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Probiotics traditional Chinese medicine preparation for relieving yin-deficiency type constipation of elder people and preparing method and application of probiotics traditional Chinese medicine preparation

A technology of traditional Chinese medicine preparations and probiotics, applied in the biological field, can solve problems such as failure to quantitative analysis, and achieve the effects of relieving constipation due to yin deficiency in the elderly, improving resistance, and regulating body constitution

Inactive Publication Date: 2015-11-25
山东凤凰生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A systematic review by Chmielewska et al. in 2010 showed that some types of probiotics can improve constipation, but the above data could not be quantitatively analyzed due to data limitations

Method used

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  • Probiotics traditional Chinese medicine preparation for relieving yin-deficiency type constipation of elder people and preparing method and application of probiotics traditional Chinese medicine preparation

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Effect test

Embodiment 1

[0042] Example 1 Probiotic traditional Chinese medicine preparation composition 1 for relieving constipation of the elderly due to yin deficiency

[0043] The probiotic traditional Chinese medicine preparation composition for relieving constipation of the elderly due to yin deficiency, including traditional Chinese medicine and probiotics, specifically consists of the following components by weight:

[0044] Polygonatum 35 parts;

[0045] Polygonatum 10 parts;

[0046] Cassia seeds 20 parts;

[0047] wherein each gram of the composition is mixed with 10 9 CFU of Probiotics.

Embodiment 2

[0048] Example 2 Probiotic traditional Chinese medicine preparation composition 2 for alleviating yin-deficiency type constipation in the elderly

[0049] The formula of probiotic traditional Chinese medicine preparation for relieving constipation of elderly people with yin deficiency type includes a traditional Chinese medicine composition and probiotic bacteria, and is specifically composed of the following components by weight:

[0050] Polygonatum 60 parts;

[0051] Polygonatum 9 parts;

[0052] Cassia seeds 25 parts;

[0053] wherein each gram of the composition is mixed with 10 9 CFU of Probiotics.

Embodiment 3

[0054] The preparation of embodiment three probiotic Chinese medicine preparations

[0055] Experimental strains: Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus reuteri, Lactobacillus acidophilus and Bifidobacterium adolescentis.

[0056] Medium:

[0057] The formula of MRS solid medium is: glucose 2.0%, ammonium citrate 0.2%, sodium acetate 0.5%, dipotassium hydrogen phosphate 0.5%, manganese sulfate 0.02%, magnesium sulfate 0.05%, peptone 1.0%, beef extract 1.0%, yeast extract 0.5%, soil temperature-800.1%, 1.5% agar powder (imported), adjust pH6.0. Liquid media are solid media formulations without agar.

[0058] The formula of TPY solid medium is: casein peptone 1%, soybean peptone 0.5%, yeast powder 0.25%, dipotassium hydrogen phosphate 0.2%, MgCl 2 6H2O0.05%, calcium chloride 0.015%, ZnSO4 7H 2 O0.025%, ferric chloride 0.01%, L-cysteine ​​hydrochloride 0.005%, glucose 1.5%, Tween-801mL (1000mL plus 1mL), 1.5% agar powder (imported), adjust the pH to 6...

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Abstract

The invention belongs to the technical field of biology and particularly relates to probiotics traditional Chinese medicine preparation for relieving yin-deficiency type constipation of elder people and a preparing method and application of the probiotics traditional Chinese medicine preparation. The probiotics traditional Chinese medicine preparation comprises traditional Chinese medicine and probiotics, wherein the traditional Chinese medicine comprises, by weight, 30-70 parts of rhizoma polygonati, 1-15 parts of radix polygonati officinalis and 10-25 parts of semen cassia; the probiotics are one or more of lactobacillus plantarum, lactobacillus rhamnosus, lactobacillus reuteri, lactobacillus acidophilus and bifidobacterium adolescentis, and 108-109CFU of probiotics is mixed into each gram of the probiotics traditional Chinese medicine preparation. The preparing method of the probiotics traditional Chinese medicine preparation is simple to operate and easy in industrial production. The probiotics traditional Chinese medicine preparation is capable of relieving the yin-deficiency type constipation of elder people and capable of adjusting intestinal flora balance and increasing immunity at the same time, safe, long in storage life, and capable of being made into powder, tablets, capsules and the like.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a probiotic traditional Chinese medicinal preparation for relieving constipation of the elderly due to yin deficiency and a preparation method thereof. Background technique [0002] Constipation is the most common chronic gastrointestinal disease clinically, that is, constipation in stool, prolonged defecation interval, or difficult defecation even if it is not prolonged. The main manifestations are no more than 3 bowel movements per week; at least 25% of the time there will be less hard defecation, or difficult defecation, or poor defecation; and often have rectal distension, long-term forced defecation, incomplete defecation, abdominal distension and abdominal pain, etc. a series of syndromes. Symptoms of chronic constipation often last for more than 3 months. With the aging of society, changes in the pace of modern life and eating habits, constipation has increasingl...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P1/10A61K35/747A61K35/745
Inventor 单宝龙王静任宝涛李凤娟杨婷婷侯晓瑞孙海馨田兆才
Owner 山东凤凰生物科技股份有限公司
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