acrylate, add them into a 250mL three-necked flask, heat the oil bath to 40°C, stir and react for 24h, and the reaction is basically completed. Excess methyl acrylate was recovered by distillation under reduced pressure to obtain 134 g of 0.5 generation PAMAM compound with a yield of 98%.
[0039] The obtained 134g intermediate was added to (398g, 442mL) (6.6mol) ethylenediamine, closed and reacted at room temperature for 24h, the reaction was basically completed, the excess ethylenediamine was removed by distillation, and 170g of the 1.0 generation PAMAM compound was obtained, with a yield of 99%. %.
Embodiment 2
[0041] Synthesis of the first generation tertiary amine-terminated polyamide PAMAM compound:
[0042] Weigh 20.0g (0.332mol) of ethylenediamine and (171.9g, 179.8mL) (2mol) of methyl acrylate, add them into a 250mL three-necked flask, heat the oil bath to 40°C, stir and react for 24h, and the reaction is basically completed. Excess methyl acrylate was recovered by distillation under reduced pressure to obtain 134 g of 0.5 generation PAMAM compound with a yield of 98%.
[0043] Add 134g of the obtained intermediate into (584g, 689mL) (6.6mol) N,N-dimethylethylenediamine, seal the reaction for 24h, the temperature is 45°C, the reaction is basically completed, and the excess N,N-di Methylethylenediamine was used to obtain 206 g of a 1.0-generation tertiary amine-terminated polyamide PAMAM compound, with a yield of 96%.
Embodiment 3
[0045] Synthesis of the first-generation tertiary amine-terminated polyamide PAMAM ester quaternary ammonium salt:
[0046] Slowly drop chloroacetyl chloride (50g, 0.44mol) into a suspension containing n-octanol (57g, 0.44mol) and sodium bicarbonate (74g, 0.88mol), and stir at room temperature for 4h. After the reaction, the organic phase was mixed with water After 500 mL of extraction, the organic phase was dried to obtain 90 g of chloroacetate intermediate with a yield of 98%.
[0047] Dissolve 90 g of the obtained chloroacetate intermediate and the first-generation tertiary amine-terminated polyamide PAMAM compound (104 g, 0.165 mol) in 1 L of absolute ethanol, and react at 80° C. for 36 h to obtain the chloroacetate intermediate After the reaction was complete, 190 g of the target product was obtained after rotary evaporation to remove absolute ethanol, with a yield of 96%.
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More